Giulia Enders has been fascinated with the human digestive system and how its function affects all aspects of our health. In this extract of her newly published book, Gut: The Inside Story of Our Body’s Most Under-rated Organ,she discusses the surprisingly complex end point of digestion.
Giulia Enders, a young passionate medical PhD student has been fascinated with the human digestive system and how its function affects all aspects of our health. In her newly published book, Gut: The Inside Story of Our Body’s Most Under-rated Organ, she discusses the surprisingly complex end point of digestion. Did you know that 80% of your immune system is located in your GUT? It is not rocket science to make the link between having a healthy gut and good health and wellbeing! Giulia Enders brings this complex subject to an almost lighthearted but powerful narrative that is engaging, entertaining and incredibly valuable for anyone interested in improving their wellbeing.
Listen to interview on Radio National Giulia Enders with Natasha Mitchell:
From my personal viewpoint; I have always been fascinated by the gut and it’s workings. I became even more fascinated when I surgically parted with 10 feet of intestine (both small and large intestine) in a series of surgeries over a 13 year period. Re-framing the experience as a learning opportunity; a result of a medical misadventure rather than disease; I was thrown into the fast track of helping to convince my body that less was now going to be more!
How would or could my gut adapt to such huge changes and what did I have to do to help the process. My gut became an intense “in house” study for me so when I heard this terrific interview on Radio National last week – I just had to share it with all of you who want to look after your health -including your inner gut health. Read an edited extract of Giulia Enders book’ ‘Gut: The Inside Story of Our Body’s Most Under-rated Organ’, published by Scribe. Select the link below to Radio National.
About the author Giulia Enders: When she was seventeen, Giulia developed a sore on her leg that stubbornly refused to disappear.Soon other sores appeared on her body and despite the efforts of a range of doctors and medications, nothing seemed to help them heal. So she did some research. She read about other similar cases that had followed courses of antibiotics. She began to make a link between her skin’s condition and the health of her intestines. Her fascination with the gut and how its function affects all kinds of aspects of our health continued, so she started studying medicine and continued researching for her PhD.
The result is a MUST READ for anyone interested in improving their health. An international best-seller: Gut: the inside story of our body’s most under-rated organ just published in Australia.
Once you read this book, I think you will appreciate your own inside story and, maybe even make some health enhancing “gut-sense” lifestyle changes!
According to Jean Connors, MD and medical director of Anticoagulation Management Services at Brigham and Women’s Hospital and Dana-Farber Cancer Institute; Cancer patients are at a higher risk than the general population of developing serious blood clots, including deep vein thrombosis (DVT) in the legs or pulmonary emboli in the lungs, which can be fatal.
Navigating the Vascular Maze in Cancer Medicine– Interview with vascular surgeon (now retired) Dr John Singe. To further this conversation I have added a number of resources and what I believe is very helpful information for anyone interested in health and wellbeing and disease prevention.
According to Jean Connors, MD and medical director of Anticoagulation Management Services at Brigham and Women’s Hospital and Dana-Farber Cancer Institute; Cancer patients are at a higher risk than the general population of developing serious blood clots, including deep vein thrombosis (DVT) in the legs or pulmonary emboli in the lungs, which can be fatal.
“Of all the blood clots detected, 20 percent of them are detected in people who have cancer,” She says. Individuals over the age of 60 are at the highest risk of developing blood clots.
“There is a balance in the body between pro-clotting and anti-clotting activity,” says Connors. ”Cancer skews the balance in terms of pro-clotting, increases inflammation, and compresses blood vessels, all risk factors for developing clots.”
As well as a tendency to coagulate or clot; treatments for cancer or blood disorders can also affect the balance of pro and anti-clotting factors.
