Imported Berries and the Source of Your Food | What you Need to Know to stay Healthy with Grace Gawler

The food we eat, lifestyle and it its impact on health remains controversial and confusing. Recent media exposure of some of the entrepreneurs of dietary approaches for cancer has brought even more confusion. What can you do realistically to improve health through nutrition? Can diet prevent cancer and more importantly can it impact growth of cancer once it has proliferated. I will be exploring these questions over the coming weeks.

The food we eat, lifestyle and it its impact on health remains controversial and confusing. Recent media exposure of some of the entrepreneurs of dietary approaches for cancer has brought even more confusion. What can you realistically do to improve health? Can diet prevent cancer and more importantly can it impact growth of cancer once it has proliferated. I will be exploring these questions over the coming weeks. Through our health promotion not for profit charity; and a series of informative blogs, my internet radio show “Navigating the Cancer Maze” and seminars; over the next few months we will be helping you navigate the complex cancer and nutrition maze.

Fresh Produce from the Sunday Farmer's Market Gold Coast Racecourse
Fresh Produce from the Sunday Farmer’s Market Gold Coast Racecourse

 The aim is to help you make better choices, become more connected with the food you eat and to buy and prepare food wisely. The latest food “wake-up call” for Australian consumers has been initiated by the Hepatitis A Berry debacle.

From the nutritional viewpoint, there is strong scientific evidence that eating blueberries, blackberries, strawberries and other berry fruits has beneficial effects on the brain and may help prevent age-related memory loss and other changes. (ACS’ Journal of Agricultural and Food Chemistry)

Phyto-chemicals in berries help increase brain function. Some top brain surgeons are now recommending increasing berries in your diet if you have a brain tumour.

http://www.sciencedaily.com/releases/2012/03/120307145825.htm

Nannas raspberries
Fresh homegrown raspberries

 High in antioxidants and  pigments beneficial to health; berries have always been a food that increases and value-adds to various functions within the body. During the past few years berries like so many other “what used to be called food that that was good for you”, have been elevated to celebrity status as “Superfoods”! The “Superfood” label has been a very successful marketing ploy that has convinced consumers to eat exotic foods grown in far away lands (Goji berries-Grown in China-imported to Australia, Chia seeds Grown in India/South America – imported to Australia and so on etc).

We need to heed the wake-up call re imported foods and education is pivotal to avoid health problems particular in those who are immune compromised through cancer or other illnesses.

Another recent example of an outbreak of symptomatic hepatitis A virus infections was in May 2013. The virus spread across 10 US states and was associated with imported frozen pomegranate arils imported from Turkey and manufactured in the USA by an organic group.  These were identified as the vehicle early in the investigation by combining epidemiology—with data from several sources—genetic analysis of patient samples, and product tracing. There were 165 cases known to have been affected. Hepatitis A is spread when human feces contaminate food or when an infected food handler prepares food without using proper hygiene. Human feces are expected as the cause of the outbreak, according to the Wall Street Journal.
http://www.natureworldnews.com/articles/2848/20130708/fecal-matter-pomegranate-seeds-linked-hepatitis-outbreak-southwestern.htm

  • No matter how “Super” a food is – our foods are still subject to spoilage, issues form light exposure, contamination from bacteria, viruses, environmental pesticides and in some countries of the world – even parasites; useful information when traveling, especially in parts of Asia.
  • Most people believe that home grown or organically farmed food is best and has superior taste – which is true; but it is not only the nutritional value of fresh food; food handling knowledge and storage is still important.
  • Just as important a question as what is in your food – is the question who has been handling your food before you?
  • Even though you may purchase beautiful produce from a Farmer’s market which I do – Cleaning, washing  and storing your fruit and vegetables appropriate is essential for good health. Proper food handling is a science in itself and by not adhering to basic principles; you can put your health at risk whether you are a cancer patient or not. Here is an example of poor food handling: Note the Farmers Market image top left top of page – THis is produce I bought last Sunday  – I washed all the produce – with the exception of potatoes. Note the dirt is still on the potatoes and they have direct contact with the lettuce leaves.  Given that the potatoes are grown organically contaminants from the dirt from animal/human faeces or other pathogens can easily migrate to to the lettuce which will be eaten raw.  Poor food handling method!
  • I have a great deal of healthy respect for the microscopic world- these humble little bugs; some which are good and some that are not good can quickly disable us and compromise health. Last year one of my cancer patients who was very pro raw produce had a significant life threatening incident when eggs from a local supplier had been contaminated with Clostridium. Within 10 minutes of ingesting his raw eggnog – he collapsed and within hours he was on life support in hospital. He recovered but the damage to his muscles and neurological system was extensive – he later died as a result of the bacterial onslaught. Another patient was making yoghurt from raw milk, warmed but not pasteurized, and almost lost their life due to bacterial contamination in the milk – a similar incident occurred when someone passed on to my client; a “special” yoghurt culture that had been made with raw milk – they became very ill and their cancer treatment was set back months due to the severity of the infection.
  • Prevent and know about food borne illness Download this excellent PDF Bacterial Foodborne Illness

External contaminants: About the safety of frozen berries – in particular Raspberries:

Cancer patients often use frozen berries as a tasty key ingredient to make their nourishing and ” bowel-friendly” smoothie drinks. So what the problem with eating frozen berries?

Frozen raspberries
Imported frozen raspberries

It all sounds as rosy as the berry’s colour itself; but for two facts – Hepatitis A contamination recently discovered in frozen raspberries imported from China; and in addition, high levels of pesticides and fungicides used on these foods.
Download the PDF;
“Know what’s in your frozen berries”: Brands under the microscope
http://www.ewg.org/foodnews/
http://www.ewg.org/foodnews/list.php

  1. Hepatitis A How did it get into frozen berries? Hepatitis A is transmitted by the “faecal-oral” route and is the only common food-borne disease preventable by vaccine. It is one of five hepatitis viruses that infect the liver. While hepatitis B and C can turn into chronic hepatitis, hepatitis A generally does not; although it can lead to liver failure and death.

People who have contaminated hands can transmit the virus. Hepatitis A is a contagious disease. It travels in faeces, and can spread from person to person, or can be contracted from food or water. In cases of contaminated food, it is usually the person preparing the food who contaminates it. The food handler will probably not know they have the virus, since the virus is most likely to be passed on in the first two weeks of illness, before a person begins to show symptoms.

So the infection that appears to be linked to Nanna’s Berries could have been spread by someone working at the processing plant, who was infected with hepatitis A and did not wash their hands properly before handling the berries. Alternatively, because the virus is excreted in stool, it could also be that a water supply that’s been contaminated with sewage containing hepatitis A virus has been the problem. Water from that source could have been involved in the processing. Human excrement deposited in a field could also be a source.
Freezing and the viability of the Hepatitis A Virus:

While the virus does not grow in the frozen food, but rather it remains suspended state. Even so, it remains infectious and is essentially preserved during transport.  When the food starts to thaw, the virus becomes active again. It’s not just viruses, like hepatitis A, but the bacteria we associate with food-borne illnesses, like salmonella, e- coli, listeria, these all can survive freezing temperatures.

Does cooking kill the hepatitis A virus?

While cooking can kill the virus, the food needs to be thoroughly heated to above 85 degrees Celsius. If you heat food for a minute or two at that temperature, you should kill hepatitis A; however if you heat it to a lower temperature than that, then it can still survive.

WHAT YOU CAN DO:
1. BERRIES- What can you do apart from discarding or returning any frozen berries? Berries are not the only culprits when it comes to health threats. Make a decision for you and your family’s health – eat local fresh foods in season – buy organic where possible especially the foods that that you consume the most and the ones known for pesticide contamination. Wash in vinegar solution, rinse and  dry off before storing. (http://www.ewg.org/foodnews/list.php)

2. Discover the location of your local Farmer’s Market – buy direct from the growers and following handling and storage rules.

3. Avoid consuming imported produce from unknown sources or countries known for using pesticides not permitted here: for example: FROM The Sydney Morning Herald (Feb 21 2015): consumer group Choice commented: The outbreak has highlighted concerns about country-of-origin labelling on food. Choice has tested 55 packs of frozen mixed fruits and mixed vegetables and found nearly half the labels on the packs had “vague” or “unhelpful” information.  Choice said some of the worst claims included “Packed in New Zealand”, “Packed in Chile from imported and local ingredients” and “Processed in Belgium”. (GG added –  But grown where?)

4. The case against raw food for cancer patients:

As per my example re raw eggs and raw milk – Consuming your vegetables raw can cause you to ingest bacteria or food borne illnesses that can actually be detrimental to your health. Understanding the risks associated with consuming raw vegetables will help you learn the importance of cooking your food thoroughly – yes “cooking foods” so you can avoid coming in contact with substances that may be toxic. Washing well may not always rid the produce of contaminants. For a healthy person – this might not be a problem – but for the immune compromised – it can be really serious.

You may be able to impact bacterial and pesticide/fungicide residues and viral contaminants by using good old fashioned vinegar. Professor Peter Collignon, infectious disease physician at the Australian National University’s Medical School, was asked about the value of vinegar for cleaning. I use it on all vegetables and fruits that I buy from the Market.
http://www.abc.net.au/health/talkinghealth/factbuster/stories/2012/02/02/3407024.htm

I shop each week at the Farmers Market – as soon as I unpack the produce at home, I soak all my produce in a vinegar solution – then rinse and dry and place if fridge. I keep soil contaminated produce away from other foods.

Please let me know if you have found this information helpful – Feedback helps me to know what you want to Know. If you have a question or topic you would like addressed on this blog or on my radio show from an expert in the field – please write to me via the contact page on this blog.