Immobility and increased bed rest during treatment also enhances a patient’s risk of developing a hyper coagulant state this is why many hospital patients are treated with heparin or some form of anti-coagulant medicine. When seated in a car or aeroplane for long periods of time, it is important to change position, take short walks when possible to keep your blood flowing and practice the simple exercise talked about in today’s interview on Navigating the Cancer Maze Select the title to be redirected to my internet radio show on Voice America’s Health and Wellness Channel. (Free to listen live streaming or to download on itunes.) http://www.voiceamerica.com/episode/84200/special-encore-presentation-navigating-the-vascular-maze-in-cancer-medicine-clotting-risks-for
Patient risk of DVT and embolisms increases enormously with air travel to overseas cancer clinics and in my experience; the issue is often not addressed with diagnostic measures or treatment at these clinics. Unfortunately I have seen this scenario many times including when cancer patients are informed of the risks but are dedicated to a “natural cancer therapies” approach. These patients left their Clexane injections in their luggage to be considered for use at a later date. Cancer did not take their lives. Too many died as a result of DVT and resultant embolisms.
Of course if you have had DVT, embolisms or blood coagulation issues in the past it is essential to inform your treating doctor or oncologist. This is also a trap for patients being treated overseas where their complete medical history is not made available or where there are language and translation issues.
Formation of vascular blood clots is also a leading cause of death in cancer patients because cancer cells create conditions that favour clotting. We know that patients diagnosed with pancreatic, lung cancer, multiple myeloma, or hematologic malignancies are more likely to develop blood clots than other cancer patients due to cancer-specific factors, including their treatment regimens. These patients should receive particular attention in terms of preventative anti-coagulation therapy to decrease risk of events that could be fatal.
Dr Connors states that 10 percent of people diagnosed with DVT who do not have a known cancer will be diagnosed with cancer as part of the clot evaluation or in the next year to two years! PREVENTION AND AWARENESS:
Having seen so many patients with blood coagulation, DVT and embolisms; it serves as a warning sign that blood should be checked for coagulation problems as a part of wellness and disease prevention program. Did you know that egardless of cancer, if you are over 50; the greatest threat to your continued existence is the formation of abnormal blood clots in your arteries and veins. Even athletes and those who are physically fit can be at high risk.
Dietary management and adjustments can help reduce risk – as well as some plant-based phyto-chemicals that have been proven to decrease blood viscosity. However – self diagnosing blood coagulation problems and taking supplements for “blood-thinning” or even taking excessive amounts of foods known to help “thin the blood” is not recommended.
Recently I had a patient who experienced massive bleeding during a biopsy procedure. Her surgeon had told her to avoid aspirin and fish oil for 5 days before her procedure – which she dutifully did. However she was juicing large amounts of fresh ginger daily as well as turmeric root and she was making a juice from cabbage, mustard greens and turnip greens broccoli, asparagus an apple.
She almost bled out on the operating table and has had a long recovery due to excessive blood loss. It is not hard to see why specialists say to cancer patients when asked if they can have certain foods and supplements – “TAKE NOTHING – AVOID SUPPLEMENTS AND DON’T CHANGE YOUR DIET TOO MUCH”.
When the famous Hippocrates said “Let your food be your medicine and your medicine be your food” he did not mean juicing a wheelbarrow load of fruit and veges every day!!!
It is useful to know that several herbal preparations ( natural and supplemental) interfere with the anti-clotting activity of blood thinners and can increase bleeding time or your risk of bleeding. Garlic, ginger, celery seed, ginseng, curcumin and aniseed all carry coumarin effects (meaning that they can prevent your blood from clotting…. the opposite coagulation focussed on in this article.). (NOTE: Avoid combining tumeric (active ingredient curcumin) with anticoagulant and/or antiplatelet drugs. If you take blood thinning medication
Due to “blood thinning” side effects of turmeric; cease to take it at least two weeks before any surgical procedure.
Two other helpful suggestions about taking Tumeric ( cucumin)
Caution with Diabetes. Turmeric may lower blood sugar. Avoid turmeric if you take diabetes medications, since turmeric could cause your blood sugar to fall even further. This could result in hypoglycemia.
Caution with Gallbladder. The NIH recommends avoiding turmeric if you currently have problems with your gallbladder. If you have gallstones or a bile duct obstruction, turmeric may cause your condition to worsen.