Until next time….Wishing you good health

Grace

Navigating the Vascular maze in Cancer Medicine | A Vascular Surgeon’s Experience | Clotting Risks and What You Can Do

According to Jean Connors, MD and medical director of Anticoagulation Management Services at Brigham and Women’s Hospital and Dana-Farber Cancer Institute; Cancer patients are at a higher risk than the general population of developing serious blood clots, including deep vein thrombosis (DVT) in the legs or pulmonary emboli in the lungs, which can be fatal.

Navigating the Vascular Maze in Cancer Medicine – Interview with vascular surgeon (now retired) Dr John Singe. To further this conversation I have added a number of resources and what I believe is very helpful information for anyone interested in health and wellbeing and disease prevention.

According to Jean Connors, MD and medical director of Anticoagulation Management Services at Brigham and Women’s Hospital and Dana-Farber Cancer Institute; Cancer patients are at a higher risk than the general population of developing serious blood clots, including deep vein thrombosis (DVT) in the legs or pulmonary emboli in the lungs, which can be fatal.

 DVTheart_dvt1“Of all the blood clots detected, 20 percent of them are detected in people who have cancer,” She says. Individuals over the age of 60 are at the highest risk of developing blood clots.

“There is a balance in the body between pro-clotting and anti-clotting activity,” says Connors. ”Cancer skews the balance in terms of pro-clotting, increases inflammation, and compresses blood vessels, all risk factors for developing clots.”
As well as a tendency to coagulate or clot; treatments for cancer or blood disorders can also affect the balance of pro and anti-clotting factors.
Immobility and increased bed rest during treatment also enhances a patient’s risk of developing a hyper coagulant state this is why many hospital patients are treated with heparin or some form of anti-coagulant medicine. When seated in a car or aeroplane for long periods of time, it is important to change position, take short walks when possible to keep your blood flowing and practice the simple exercise talked about in today’s interview on Navigating the Cancer Maze Select the title to be redirected to my internet radio show on Voice America’s Health and Wellness Channel. (Free to listen live streaming or to download on itunes.)
http://www.voiceamerica.com/episode/84200/special-encore-presentation-navigating-the-vascular-maze-in-cancer-medicine-clotting-risks-for
Patient risk of DVT and embolisms increases enormously with air travel to overseas cancer clinics and in my experience; the issue is often not addressed with diagnostic measures or treatment at these clinics. Unfortunately I have seen this scenario many times including when cancer patients are informed of the risks but are dedicated to a “natural cancer therapies” approach. These patients left their Clexane injections in their luggage to be considered for use at a later date. Cancer did not take their lives. Too many died as a result of DVT and resultant embolisms.

Of course if you have had DVT, embolisms or blood coagulation issues in the past it is essential to inform your treating doctor or oncologist. This is also a trap for patients being treated overseas where their complete medical history is not made available or where there are language and translation issues.

Formation of vascular blood clots is also a leading cause of death in cancer patients because cancer cells create blood_clotting (4)conditions that favour clotting. We know that patients diagnosed with pancreatic, lung cancer, multiple myeloma, or hematologic malignancies are more likely to develop blood clots than other cancer patients due to cancer-specific factors, including their treatment regimens. These patients should receive particular attention in terms of preventative anti-coagulation therapy to decrease risk of events that could be fatal.

Dr Connors states that 10 percent of people diagnosed with DVT who do not have a known cancer will be diagnosed with cancer as part of the clot evaluation or in the next year to two years!
PREVENTION AND AWARENESS:
Having seen so many patients with blood coagulation, DVT and embolisms; it serves as a warning sign that blood should be checked for coagulation problems as a part of wellness and disease prevention program. Did you know that egardless of cancer, if you are over 50; the greatest threat to your continued existence is the formation of abnormal blood clots in your arteries and veins. Even athletes and those who are physically fit can be at high risk.

Dietary management and adjustments can help reduce risk – as well as some plant-based phyto-chemicals that have been proven to decrease blood viscosity. However – self diagnosing blood coagulation problems and taking supplements for “blood-thinning” or even taking excessive amounts of foods known to help “thin the blood” is not recommended.

Could you possibly eat all this in one sitting if it wasn't juiced? Imagine this amount 6 or more times daily!
Could you possibly eat all this in one sitting if it wasn’t juiced? Imagine this amount 6 or more times daily!

Recently I had a patient who experienced massive bleeding during a biopsy procedure. Her surgeon had told her to avoid aspirin and fish oil for 5 days before her procedure – which she dutifully did. However she was juicing large amounts of fresh ginger daily as well as turmeric root and she was making a juice from cabbage, mustard greens and turnip greens broccoli, asparagus an apple.
She almost bled out on the operating table and has had a long recovery due to excessive blood loss. It is not hard to see why specialists say to cancer patients when asked if they can have certain foods and supplements – “TAKE NOTHING – AVOID SUPPLEMENTS AND DON’T CHANGE YOUR DIET TOO MUCH”.

When the famous Hippocrates said “Let your food be your medicine and your medicine be your food” he did not mean juicing a wheelbarrow load of fruit and veges every day!!!

It is useful to know that several herbal preparations ( natural and supplemental) interfere with the anti-clotting activity of blood thinners and can increase bleeding time or your risk of bleeding. Garlic, ginger, celery seed, ginseng, curcumin and aniseed all carry coumarin effects (meaning that they can prevent your blood from clotting…. the opposite coagulation focussed on in this article.). (NOTE: Avoid combining tumeric (active ingredient curcumin) with anticoagulant and/or antiplatelet drugs. If you take blood thinning medication

  • Due to “blood thinning” side effects of turmeric; cease to take it at least two weeks before any surgical procedure.
    Two other helpful suggestions about taking Tumeric ( cucumin)
  • Caution with Diabetes. Turmeric may lower blood sugar. Avoid turmeric if you take diabetes medications, since turmeric could cause your blood sugar to fall even further. This could result in hypoglycemia.
  • Caution with Gallbladder. The NIH recommends avoiding turmeric if you currently have problems with your gallbladder. If you have gallstones or a bile duct obstruction, turmeric may cause your condition to worsen.
    Foods rich in vitamin E are also natural blood thinners.

Botanical Science and nutritional science knowledge tend to be little adhered to by the current fad that more is better whether in juice, smoothie or supplement. People are flocking to buy machines that will pulverise 10 carrots and 4 blocks of tofu along with bunches of kale and spinach etc in the pursuit of “health and wellbeing”!

In fact these approaches can really have a negative impact of health and wellbeing which I am already seeing in my Practice.
Case managing patients who wish to use complementary medicines and nutritional approaches alongside conventional medicine – presents a challenging management situation to health practitioners.

In our practice I do my best alongside my colleague Dr Whelan to gain patient’s trust in advising on what to take as supplements and foods. With 87 years experience between us – we try to educate and advise simplicity as a targeted approach – rather than trying to “hit a mosquito with a shotgun” – the one size fits all approach. We know they will be tempted and influenced by fellow patients and incorrect information in books and approaches generated by faddist cancer entrepreneurs as well as Dr Google. Experience tells us that our educated patients do very well indeed.

  • As another example of the importance of botanical science knowledge and how a simple food might heal or hinder. While research suggests that tangeretin in mandarin oranges may help prevent cancer, people who already have cancer may not reap any benefits. In fact, a diet rich in mandarin oranges may provide counteractive results in these people as tangeretin appears to interfere with metabolism of some drugs, including the anti-cancer drug tamoxifen. Mandarins and grapefruit are just two of many foods that should be avoided due to interactions with life-saving pharmaceutical treatments.

ASK A HEALTH PROFESSIONAL WHO IS QUALIFIED AND EXPERIENCED IN CANCER AND HERB/NUTRITIONAL DRUG INTERACTIONS TO DESIGN A PERSONALIZED HEALTH RESTORATION PROGRAM FOR YOU.

Realise that your situation will change as response and treatments change. This is why regular communication and case management is imperative for every cancer patient.

For those cancer patients who live in Queensland – you might like to visit our Gold Coast based consulting rooms where Blood tests and other checks can be organised to increase your wellbeing and lower risks of blood disorders and assist with your cancer management program. More information? Email me via the contact page on this blog or visit www.gracegawlerinstitute.com or www.drwhelan.com

Recommendation – Ongoing Management:
If you are diagnosed with a blood clot, be sure to complete all age-appropriate cancer screenings, including mammograms, Pap smears, and colonoscopies, among others, to evaluate your cancer risk. If all tests are negative, implying no cancer is detected, then it has been recommended that the basic clinical evaluation is repeated every 6 months in the 2 years after the clot occurred. In this way, it is likely that most cancers, if they occur, will be promptly detected. If you know someone who has had DVT without a known cause – please direct them to the following video. We all know that early detection of cancer means better outcomes.

[youtube https://www.youtube.com/watch?v=uZmT0xgv2Z4&w=560&h=315]

RESOURCES:
http://www.stoptheclot.org/
http://www.stoptheclot.org/documents/fam_test.pdf
http://www.voiceamerica.com/episode/84200/special-encore-presentation-navigating-the-vascular-maze-in-cancer-medicine-clotting-risks-for
www.gracegawlerinstitute.com
http://www.cdc.gov/ncbddd/dvt/facts.html
http://www.cdc.gov/ncbddd/dvt/diagnosis.html

Until next time……
Grace

Why Innovative Oncology is an Effective Way to Tackle Cancer

Today on Navigating the Cancer Maze I speak with Prof Brendon Coventry about melanoma and in particular, vaccines against melanoma. But more than a melanoma treatment, Cancer Vaccines are showing up as not only as a part of innovative and integrated oncology approaches; but as likely treatments for other types of cancers that have failed conventional treatments such as radiation and chemotherapy protocols.

Today on Navigating the Cancer Maze I speak with Prof Brendon Coventry about melanoma and in particular, vaccines against melanoma. But more than a only a melanoma treatment, Cancer Vaccines are showing up as not only as a part of innovative and integrated oncology approaches; but as likely treatments for other types of cancers that have failed conventional treatments such as radiation and chemotherapy protocols. For example Jeffrey Deslandes, who after 4 recurrences of NH lymphoma – found his success with cancer vaccines. He is 9 years clear of the disease.

Prof Brendon Coventry with Grace Gawler
Prof Brendon Coventry with Grace Gawler

 The combination of Surgical Oncologist  in combination with a PhD in Immunology – is rare; but this is what Prof Coventry brings to the cancer “treatment table”. He has many years experience in cancer research, vaccine therapies and the role of the immune system in cancer control.

To Listen to audio of show – 4 sessions – select  each link below

Listen to Navigating the Cancer Maze-with Prof Brendon Coventry

Sessions one to four  with

Remember the show is for you and sponsored by our charity – The Grace Gawler Institute. It is free to air and free to listen live streaming within an hour of live broadcast. It is archived indefinitely on my Voice America Page. Crucial to the shows intention – to educate patients and families about the availability of  scientifically valid cancer treatments and safe and effective complementary medicine; we ask that you forward the ecard (available on the website) or URL to those you know who are trying to navigate the increasingly complex cancer maze.

Every week, some 160,000 people die of advanced cancer around the world, despite our best attempts at cancer treatment globally. Some $32 billion is being spent on oncology drugs and the USA National Cancer Institute/ NIH spends about $5.2 billion on cancer research, per annum. Sadly, cancer has remained a tremendously costly public health problem of major proportions for over 5 decades, and our progress has been puzzling slow towards solving this using standard methods.

On today’s show, Navigating the Cancer Maze, my guest Professor Brendon Coventry, an Adelaide-based oncology surgeon suggests there may be another way to approach the problem and shows that the immune system my hold the answer. With a special interest in Melanoma Surgery, he is a clinical researcher whose interests include anti-tumour immune response in human malignancies, tumour Immunology and cancer vaccine treatments.

His group’s research paper, published in 2014, entitled “Vaccinia Melanoma Cell Lysate Vaccine (VMCL) Trial for treatment of advanced Stage IV Melanoma with and without Chemotherapy”, captured the attention of medical and scientific community. Trial conclusions reported high complete response rates (where all cancer disappears) of 17%, with useful clinical responses occurring in nearly 80% of patients overall (slowing the disease), and over 15% of patients experiencing survivals past 5-years, with essentially no toxicity. The longest survivor now remains alive for over 14 years. These response rates and survivals are unusual for advanced melanoma. The researchers reason that the repetitive and prolonged delivery of the vaccine therapy might hold part of the clue, because this was a strikingly different approach to that used in other trials.

At this weeks Meeting of Minds in Brisbane Prof Coventry with Grace Gawler and Martin Ashdown
At this weeks Meeting of Minds in Brisbane (LtoR) Martin Ashdown with Grace Gawler and Prof Coventry

Prof Coventry with colleague Martin Ashdown, have now developed a remarkable understanding of how the human immune system continuously oscillates in a dynamic fashion. The timing of ‘when’ the therapy dose is precisely delivered in synchrony with each individual patient’s own immune system waveform or cycle might hold the very key to improving cancer treatment, thus leading to better survival.

Martin Ashdown says: …..”The concept of immune monitoring and accurately synchronizing therapy (immune synchronization), brings a new level of science to oncology. The published mouse experiments and human clinical trials, together with our knowledge of physiology tells us this is the way forward, particularly with the new cancer immunotherapies. This approach potentially has the triple benefit of increasing efficacy, lowering toxicity and substantially reducing the cost of treatment”

Professor Brendon Coventry is well crendentialled

Professor Brendon Coventry BMBS, PhD, FRACS, FACS, FRSM is an Associate Professor of Surgery at the University of Adelaide and Senior Consultant Surgeon (General, Breast-Endocrine, Surgical Oncology & Trauma Surgery) at the Royal Adelaide Hospital since 1993.

He holds a PhD in cancer immunology.

Positions:
• Immediate Past Chairman, Surgical Oncology Section, Royal Australasian College of Surgeons;
• Research Director, Australian Melanoma Research Foundation & Board Member;
• Past Chairman, Melanoma and Skin Cancer Group, Clinical Oncological Society of Australia;
• Foundation Chairman, Multidisciplinary Melanoma Management Group, Royal Adelaide Hospital
• Senior Examiner, Australian Medical Council
• Board Member of Cancer Care Centre, Unley

Fellowships:
• Royal Australasian College of Surgeons,
• American College of Surgeons
• Royal Society of Medicine.

Research:
• Over 85 journal publications; including New England Journal of Medicine, British Journal of Cancer, Journal of Clinical Oncology, Lancet Oncology; widely published topics including surgical treatment for melanoma and breast cancer, sentinel node surgery, sarcoma surgery, adjuvant radiation therapy, melanoma vaccine therapies,laparoscopic spleen surgery techniques, neuroscience, microscopic methods, high-sensitivity tissue immunochemistry, public health,
medical education, internet learning.
• NIH Principal Investigator: Multicenter Selective Lymphadenectomy Trial (MSLT-I) surgical sentinel node; C-Vax melanoma vaccine studies (x2).
• Editor-in-Chief, 7-Volume international textbook series “Surgery: Complications, Risks and Consequences” published by Springer; general adult, paediatric and cardio-vascular surgery.
Current Research:
• Surgical Complications, Safety and Quality improvement
• Vaccine Therapies for Advanced Melanoma, novel findings from repetitive dosing where 5-year survival and Complete Response rates have been significantly improved
• Timing of Therapies is novel collaborative work with Martin Ashdown concerning serial blood biomarker monitoring for advanced cancer patients for more accurate timing to improve therapy dose delivery and clinical efficacy further, which is gaining recognition

 

More on Vaccine successes – listen to Jeffrey Deslandes interviewed on Juice radio – Gold Coast yesterday 16 January 2015. https://soundcloud.com/juice-107-3/cancer-survivor-jeffrey-deslandes

Sometimes we can’t make financial donations for a cause – but we can use the internet, emails social media and word of mouth to help bring about change. Patient demand through critical need will make a difference- but voices are required! Please spread the word about this interview and the show and make your contribution to change the paradigm of treating cancer for the benefit of humanity.

Until next time
Grace

Can Fibre Diffraction Diagnosis Detect Cancer Years Before its Onset | Yes says Professor Veronica James

Navigating the Early Detection Maze! Just imagine if cancer could be detected long before the process of a mammogram or PSA test or scan discovered advanced disease? According to Physicist, Professor Veronica James who has devoted her life to Scientific Research in the area of early diagnosis; the answer is a resounding YES!

Navigating the Early Detection Maze! Just imagine if cancer could be detected long before the process of a mammogram or PSA test or scan discovered advanced disease?

Fibre Diffraction Diagnosis
Professor Veronica James

According to Physicist, Professor Veronica James who has devoted her life to Scientific Research in the area of early diagnosis; the answer is a resounding YES! Just imagine if she is right and there is a strong probability she is; earlier cancer diagnosis than we currently have access to, is possible! Interview Voice America:

Prof James has worked on breast cancer since the 1980s & developed Fibre Diffraction Diagnosis”, a method to detect cancer using x-rays of nail clippings, hair or skin. An unusual concept; but this almost 80 year old Australian scientist has the science and credibility to back up her research results.

One of the fears and anxieties amongst cancer patients I see, is their concern that they may have somehow passed on their cancer genes to the children or grandchildren. Wouldn’t it be wonderful for them to know there was a test that could lead to a clean bill of health or an early diagnosis?

Prof Veronica James is not a name that one recognizes unless you are in the academic research field; and so the question that begs to be asked is – Why Not? What happened to her research and findings and why hasn’t she had the funding to continue her work? These questions that require an answer.

I visited Veronica at her home this week to record an interview for my Voice America Internet Radio Show that aired today on Navigating the Cancer Maze. I was horrified to hear about her battles to get this invaluable contribution to cancer research recognised. Despite her credentials, she has had to fight tremendous battles to assert her research findings in Science. A snippet of the issues she has had to endure are to be found in the Herald-Sun article January 06, 2010!  Titled Professor Veronica James’s quest to shield others by Olga Galacho.  Well worth a read! Here is someone who I consider is a Grand Dame of Science in Australia, a National Treasure. Please contact me via the contact page on the menu if you would like to support Prof James research.

Her research and results from studying early diagnosis of breast cancer using Fibre Diffraction Diagnosis, is astounding.

This story of discovery is amazing and somewhat serendipitous. In 1996, Veronica reported to the medical personnel at Christie’s Hospital Manchester, the 4 changes she had observed in the collagenous ductal tissue of the breast that precede breast cancer noting that, in the final stage, the breast tissue had reversed to foetal tissue.

Rings identified by Prof Veronica James as disease states
Rings identified by Prof Veronica James as disease states

Veronica was asked whether she had observed similar foetal tissue in the skin as had been reported in breast cancer. A subsequent study at the local Daresbury synchrotron of 14 skin samples did show a possible foetal-like change similar to the penultimate change in the breast. Christie’ Hospital Oncologists agreed to provide 200 samples to confirm these results but when she arrived in England to collect them, the samples had disappeared from their freezer. As Veronica had already studied changes in hair in insulin dependent diabetes and was due in Japan the following day, she asked if a clinic was in progress and being told that it was asked if a hair sample could be taken from each of the participants. With hoots of laughter they agreed asking her what she thought she would find. Veronica told them nothing but that she would not be in disgrace in Japan for arriving without any samples. They were still laughing when she collected these samples the next day. When Veronica started to look at the samples the following day in Japan, she found strange rings superimposed on the normal hair patterns and after blaming and reassembling the machine she finally found out that only 8 of the 19 samples showed this ring.