Foods rich in vitamin E are also natural blood thinners.
Botanical Science and nutritional science knowledge tend to be little adhered to by the current fad that more is better whether in juice, smoothie or supplement. People are flocking to buy machines that will pulverise 10 carrots and 4 blocks of tofu along with bunches of kale and spinach etc in the pursuit of “health and wellbeing”!
In fact these approaches can really have a negative impact of health and wellbeing which I am already seeing in my Practice.
Case managing patients who wish to use complementary medicines and nutritional approaches alongside conventional medicine – presents a challenging management situation to health practitioners.
In our practice I do my best alongside my colleague Dr Whelan to gain patient’s trust in advising on what to take as supplements and foods. With 87 years experience between us – we try to educate and advise simplicity as a targeted approach – rather than trying to “hit a mosquito with a shotgun” – the one size fits all approach. We know they will be tempted and influenced by fellow patients and incorrect information in books and approaches generated by faddist cancer entrepreneurs as well as Dr Google. Experience tells us that our educated patients do very well indeed.
As another example of the importance of botanical science knowledge and how a simple food might heal or hinder. While research suggests that tangeretin in mandarin oranges may help prevent cancer, people who already have cancer may not reap any benefits. In fact, a diet rich in mandarin oranges may provide counteractive results in these people as tangeretin appears to interfere with metabolism of some drugs, including the anti-cancer drug tamoxifen. Mandarins and grapefruit are just two of many foods that should be avoided due to interactions with life-saving pharmaceutical treatments.
ASK A HEALTH PROFESSIONAL WHO IS QUALIFIED AND EXPERIENCED IN CANCER AND HERB/NUTRITIONAL DRUG INTERACTIONS TO DESIGN A PERSONALIZED HEALTH RESTORATION PROGRAM FOR YOU.
Realise that your situation will change as response and treatments change. This is why regular communication and case management is imperative for every cancer patient.
For those cancer patients who live in Queensland – you might like to visit our Gold Coast based consulting rooms where Blood tests and other checks can be organised to increase your wellbeing and lower risks of blood disorders and assist with your cancer management program. More information? Email me via the contact page on this blog or visit www.gracegawlerinstitute.com or www.drwhelan.com
Recommendation – Ongoing Management:
If you are diagnosed with a blood clot, be sure to complete all age-appropriate cancer screenings, including mammograms, Pap smears, and colonoscopies, among others, to evaluate your cancer risk. If all tests are negative, implying no cancer is detected, then it has been recommended that the basic clinical evaluation is repeated every 6 months in the 2 years after the clot occurred. In this way, it is likely that most cancers, if they occur, will be promptly detected. If you know someone who has had DVT without a known cause – please direct them to the following video. We all know that early detection of cancer means better outcomes.
Today on Navigating the Cancer Maze I speak with Prof Brendon Coventry about melanoma and in particular, vaccines against melanoma. But more than a melanoma treatment, Cancer Vaccines are showing up as not only as a part of innovative and integrated oncology approaches; but as likely treatments for other types of cancers that have failed conventional treatments such as radiation and chemotherapy protocols.
Today on Navigating the Cancer Maze I speak with Prof Brendon Coventry about melanoma and in particular, vaccines against melanoma. But more than a only a melanoma treatment, Cancer Vaccines are showing up as not only as a part of innovative and integrated oncology approaches; but as likely treatments for other types of cancers that have failed conventional treatments such as radiation and chemotherapy protocols. For example Jeffrey Deslandes,who after 4 recurrences of NH lymphoma – found his success with cancer vaccines. He is 9 years clear of the disease.
The combination of Surgical Oncologist in combination with a PhD in Immunology – is rare; but this is what Prof Coventry brings to the cancer “treatment table”. He has many years experience in cancer research, vaccine therapies and the role of the immune system in cancer control.