Veronica sent back to England the numbers of these samples thinking that they might have something in common – same family, same shampoo, same hairdressers etc. Their return email stated simply that Veronica had picked out all the breast cancer patients. This was confirmed by taking these and further blinded sets to other synchrotrons. The changes relating to other cancers and Alzheimer’s Disease, were found in the 4000 subsequent blinded tests from 14 different international sources when patients with other cancers were included to prove that the discovered change was specific to breast cancer. As each new change was identified, further studies were undertaken to verify the specificity of each new change.

Professor Veronica James maintains that her results can be easily duplicated if the correct procedures are followed. Basically what Veronica is doing is taking a sample of skin, nail or hair and shining an x-ray beam through it. Upon examination of the x-ray one can observe rings which in their various positions indicate if the patient is developing a particular type of cancer. An absence of rings indicates the patient is healthy. Veronica claims that cancer can be detected very early using her method.

To see a short video with explanations of the test; Fiber Diffraction Diagnosis (FDD) with Prof Veronica James-Please visit the link below. ABC TV – Australia -“The Inventors”.

http://www.abc.net.au/tv/newinventors/txt/s2919200.htm

Research Gate – a portal for academic research lists 52 Publications for Professor James. Her areas of expertise include: Biological Physics, Medical Biochemistry: Proteins And Peptides (Incl. Medical Proteomics), Structural Chemistry And Spectroscopy, Physical Chemistry Of Materials, Medicinal & Bio-molecular Chemistry, Oncology & Carcinogenesis.

AWARDS: Prof James has an Order of Australia Medal for her services to the deaf. 1992 Quota South Pacific Breast Cancer Research Award, 1999 American Biographical Institute Woman of the Year and 2004 International Scientist of the Year IBC Cambridge. She has recently been awarded an honorary doctorate of Science from Cambridge.

There is an annual two day camp called the Veronica James Science Challenge for Hearing Impaired Children supported by the University of Sydney’s Faculty of Medicine through its department of pathology.

DOWNLOAD PUBLICATIONS:

1. extremely early diagnosis of prostate cancer veronica james – Prof Veronica James

2. The Connection Between Presence of Melanoma and changes in Fibre Diffraction Patterns Prof V James

Prof James has had a distinguished university teaching career progressing to Associate Professor, UNSW. She has been Visiting Fellow, Research School of Chemistry ANU, Visiting Fellow, Dep’t of Pathology UWA. Semi retired, she is presently Adjunct Professor, Research School of Chemistry ANU and wishes to continue cancer research to further develop her methods to help humanity. Thank you to Prof James for her permission to use her research and  images on this blog.

Until Next Time……..

Grace

Cancer Vaccines | A survivors story|From Cancer Good Things Grow Grace Gawler

I encored a recent interview with Jeffery Deslandes on my Voice America Internet radio show today for the Christmas period for a special reason. Because his story is both true and inspirational.

I encored a recent interview with Jeffery Deslandes on my Voice America Internet radio show today for the Christmas period for a special reason. Because his story is both true and inspirational. As Jeffrey quotes in his recently released ;  book; “From Cancer Good Things Grow”;  there are about 4,000 new cases of NHL each year in Australia. 1600 Australian die from NHL each year. If this were our road toll and there was an effective way of preventing deaths of even half of that number – there would be campaigns and lots of public and political interest. Why is there such little  interest in cancer immunotherapies? Jeffrey Deslandes is just one of many who have had success with vaccine treatments.

The questions begs – Have we become so conditioned to believing that cancer is a one-way ticket and there’s nothing we can do apart from try alternative medicine and throw out the “conventional medicine” baby with the bathwater?  Have we been convinced that conventional cancer medicine doesn’t work and that all big Jeffrey Deslandes Book 001pharma wants you to do is stay sick to garnish the pockets of doctors?  Have we bought into the rumour that the war on cancer is lost?  These are common statements from the Google cancer entrepreneurs whose aim is to convince patients to follow them, buy their “one size fits all” cancer products and……… take no responsibility for patient outcomes.

I know of far too many  patients who are not here to be with their families this Christmas because they used “faceless” advice from books, CDs or the internet – leaving aside treatable and potentially curable treatments for their cancer until it became obvious that their attempts to replicate the “cures” they have read about; ultimately failed them. This year I have experienced a new phenomenon, receiving many emails from parents who have taken the natural cancer “healing” path with their children using bizarre nutritional regimens, GcMAF, Budwig and Gerson Diets to name a few – most read about these treatments on blogs. Some of these children have been 3 and 5 years of age.  I try my best to influence them towards excellent sources of conventional medicine – but after a few emails – I never hear from them again. This is truly exasperating!!

Genuine, well documented  stories of cancer treatment successes are much needed. Such is the story of how Melbournian Jeffery Deslandes recovered from Stage 4 recurrent lymphoma that had grown resistant to conventional treatment found his remission – now eight and a half years clear. Jeffery did not seek Alternative medicine treatments when his lymphoma recurred again and again; rather he looked outside the conventional box to see what else science-based medicine could offer.

By purchasing Jeffrey Deslandes book (soft Cover /eBook) – you can help to promote the immune therapy he had right here in Australia. All proceeds go toward making this treatment more available for those in our region. PLEASE spread the good news. Vaccine therapies as immunotherapies go wider than just lymphoma. Successes are appearing from many cancer types including melanoma, prostate cancer and many more. If these therapies can be investigated alongside immune cycle research; we may indeed have a two incredibly power non invasive cancer treatment allies. Scroll to end of blog to see the effect of melanoma vaccine.**

Excerpts from Jeffrey Deslandes book “From Cancer Good things Grow”.

 

Chapter 7 -The cancer Returns Again and Again

Non-Hodgkin’s lymphoma is a bit like buffalo grass; it is hard to get out all of the roots and it tends to grow back. I had been informed that my cancer was incurable. It was a real shock at the time.
Non-Hodgkin’s lymphoma (NHL) is Australia’s fifth most common cancer, yet has a very low profile, compared to more publicised cancers such as breast, ovarian, bowel, melanoma and leukaemia. There are about 4,000 new cases of NHL each year in Australia, with about 1,600 deaths each year. That’s about the same as the National Road Toll in this country. Each year we spend billions trying to stop idiots killing each other on the road, yet comparatively little on a disease which is poorly understood. While Australia’s economy is soon to be taxed with the introduction of a Carbon Tax to combat Climate Change. Funny that, I have never known anyone who has died from Climate Change, but I have known scores and scores of people who have succumbed to cancer. We need Governments to spend serious money on cancer research.

After my cancer had returned for the fourth time in 2006, the next mainstream cancer treatment outlined by my specialist, was an autologous stem cell transplant. An autologous stem cell transplant, refers to your own body’s stem cells being first harvested, you are then given high-dose chemotherapy to hopefully kill all cancer in your body, and your stem cells

Jeffrey Deslandes
Jeffrey Deslandes

are then re-infused to build up your white cells, which have been decimated by the chemotherapy. The other option was an allogeneic stem cell transplant; the same procedure but the stem cells are used from a matched donor who is obviously free from cancer. However, for this we would need to find a matched donor, since my brother Ron was not a match, and other brother David was no longer with us. I decided not to take the recommendation of my highly trained lymphoma specialist. I decided that I would need to take charge of my treatment, and find something with a different mode of attack. If something is not working, you don’t keep hitting it with the same old stick! Read on,,,,,,,,

Chapter 8 – Vaccine Therapy–The New Beginning

Through my association with Lymphoma Australia, a fine not-for-profit organisation dedicated to raising awareness and supporting lymphoma patients, I became aware of work being done on vaccines for cancer treatment. This work was still experimental or being proven in clinical trials, but it was not quackery, it was being carried out by highly qualified haematologists and scientists.

My diseased lymph node, and my immature dendritic cells, were processed in the laboratory to manufacture a dendritic cell idiotype vaccine to fight the cancer. It is termed idiotype, because the vaccine is grown from my own cancer cells, and is thus specifically tailored to the idiosyncrasies of my cancer. It is worth noting that there are over 30 sub-types of lymphoma alone, and it is my understanding that each and every lymphoma is going to be somewhat different in its individual characteristics. By using my own lymphoma, we got a perfect match, the exact antibody to my cancer. The laboratory grew the vaccine formulation to make 33 doses of vaccine, which were stored at minus 196 °C in liquid nitrogen, and could be kept for perpetuity. Each dose of vaccine is about 1 ml, about a fifth of a teaspoon, but it contains about five million cells. Yes, that’s five million cells, each with a message for my immune system. The message was “this is what the cancer looks like, now do your job like you are supposed to, and go seek and destroy”.  Excerpt: “From Cancer Good Things Grow”

Help save a life ……… Readers of this blog – please help us to help others through cancer education. By passing on this blog or an episode from Voice America – you could also help cancer patients to re-frame their cancer experience and learn about the nature of cancer and how to outsmart it with science-based medicine.

May your Christmas season be filled with joy, love, passion and compassion….

Until next time….

Grace

**Warning:  Below – graphic image melanoma – positive results from repeated vaccine cancer treatments.

Conclusions: Prolonged, repetitive VMCL vaccination immunotherapy appears to be a clinically effective means
of generating relatively high CR rates, useful clinical responses and long-term survivals, with little toxicity, but
remains notably under-explored. Successive immunomodulation might explain the results. Closer analysis of
repetitive dosing is required.

Melanoma vaccines
Successful application of repeated dosing with Melanoma vaccines. Research- Brendon Coventry

Cancer Doesn’t Stop for Christmas | Dealing with the Challenges-Grace Gawler Voice America

Navigating the Cancer Maze represents the culmination of my 40 years experience working at the coalface of cancer in what I call cancer supportive care medicine. As a young girl of about 8 years of age – I had two ambitions in life; to research cancer or become a veterinary surgeon. The universe works in mysterious ways. In 1976 I married a veterinarian who had cancer.

LISTEN TO GRACE GAWLER  VOICE AMERICA AUDIO
Click headphones to listen to today’s show at Voice America

Today’s Navigating the Cancer Maze, covers several areas important to Cancer patients.

In addition to this blog – gracegawlermedia – on Sunday 21st December 2014 – I will be launching a new blockbuster or should I say myth-buster blog – Grace Gawler Blog: The Thinking Person’s Guide to the Truth behind Common Cancer Mythology.

Navigating the Cancer Maze represents the culmination of my 40 years experience working at the coalface of cancer in what I call cancer supportive care medicine. As a young girl of about 8 years of age – I had two ambitions in life; to research cancer or become a veterinary surgeon. The universe works in mysterious ways. In 1976 I married a veterinarian who had cancer.

It happened just a few days before Christmas in 1974 – 40 years ago when I had just turned 21. Suddenly I became a carer of a cancer patient who was my boyfriend and employer.

My wedding day 28 Feb 1976 - 21 years and full-time carer
My wedding day 28 Feb 1976 – 21 years and full-time carer

 Like many today I had no experience in how to cope personally or how to help the patient who was my charge. I had to improvise and learn along the way. Added to this, my boyfriend, who later became my husband when he was given a prognosis 6 weeks to live; was an amputee. He had lost his leg to bone cancer just after Christmas, January 1975. He survived, we had 4 children and now 4 grandchildren. I learned a lot during that “hands-on period” that added to later qualifications. My story of those times is recorded in my Memoirs: Grace Grit and Gratitude. (2008 – eBook available)

See You tube: Grace Grit and Gratitude  Also visit on the menu of this blog –  “Ian Gawler Cancer?”

Moving forward to 2012 I realised that consulting with patients and public speaking was not enough. With cancer incidence rising, what I had learned needed a Global voice; an opportunity to take what I had learned so far and add medical expertise in current cancer treatments and research combined with patients’ experiences.

Available eBook - buy soft cover Australia only
Available eBook – buy soft cover Australia only

Patient’s need reliable and genuine information when they are in the fight for their lives! 2014 marks 2 years on air with Voice America’s Health and Wellness Channel hosting ‘Navigating the Cancer Maze’. We want as many people as possible to know about Navigating the Cancer Maze internet radio because my Charity The Grace Gawler Institute sponsors this show to provide education and information free to all in need. Please visit the Website for our Christmas Fundraiser to support the show for 2015: “Move the World with Grace”

On this week’s pre-Christmas show I discuss key issues for cancer patients that have been highlighted by our guests on Navigating the Cancer Maze throughout 2014; a year of challenges and excitements in the Global Cancer Community. We will take a look at the impact of some of cancer’s entrepreneurs Including Wellness Warrior-Jess Ainscough, who has influenced many patients to follow the natural path to cancer healing, albeit encouraged by the Ian Gawler recovery story, which as you know, was highly likely to have been a misdiagnosis.

Unfortunately, but as expected; Jess’s Epithelioid sarcoma, a cancer that moves slowly has now progressed to a serious degree. Her mum recently died from breast cancer doing the same regimen. Entrepreneurial patients like Jess Ainscough have a huge influence on cancer patient’s treatment decisions. I truly despair at these stories. I hear from cancer patients like Jess daily and see them in my practice with the most horrendous fungating cancers that one would would expect to see in a third world country. I am passionate to educate cancer patients about the dangers of taking the 100% natural therapies approach. As a trained naturopath and herbalist-I am horrified by what I see hear and read about natural cancer cures!
More on this visit-Science -based Medicine Blog and See  Jessica Ainscough Wellness Warrior

Finally….Cancer Doesn’t Stop at Christmas:While for some this is a happy time of year – for others Christmas and New Year celebrations can be very a difficult & emotional time for those currently dealing with life challenging illness, including patients’ families. Also challenging is the person who may be missing from this year’s Christmas table. Please see helpful resources below – also listen to today’s show for helpful tips
Many of my Guests on Navigating the Cancer Maze have authored some fine books. I have listed them below. These are books of substance that contain valid and useful information for patients and families. Recommended for Christmas gifts or personal reading

Resources/Books mentioned on today’s show from my 2014 Guests:
BOOKS

  1. From Cancer Good Things Grow Jeffrey Deslandes – 8.5 year survivor of stage 4 lymphoma after failed treatments – 4 recurrences. Success with Dendritic cell vaccines. Pub  Balboa Pressall proceeds go to R& D Of DC Vaccines.
  2. “Three Months: A Caregiving Journey from Heartbreak to Healing” by Dietrich Stroeh Buy at Amazon
  3.  Recent Release-” Survivorship: Living Well During and After Cancer” by Dr Barrie Cassileth –
    Buy at:  http://www.cancercarestore.com/survivorship-living-well-during-and-after-cancer
  4. “Bad to the Bone: the True Story of David Tuccaro, Jr” – by David Tuccaro, Jr successful leukemia treatment- Buy at Amazon
  5. “Lead With Your Heart: Creating a Life of Love, Compassion, and Purpose”  by Regina Cates Buy at Amazon
  6. “The Man who Saved a Million Lives” – by Prof Ian Frazer Buy at Amazon
  7. Spontaneous Remission: An Annotated Bibliography by Caryle Hirshberg and Brendon O’Regan – Access this via IONS- Free chapter downloads:
    http://noetic.org/library/publication-books/spontaneous-remission-annotated-bibliography/

Movies:

Debbie Franke Ogg had a Hollywood Movie made about her life and recovery from Stage 4 Lymphoma. It starred Sam Neil and Anne Archer. First titled “A Leap of Faith” – the movie was later titled a “Question of Faith”. Debby is perhaps one of the few of millions who had a spontaneous remission from her cancer without medical treatment. The movie can be found online by typing the title into Google. Now a therapist in NY USA – Watch Movie online   Contact Debby.

Cancer Doesn’t Stop at Christmas: Help for those who may have lost a loved one this year. Resources provided by Beth O’Brien: a guest on this year’s Navigating the Cancer Maze.
http://seasonsofgrief.com.au/about-beth/
www.australiancelebrations.com.au
http://deathcafe.com/
https://www.suicidecallbackservice.org.au
http://www.livingisforeveryone.com.au
http://suicidepreventionaust.org/resources/
BOOK recommended by Beth:
Dying to be Free: A healing guide for families after a suicide (Beverly Cobain, Jean Larch) buy at Amazon
The Grief Recovery Handbook: The action program for moving beyond Death, Divorce and other losses by John W James and Russell Friedman Buy at Amazon

Listen to today’s show at
http://www.voiceamerica.com/episode/82356/cancer-doesnt-stop-for-christmas-dealing-with-the-challenges

Join Voice America for free: http://www.voiceamerica.com/member/register

OR Join this blog for weekly updates delivered to your email box.

Until next time – Compliments of the Christmas Season

Grace

Options, Choices and Treatments for Cancer Recovery| Navigating the Cancer Maze

New cancer treatments are always controversial; BUT – this method is not a treatment. It’s a smart approach. A Smart approach that utilizes all that we know so far about cancer. It works because ultimately; our innate immune system knows what to do.

Options, Choices and Treatments for Cancer Recovery: De mystifying the oscillating the immune cycle.

When my ex husband and I had the idea for starting support groups for cancer patients in the early 1980’s. cancer organizations, patients and doctors were initially not supportive. In fact they were skeptical. They could not see any possible therapeutic benefit could come from people attending a support group.  How wrong they were! Move forward Body rhythms diagram40 years! Yes this December marks my beginning working with cancer patients 40 years ago in a time when there was no support in the health system and no support groups. Now, the benefit of patients attending structured supports and the well being benefit is indisputable.

There are still many new areas to explore, which leads me to discussing the immune cycle. It would seem that during 2014 on Navigating the Cancer Maze – we uncovered and delivered some significant “missing” pieces of the cancer treatment puzzle. It is my hope that as 2014 comes to an end – that 2015 will truly usher in a new paradigm in cancer treatments. The foundation has been laid, extensive research already done, the concept has been introduced worldwide – the  immune cycle measurement is here – NOW!
Now it is up to cancer patients to prove Martin Ashdown and Brendon Coventry right….or wrong. I liked it when Martin Ashdown said – “We believe this is so, a breakthrough – but we are open to being proven wrong!” As in the early days of my first charitable  foundation – it was people power – patient power that made a difference to the success of the Cancer Support Group Movement. Once told there would likely be a measured benefit from attending a support group – the press broadcast the news and the patients came on board en masse!