To Listen to audio of show – 4 sessions – select each link below
Listen to Navigating the Cancer Maze-with Prof Brendon Coventry
Sessions oneto four with
Remember the show is for you and sponsored by our charity – The Grace Gawler Institute. It is free to air and free to listen live streaming within an hour of live broadcast. It is archived indefinitely on my Voice America Page. Crucial to the shows intention – to educate patients and families about the availability of scientifically valid cancer treatments and safe and effective complementary medicine; we ask that you forward the ecard (available on the website) or URL to those you know who are trying to navigate the increasingly complex cancer maze.
Every week, some 160,000 people die of advanced cancer around the world, despite our best attempts at cancer treatment globally. Some $32 billion is being spent on oncology drugs and the USA National Cancer Institute/ NIH spends about $5.2 billion on cancer research, per annum. Sadly, cancer has remained a tremendously costly public health problem of major proportions for over 5 decades, and our progress has been puzzling slow towards solving this using standard methods.
On today’s show, Navigating the Cancer Maze, my guest Professor Brendon Coventry, an Adelaide-based oncology surgeon suggests there may be another way to approach the problem and shows that the immune system my hold the answer. With a special interest in Melanoma Surgery, he is a clinical researcher whose interests include anti-tumour immune response in human malignancies, tumour Immunology and cancer vaccine treatments.
His group’s research paper, published in 2014, entitled “Vaccinia Melanoma Cell Lysate Vaccine (VMCL) Trial for treatment of advanced Stage IV Melanoma with and without Chemotherapy”, captured the attention of medical and scientific community. Trial conclusions reported high complete response rates (where all cancer disappears) of 17%, with useful clinical responses occurring in nearly 80% of patients overall (slowing the disease), and over 15% of patients experiencing survivals past 5-years, with essentially no toxicity. The longest survivor now remains alive for over 14 years. These response rates and survivals are unusual for advanced melanoma. The researchers reason that the repetitive and prolonged delivery of the vaccine therapy might hold part of the clue, because this was a strikingly different approach to that used in other trials.
Prof Coventry with colleague Martin Ashdown, have now developed a remarkable understanding of how the human immune system continuously oscillates in a dynamic fashion. The timing of ‘when’ the therapy dose is precisely delivered in synchrony with each individual patient’s own immune system waveform or cycle might hold the very key to improving cancer treatment, thus leading to better survival.
Martin Ashdown says: …..”The concept of immune monitoring and accurately synchronizing therapy (immune synchronization), brings a new level of science to oncology. The published mouse experiments and human clinical trials, together with our knowledge of physiology tells us this is the way forward, particularly with the new cancer immunotherapies. This approach potentially has the triple benefit of increasing efficacy, lowering toxicity and substantially reducing the cost of treatment”
Professor Brendon Coventry is well crendentialled
Professor Brendon Coventry BMBS, PhD, FRACS, FACS, FRSM is an Associate Professor of Surgery at the University of Adelaide and Senior Consultant Surgeon (General, Breast-Endocrine, Surgical Oncology & Trauma Surgery) at the Royal Adelaide Hospital since 1993.
He holds a PhD in cancer immunology.
Positions:
• Immediate Past Chairman, Surgical Oncology Section, Royal Australasian College of Surgeons;
• Research Director, Australian Melanoma Research Foundation & Board Member;
• Past Chairman, Melanoma and Skin Cancer Group, Clinical Oncological Society of Australia;
• Foundation Chairman, Multidisciplinary Melanoma Management Group, Royal Adelaide Hospital
• Senior Examiner, Australian Medical Council
• Board Member of Cancer Care Centre, Unley
Fellowships:
• Royal Australasian College of Surgeons,
• American College of Surgeons
• Royal Society of Medicine.
Research:
• Over 85 journal publications; including New England Journal of Medicine, British Journal of Cancer, Journal of Clinical Oncology, Lancet Oncology; widely published topics including surgical treatment for melanoma and breast cancer, sentinel node surgery, sarcoma surgery, adjuvant radiation therapy, melanoma vaccine therapies,laparoscopic spleen surgery techniques, neuroscience, microscopic methods, high-sensitivity tissue immunochemistry, public health,
medical education, internet learning.