New cancer treatments are always controversial; BUT – this method is not a treatment. It’s a smart approach. A Smart approach that utilizes all that we know so far about cancer. It works because ultimately; our innate immune system knows what to do. It is just in temporary overwhelm. So doesn’t it make perfect sense that to find the best time to work in synch within the cycle of each person’s immune system to add the best chemotherapy or monoclonal antibody or other targeted treatment. Isn’t this the personalized approach we have been searching for? We all thought it would come in a pill – not an approach and that’s a paradigm shift that some in the world of science and medicine are struggling with.

measuring immune cycleKnowing how one’s immune cycle oscillates holds a clue, “the missing link” that can direct doctors to seek the best time to treat patients in their personal window of opportunity. Then within the parameters of what we know they will have the best chance of a good response or complete response to treatment. (CR)

When cancer cells challenge us – they are also smart. They are a part of us created by our internal systems. You could define cancer as an internal systems error!  These cancer cells cleverly recruit our intelligent mechanisms using them for their own growth and survival. It seems a bit crazy that something that wants to survive – kills its host. But – that’s life! To listen to the latest Voice America related to this blog visit:
http://www.voiceamerica.com/episode/82056/options-choices-and-treatments-for-cancer-recovery

So – I believe as do Ashdown and Coventry – that if there is enough of the immune response left in a patient – that the cycle can still be measured and timed so administer the right treatment at the right time. It is simple enough – the only real cost being a series of blood tests. Then finding a doctor who will look at the science and research and say yes – they administer treatment during the 12 hour window of opportunity. The Grace Gawler Institute is keen to let you know and experience the immune cycle for yourself. Please Read more below or join the immune cycle registry at:

http://www.gracegawlerinstitute.com/immune-cycle-registry/ also see our Next “Survivor Academy” Course!

Martin Ashdown and Brendon Coventry have built upon earlier excellent work in the study of chronobiology: Below are references given on Navigating the Cancer Maze today: I have provided abstract content as well as links.

Until next time……Grace

  • Annu Rev Pharmacol Toxicol. 2010;50:377-421. doi: 10.1146/annurev.pharmtox.48.113006.094626.
    Circadian timing in cancer treatments.
    Lévi F1, Okyar A, Dulong S, Innominato PF, Clairambault J.
    Author information
    Abstract
    The circadian timing system is composed of molecular clocks, which drive 24-h changes in xenobiotic metabolism and detoxification, cell cycle events, DNA repair, apoptosis, and angiogenesis. The cellular circadian clocks are coordinated by endogenous physiological rhythms, so that they tick in synchrony in the host tissues that can be damaged by anticancer agents. As a result, circadian timing can modify 2- to 10-fold the tolerability of anticancer medications in experimental models and in cancer patients. Improved efficacy is also seen when drugs are given near their respective times of best tolerability, due to (a) inherently poor circadian entrainment of tumors and (b) persistent circadian entrainment of healthy tissues. Conversely, host clocks are disrupted whenever anticancer drugs are administered at their most toxic time. On the other hand, circadian disruption accelerates experimental and clinical cancer processes. Gender, circadian physiology, clock genes, and cell cycle critically affect outcome on cancer chronotherapeutics. Mathematical and systems biology approaches currently develop and integrate theoretical, experimental, and technological tools in order to further optimize and personalize the circadian administration of cancer treatments.
    PMID:
    20055686
    [PubMed – indexed for MEDLINE]
  • http://www.ncbi.nlm.nih.gov/pubmed/20055686

Ann Pharm Fr. 2008 Jun;66(3):175-84. doi: 10.1016/j.pharma.2008.05.003.
[The circadian-timing system: a determinant of drug activity and a target of anticancer treatments].
[Article in French]
Lévi F.
Author information
Abstract
Cellular proliferation and drug detoxification are controlled over the 24h by the circadian-timing system, whose disruption can favor malignant processes. Thus, prolonged shift work appears to increase the risk of breast, colon or prostate cancer. Alterations in circadian physiology and/or molecular-clock genes accelerate cancer progression in experimental models and in cancer patients. In addition, anticancer treatments can also dampen or reinforce the circadian-timing system, as a function of dose and time of administration. The adjustment of anticancer-drug delivery to the circadian-timing system (chronotherapeutics) has allowed to reduce five-fold the incidence of severe adverse events as compared to constant rate infusion or wrongly-timed chronomodulated delivery in cancer patients. In experimental models, the best antitumor efficacy is usually obtained following treatment delivery near the least toxic time, a statement that also seems to apply to patients. Dedicated technologies include programmable in time pumps and rhythm monitors and are required for chronotherapeutics. Recent results have revealed that the optimal chronotherapeutic schedule could differ as a function of gender and circadian physiology. In conclusion, the circadian-timing system was shown to negatively control malignant proliferation via partly identified molecular mechanisms. The components of the circadian-timing system thus constitute new potential therapeutic targets in oncology. Mathematical models help toward a better understanding of the role of variability for the determination of the optimal chronotherapeutic schedule and constitute useful tools for the personalization of cancer chronotherapeutics.

http://www.ncbi.nlm.nih.gov/pubmed/18706346

Handb Exp Pharmacol. 2013;(217):261-88. doi: 10.1007/978-3-642-25950-0_11.
Cancer chronotherapeutics: experimental, theoretical, and clinical aspects.
Ortiz-Tudela E1, Mteyrek A, Ballesta A, Innominato PF, Lévi F.
Author information
Abstract
The circadian timing system controls cell cycle, apoptosis, drug bioactivation, and transport and detoxification mechanisms in healthy tissues. As a consequence, the tolerability of cancer chemotherapy varies up to several folds as a function of circadian timing of drug administration in experimental models. Best antitumor efficacy of single-agent or combination chemotherapy usually corresponds to the delivery of anticancer drugs near their respective times of best tolerability. Mathematical models reveal that such coincidence between chronotolerance and chronoefficacy is best explained by differences in the circadian and cell cycle dynamics of host and cancer cells, especially with regard circadian entrainment and cell cycle variability. In the clinic, a large improvement in tolerability was shown in international randomized trials where cancer patients received the same sinusoidal chronotherapy schedule over 24h as compared to constant-rate infusion or wrongly timed chronotherapy. However, sex, genetic background, and lifestyle were found to influence optimal chronotherapy scheduling. These findings support systems biology approaches to cancer chronotherapeutics. They involve the systematic experimental mapping and modeling of chronopharmacology pathways in synchronized cell cultures and their adjustment to mouse models of both sexes and distinct genetic background, as recently shown for irinotecan. Model-based personalized circadian drug delivery aims at jointly improving tolerability and efficacy of anticancer drugs based on the circadian timing system of individual patients, using dedicated circadian biomarker and drug delivery technologies.
http://www.ncbi.nlm.nih.gov/pubmed/23604483

Chronobiol Int. 2002 Jan;19(1):1-19.
From circadian rhythms to cancer chronotherapeutics.
Lévi F.
Author information
Abstract
Mammalian circadian rhythms result from a complex organization involving molecular clocks within nearly all “normal” cells and a dedicated neuroanatomical system, which coordinates the so-called “peripheral oscillators.” The core of the central clock system is constituted by the suprachiasmatic nuclei that are located on the floor of the hypothalamus. Our understanding of the mechanisms of circadian rhythm generation and coordination processes has grown rapidly over the past few years. In parallel, we have learnt how to use the predictable changes in cellular metabolism or proliferation along the 24h time scale in order to improve treatment outcome for a variety of diseases, including cancer. The chronotherapeutics of malignant diseases has emerged as a result of a consistent development ranging from experimental, clinical, and technological prerequisites to multicenter clinical trials of chronomodulated delivery schedules. Indeed large dosing-time dependencies characterize the tolerability of anticancer agents in mice or rats, a better efficacy usually results from treatment administration near the least toxic circadian time in rodent tumor models. Programmable in time multichannel pumps have allowed to test the chronotherapy concepts in cancer patients and to implement chronomodulated delivery schedules in current practice. Clinical phase I and II trials have established the feasibility, the safety, and the activity of the chronotherapy schedules, so that this treatment method has undergone further evaluation in international multicenter phase III trials. Overall, more than 2,000 patients with metastatic disease have been registered in chronotherapy trials. Improved tolerability and/or better antitumor activity have been demonstrated in randomized multicenter studies involving large patient cohorts. The relation between circadian rhythmicity and quality of life and even survival has also been a puzzling finding over the recent years. An essential step toward further developments of circadian-timed therapy has been the recent constitution of a Chronotherapy cooperative group within the European Organization for Research and Treatment of Cancer. This group now involves over 40 institutions in 12 countries. It is conducting currently six trials and preparing four new studies. The 19 contributions in this special issue reflect the current status and perspectives of the several components of cancer chronotherapeutics.
PMID:
11962669
[PubMed – indexed for MEDLINE]

http://www.ncbi.nlm.nih.gov/pubmed/11962669
Cancer Causes Control. 2006 May;17(4):611-21.
Chronotherapeutics: the relevance of timing in cancer therapy.
Lévi F.
Author information
Abstract
BACKGROUND:
Cell physiology is regulated along the 24-h time scale by a circadian timing system composed of molecular clocks within each cell and a central coordination system in the brain. The mammalian molecular clock is made of interconnected molecular loops involving at least 12 circadian genes. The cellular clocks are coordinated by the suprachiasmatic nuclei, a hypothalamic pacemaker which also helps the organism adjust to environmental cycles. The rest-activity rhythm is a reliable marker of the circadian system function in both rodents and man. This circadian organization is responsible for predictable changes in the tolerability and efficacy of anticancer agents, and possibly also in tumor promotion or growth.
METHODS:
Expected least toxic times of chemotherapy were extrapolated from experimental models to human subjects with reference to the rest-activity cycle. The clinical relevance of the chronotherapy principle, i.e. treatment administration as a function of rhythms, has been demonstrated in randomized multicenter trials.
RESULTS:
Chronotherapeutic schedules have been used to safely document the activity of the association of oxaliplatin, 5-FU and leucovorin against metastatic colorectal cancer and to set up a new medicosurgical management of this disease which achieved unprecedented long term survival.
CONCLUSION:
The chronotherapy concept offers further promises for improving current cancer treatment options as well as for optimizing the development of new anticancer or supportive agents.
PMID:
16596317
[PubMed – indexed for MEDLINE]

Mol Med. 2012 Dec 6;18:1249-60. doi: 10.2119/molmed.2012.00077.
Circadian rhythm disruption in cancer biology.
Savvidis C1, Koutsilieris M.
Author information
Abstract
Circadian rhythms show universally a 24-h oscillation pattern in metabolic, physiological and behavioral functions of almost all species. This pattern is due to a fundamental adaptation to the rotation of Earth around its own axis. Molecular mechanisms of generation of circadian rhythms organize a biochemical network in suprachiasmatic nucleus and peripheral tissues, building cell autonomous clock pacemakers. Rhythmicity is observed in transcriptional expression of a wide range of clock-controlled genes that regulate a variety of normal cell functions, such as cell division and proliferation. Desynchrony of this rhythmicity seems to be implicated in several pathologic conditions, including tumorigenesis and progression of cancer. In 2007, the International Agency for Research on Cancer (IARC) categorized “shiftwork that involves circadian disruption [as] probably carcinogenic to humans” (Group 2A in the IARC classification system of carcinogenic potency of an agent) (Painting, Firefighting, and Shiftwork; IARC; 2007). This review discusses the potential relation between disruptions of normal circadian rhythms with genetic driving machinery of cancer. Elucidation of the role of clockwork disruption, such as exposure to light at night and sleep disruption, in cancer biology could be important in developing new targeted anticancer therapies, optimizing individualized chronotherapy and modifying lighting environment in workplaces or homes.
PMID:
22811066
[PubMed – indexed for MEDLINE]
PMCID:
PMC3521792
Free PMC Article

Chronobiol Int. 2012 Apr;29(3):227-51. doi: 10.3109/07420528.2012.658127.
Clock genes and clock-controlled genes in the regulation of metabolic rhythms.
Mazzoccoli G1, Pazienza V, Vinciguerra M.
Author information
Abstract
Daily rotation of the Earth on its axis and yearly revolution around the Sun impose to living organisms adaptation to nyctohemeral and seasonal periodicity. Terrestrial life forms have developed endogenous molecular circadian clocks to synchronize their behavioral, biological, and metabolic rhythms to environmental cues, with the aim to perform at their best over a 24-h span. The coordinated circadian regulation of sleep/wake, rest/activity, fasting/feeding, and catabolic/anabolic cycles is crucial for optimal health. Circadian rhythms in gene expression synchronize biochemical processes and metabolic fluxes with the external environment, allowing the organism to function effectively in response to predictable physiological challenges. In mammals, this daily timekeeping is driven by the biological clocks of the circadian timing system, composed of master molecular oscillators within the suprachiasmatic nuclei of the hypothalamus, pacing self-sustained and cell-autonomous molecular oscillators in peripheral tissues through neural and humoral signals. Nutritional status is sensed by nuclear receptors and coreceptors, transcriptional regulatory proteins, and protein kinases, which synchronize metabolic gene expression and epigenetic modification, as well as energy production and expenditure, with behavioral and light-dark alternance. Physiological rhythmicity characterizes these biological processes and body functions, and multiple rhythms coexist presenting different phases, which may determine different ways of coordination among the circadian patterns, at both the cellular and whole-body levels. A complete loss of rhythmicity or a change of phase may alter the physiological array of rhythms, with the onset of chronodisruption or internal desynchronization, leading to metabolic derangement and disease, i.e., chronopathology.
PMID:
22390237
[PubMed – indexed for MEDLINE]

Listen to Your Body Clock – Cancer and Your Health – Grace Gawler

We have knowledge of many cycles in our world. The tides, day and night are the most obvious. All creatures great and small are subject to these unseen forces that ultimately shape our life and our experience of it.” The circadian clock in mammals drives many physiological processes including the daily rhythms of sleep–wake behaviour, hormonal secretion, and metabolism. Less known, is that the clock also drives our immune cycles; an important factor in cancer treatment and recovery says Melbourne University Research Fellow Martin Ashdown, who has studied the phenomena for a long time. The science of taking advantage of the body’s own immune rhythm to improve efficacy of treatments is worth paying attention to whether its surgery, chemotherapy, immunotherapies, radiation/cyberknife; one thing is now clear – timing of treatment matters!

Research work of Synchronizing cancer treatment with the patient’s immune cycle has been recently launched into our awareness by Martin Ashdown and Brendon Coventry – and hopefully this blog, and my radio show Navigating the Cancer Maze on Voice America’s Health and Wellness Channel. Please spread the news!

With regards to timing – Did you know that majority of best-selling drugs in the United States target circadian gene products? Consider the case of statins, a class of drug that lowers cholesterol by inhibiting HMGCR (HMG-CoA reductase). HMGCR is the rate-limiting enzyme in cholesterol biosynthesis and its activity peaks during the night. Statins with short half lives showed maximal efficacy when taken in the evening (when their target gene was most active).This is just one example of chronotherapeutic practices positively impacting drug treatment. In other words – it’s all in the timing. (see resources below for more information on this).

In terms of Circadian rhythms and body clocks – simply reconsider an old message for good health. Early to bed and early to rise makes a man healthy, wealthy and wise!”

Take a look at the following diagram ( source Scientific American) to see what your body clock is doing – and at what time!

Circadian-rhythm-chart-on-physiologyBody clocks–-circadian rhythms—health; has been a hobby–horse of mine for some years. I am widely read on the subject and back more than 20 years ago – it became clear to me that there were tremendous health connections and implications for health and wellbeing and disease prevention – not only treating disease once it is evident.

So here is a Window of Opportunity for you
Readers of this blog – I invite you to stop for a moment and consider how your body clock affects your life. Is it possible to make some simple changes IN TERMS OF TIME & TIMING?

Do you listen to your body clock or constantly override it? Those of us who are disease free have the luxury of change and can enjoy the consequences-improved health. We don’t even have to have an immune cycle test – we SIMPLY NEED TO BECOME MORE AWARE of living in synch with ourselves and who and what is around us. It is the only real power that we have.

Being aware of your body clock and timing in your world, has one enormous benefit and this is also useful for anyone GG and Martin AShdown 31 Oct 14 interview  - Copy (2)dealing with a diagnosis of cancer – It brings you more into conscious connection with your body. Many patients over the past 40 years have told me that this is an unexpected gift that cancer brought to their lives. Some could view it as an opportunity for changing lifestyle, jobs etc…In terms of timing – the question begs what has happened in this person’s life that has perhaps interfered with their personal body clock? What could have caused a highly synchronized system to go into cellular chaos? These are big questions – but then again cancer is a big illness!
Left  Martin Ashdown and me – Grace Gawler.

Visit http://www.gracegawlerinstitute.com/immune-cycle-registry/ to join our exploratory pilot study -Measure your immune system.

A paper published by Department of Cellular and Structural Biology, UT Health Science CenterSan Antonio, Texas, USA; 2Department of Internal Medicine, Thuringia, Saalfeld, Germany; 3Department of Physiology, Jagiellonian University Medical College, Cracow, Poland states:

“There is a vast amount of literature suggesting that the photo-periodic environment (day/night) influences the incidence of cancer. While an association of chrono-disruption was initially proposed only for breast cancer, we recently suggested a more general theory, i.e., chrono-disruption may aggravate the development of many cancer types.”

Knowledge is power and knowledge of not only your body clock – but that of other mammals and nature. It’s all in the timing! Women’s’ menstrual cycle is perhaps the obvious one we know about. In nature – just watch a David Attenborough documentary to see the wonder of timing in nature!

We have knowledge of many cycles in our world. The tides, day and night are the most obvious. All creatures great and small are subject to these unseen forces that ultimately shape our life and our experience of it.” The circadian clock in mammals drives many physiological processes including the daily rhythms of sleep–wake behaviour, hormonal secretion, and metabolism.

Less known, is that the clock also drives our immune cycles; an important factor in cancer treatment and recovery says Melbourne University Research Fellow Martin Ashdown, who has studied the phenomena for a long time. The science of taking advantage of the body’s own immune rhythm to improve efficacy of treatments is worth paying attention to whether its surgery, chemotherapy, immunotherapies, radiation/cyberknife; one thing is now clear – timing of treatment matters! There is a window of opportunity within the 7 day cycle, Listen to Martin Ashdown to hear the story of how TIMING MATTERS!
Following on – some interesting articles and resources that relate to our body clock.

  • Complete clinical responses to cancer therapy caused by multiple divergent approaches a repeating theme lost in translation
    Coventry BJ1, Ashdown ML.1Discipline of Surgery, University of Adelaide, Royal Adelaide Hospital and Faculty of Medicine, University of Melbourne, Australia.
    SOURCE: http://www.ncbi.nlm.nih.gov/pubmed/22740774
  • Window of Opportunity – Martin Ashdown and Brendon Coventry:

          SOURCE:   http://www.immunaid.com.au/download/pressreviews_2014053001.pdf

  • The Clock Is Off: Bipolar Disorder and Circadian Rhythm – Scientific American – Apr 1, 2010 By Monica Heger
    Bipolar disorder may be linked to mutations affecting circadian rhythm
    |By Monica Heger
    “An off-kilter body clock can throw off our sleep-wake cycle, eating habits, body temperature and hormones—and mounting evidence suggests a malfunctioning clock may also underlie the mood cycles in bipolar disorder. In a new study led by psychiatrist Alexander Niculescu of Indiana University, researchers found that children with bipolar disorder were likely to have a mutated RORB gene, which codes for a protein crucial to circadian clock function.”
    Source: http://www.scientificamerican.com/article/the-clock-is-off/

Circadian gene expression atlas in mammals: Implications for biology and medicine
Ray Zhanga,1, Nicholas F. Lahensa,1, Heather I. Ballancea, Michael E. Hughesb,2, and John B. Hogenescha,2
Department of Pharmacology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104; and bDepartment of Biology, University of Missouri, St. Louis, MO 63121

“We generated high-resolution multi-organ expression data showing that nearly half of all genes in the mouse genome oscillate with circadian rhythm somewhere in the body. Such widespread transcriptional oscillations have not been previously reported in mammals. Applying pathway analysis, we observed new clock-mediated spatiotemporal relationships. Moreover, we found a majority of best-selling drugs in the United States target circadian gene products. Many of these drugs have relatively short half-lives, and our data predict which may benefit from timed dosing.”

Source:  http://www.pnas.org/content/111/45/16219.abstract

For the more scientifically minded – don’t be put off by the title!

The Photoperiod, Circadian Regulation and Chronodisruption: The Requisite Interplay Between The Suprachiasmatic Nuclei and The Pineal And Gut Melatonin:

1Department of Cellular and Structural Biology, UT Health Science CenterSan Antonio, Texas, USA; 2Department of Internal Medicine, Thuringia, Saalfeld, Germany; 3Department of Physiology, Jagiellonian University Medical College, Cracow, Poland

“Part of their conclusion is that “Circadian rhythmicity is an integral component of normal and optimal physiology. Not only the SCN, but cells throughout the organism are equipped with internal clocks that control the molecular events that occur during each 24-hour period. These events appear to be precisely timed and in modern societies the intrinsic time keepers are provided with misinformation which, when prolonged, likely has ramifications in terms of increased pathologies.

It would seem judicious to take better care of the circadian network by providing appropriate photoperiodic cues, which currently seemed to be almost totally ignored. In addition, large amounts of this indoleamine (melatonin) is produced in the mucosa of GIT that seems to serve as local antioxidant and protective substance for the gut and liver against a variety of noxious agents, particularly the bacteria and their toxins, introduced into the gut with each meal.

There is a vast amount of literature suggesting that the photoperiodic environment influences the incidence of cancer. While an association of chronodisruption was initially proposed only for breast cancer, we recently suggested a more general theory, i.e., chronodisruption may aggravate the development of many cancer types.”
Source: http://www.ncbi.nlm.nih.gov/pubmed/21893686

Happy reading! Remember to visit our website: http://www.gracegawlerinstitute.com/immune-cycle-registry/

Until next time ………Grace

An Answer to Cancer – How Your Immune Body-Clock can assist Complete Remission | Navigating the Cancer Maze

Cancer affects everyone around the world in some way. Friends, relatives, children, mums and dads, grans and grandpas! It does not discriminate. It causes as much or perhaps even more misery than war because it reaches into every race, culture and country! If there was just one thing we could add to the recipe for Curing cancer or extending life with quality and well-being – wouldn’t we all be excited and interested?Do you want to know one important missing piece of the cancer puzzle? Two cancer researchers Martin Ashdown & Brendon Coventry have explored that question and yes they are excited!

How Your Immune Body-Clock can assist Complete Remission: (Please pass on the link to this blog to those in need)

Cancer affects everyone around the world in some way. Friends, relatives, children, mums and dads, grans and grandpas! It does not discriminate. It causes as much or perhaps even more misery than war because it reaches into every race, culture and country!  If there was just one thing we could add to the recipe for Curing cancer or extending life with quality and well-being – wouldn’t we all be excited and interested? Do you want to know one important missing piece of the cancer puzzle?  Listen to today’s show at: http://www.voiceamerica.com/episode/81479/an-answer-to-cancer-how-your-immune-body-clock-can-assist-complete-remission

Measuring immune cycles
Measuring immune cycles may be one missing piece of the cancer cure puzzle!

The show is free to air on the internet – live streaming listening at any time- free download – archived indefinitely.

Two cancer researchers Martin Ashdown & Brendon Coventry have explored that question and yes they are excited! So am I and so are some doctors and oncologists! Testing patients to map their immune cycle is not a complex exercise, but to do this, a system needs to be changed. All discoveries of worth seem to be hobbled for while – then accepted – struggling across the finish line…sometime after decades!

In 1983, Australian doctors J. Robin Warren and Barry Marshall isolated Helicobacter pylori, the bacterial cause of peptic ulcer disease. When the H. pylori hypothesis was developed, the doctors were certain that it would immediately gain universal acceptance and that within two years peptic ulcer therapy would be essentially an antimicrobial regimen”. This was far from the case. A 1986 book on Peptic Ulcer and its Drug Causation lends a page to the bacterial hypothesis, noting, “Whether these bacteria have an aetiological role in peptic ulcer gastritis is unknown”. At this time, doctors still prescribed drugs to reduce stomach acidity and monitored patients for complications. The story of Helicobacter pylori’s acceptance as a pathogenic agent reveals the issues with the acceptance of new thought even when there is validation and justification. http://www.jyi.org/issue/delayed-gratification-why-it-took-everybody-so-long-to-acknowledge-that-bacteria-cause-ulcers/

There are ethical laws in place; essential for the safety of humans in medicine. Changed laws of medical ethics, prevent a modern reprise of Pasteur’s heroic demonstration of his rabies vaccine through the vaccination of an infected boy. Measuring each cancer patients immune cycle and timing their treatment at the right time –  is nothing akin to that! It simply makes sense!

Perhaps one can understand the caution in prescribing an antibiotic. Measuring immune cycles and timing treatment for a better outcome? Now to my way of thinking this fulfills the old Hippocratic oath – “Above all, do no harm!”

The Grace Gawler Institute has a history of wanting to procure the best treatment options for cancer patients. We feel that by educating patients about their immune cycle and taking this material to their doctor – they can help change the face of cancer treatment in a risk free experiment to prove (or not) the research work of Martin Ashdown & Brendon Coventry.  This is why we have created the Cancer Immune Registry:

world cancer
Cancer affects everyone around the globe- it does not discriminate!

Background –  A cancer drug used for more than 20 years that is now providing oncologists with new information about how to best help patients achieve complete remission. The drug called interleukin-2, is providing cancer researchers with something akin to how the “Rosetta Stone” was used to unlock historical script; the outcome; mapping the immune cycle!

To understand how this is possible – join me with guest Martin Ashdown on Navigating the Cancer Maze on Voice America’s Health and Wellness channel ( internet radio)  to hear the full story of this amazing breakthrough.

Learn how you can access info about your immune cycle to assist cancer treatment efficacy.

RESOURCES:

1. http://www.voiceamerica.com/episode/81479/an-answer-to-cancer-how-your-immune-body-clock-can-assist-complete-remission

2. http://www.gracegawlerinstitute.com/immune-cycle-registry/

3. Martin Ashdown Window of Opportunity1 article: Australasian Science

4. MARTIN ASHDOWN A Matter of Time_AS_Article: article Australasian Science

5. VIDEO: Treatment of Metastatic Melanoma: Could Timing Be Everything? http://www.youtube.com/watch?v=yXX-9t8xiAo

6. CLICK  HERE FOR PRESS RELEASE VOICE AMERICA

7. CLICK HERE FOR VOICEAMERICA PRESS PASS RELEASE

An Answer to Cancer – How Your Immune Body-Clock can assist Complete Remission Grace Gawler with Martin Ashdown

Could timing of cancer treatments be the missing link in delivery of cancer therapies? Sounds too simple to be true? Two cancer researchers Martin Ashdown & Brendon Coventry are “immunological explorers” who not only unearthed a buried “treasure”; but they have also created a map for other innovative cancer “explorers” to follow. The “treasure” is a cancer drug used for more than 20 years that is now providing oncologists with new information about how to best help patients achieve complete remission. The drug called interleukin-2, is providing cancer researchers with something akin to how the “Rosetta Stone” was used to unlock historical script; the outcome; mapping the immune cycle!

An Answer to Cancer – How Your Immune Body-Clock can assist Complete Remission

Be sure to mark this coming weekend in your diary (7,8 November) to listen to this inspiring and significant edition of Navigating the Cancer Maze.

The Cancer Immune Cycle - A Window of Opportunity in Treatment Efficacy
The Cancer Immune Cycle – A Window of Opportunity in Treatment Efficacy

The show can be downloaded on itunes or reached at any time live streaming at the link below.
http://www.voiceamerica.com/episode/81479/an-answer-to-cancer-how-your-immune-body-clock-can-assist-complete-remission

The show is broadcast by Voice America on internet radio – but is distributed world wide and is a must for all cancer patients. Please select link at bottom of page to be directed to the eCard for this weeks edition. You can also sign up with Voice America to receive notice of ongoing shows. You can also sign up and follow this blog ( in the right side bar)  to receive weekly invaluable cancer information and Navigating the Cancer Maze links direct to your email inbox.

We know you will be inspired and encouraged by this show – so we have a call to action page on our website where cancer patients can be involved.

To join or read about the Cancer Immune Cycle Registry
please visit: http://www.gracegawlerinstitute.com/immune-cycle-registry/

 

This week……..An Answer to Cancer – How Your Immune Body-Clock can assist Complete Remission

Could timing of cancer treatments be the missing link in delivery of cancer therapies? Sounds too simple to be true? Two cancer researchers Martin Ashdown & Brendon Coventry are “immunological explorers” who not only unearthed a buried “treasure”; but they have also created a map for other innovative cancer “explorers” to follow. The “treasure” is a cancer drug used for more than 20 years that is now providing oncologists with new information about how to best help patients achieve complete remission. The drug called interleukin-2, is providing cancer researchers with something akin to how the “Rosetta Stone” was used to unlock historical script; the outcome; mapping the immune cycle! Join me with guest Martin Ashdown on Navigating the Cancer Maze to hear the story of this amazing breakthrough. Learn how you can access info about your immune cycle to assist cancer treatment efficacy.            Please Remember to like us on Facebook!

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