• NIH Principal Investigator: Multicenter Selective Lymphadenectomy Trial (MSLT-I) surgical sentinel node; C-Vax melanoma vaccine studies (x2).
• Editor-in-Chief, 7-Volume international textbook series “Surgery: Complications, Risks and Consequences” published by Springer; general adult, paediatric and cardio-vascular surgery. Current Research:
• Surgical Complications, Safety and Quality improvement
• Vaccine Therapies for Advanced Melanoma, novel findings from repetitive dosing where 5-year survival and Complete Response rates have been significantly improved
• Timing of Therapies is novel collaborative work with Martin Ashdown concerning serial blood biomarker monitoring for advanced cancer patients for more accurate timing to improve therapy dose delivery and clinical efficacy further, which is gaining recognition
More on Vaccine successes – listen to Jeffrey Deslandes interviewed on Juice radio – Gold Coast yesterday 16 January 2015. https://soundcloud.com/juice-107-3/cancer-survivor-jeffrey-deslandes
Sometimes we can’t make financial donations for a cause – but we can use the internet, emails social media and word of mouth to help bring about change. Patient demand through critical need will make a difference- but voices are required! Please spread the wordabout this interview and the show and make your contribution to change the paradigm of treating cancer for the benefit of humanity.
On this week’s Navigating the Cancer Maze on Voice America radio, I presented an encore broadcast of a special interview with my colleague GP Dr Bruce Whelan: “Spinning Gold from Straw: How trauma transformed a Doctor’s Life and Practice”. This year, Dr Whelan and I have forged a very special medical partnership to help patients Navigate the Cancer Maze – Health Intelligence Australia.
On this week’s Navigating the Cancer Maze on Voice America radio, I presented an encore broadcast of a special interview with my colleague GP Dr Bruce Whelan: “Spinning Gold from Straw: How trauma transformed a Doctor’s Life and Practice”. This year, Dr Whelan and I have forged a very special medical partnership to help patients Navigate the Cancer Maze – Health Intelligence Australia.
Last week a patient asked me what makes Dr. Bruce Whelan unique in terms of the type of medicine he practises? The answer came easily. In the past 10 years Bruce has become involved with and specialized in management of addictions, mental health and severe and chronic pain as well as general medicine. These are also all important aspects of cancer management. They are the areas of medicine that tend to be under-serviced by GPs due to time constraints or lack of training. But there is more that makes Dr Bruce Whelan uniquely suited to the new Health Intelligence Australiagroup.
Another area of Dr Bruce Whelan’s expertise is in the area of trauma. He knows a lot about trauma at a very personal level because in 2002 he was summoned to Bali from Sri Lanka, where he was working. He was given the unspeakably grim task of identifying bodies after the bombing at the Sari Club in Bali. His task was made even worse when he spent two days unsuccessfully trying to find and identify the body of his son-in-law Shane – killed in the bombing along with a partner of his daughter’s friend. As luck had it the girls were going to be late getting to the Sari Club that night. But lucky as they were to escape; the trauma of the incident lived on and shaped their future.
When Bruce graduated from the University of Queensland in 1967, like many of us, he had no idea what life had in store for him. As a doctor, Bruce Whelan had already seen lot of suffering, but the post-traumatic stress affect that the Bali incident produced, had long lasting effects. The product of uninvited change! Bruce fought a battle he could not win; to have bodies quickly identified, stored appropriately and repatriated to Australia.
This intensified the trauma, grief and loss experienced by many. However, being a resourceful doctor, eventually he was able to spin gold from straw as they say, and today, 14 years later; the experience brings with it a man who is the wounded healer who serves his patients with a rare quality of directness and authenticity. He is someone who deeply understands trauma and depression in another human being.
There is no substitute for this type of life experience. This type of experience can’t be learned in any university except in the university of life!
It is recognized by psycho-oncologists that a diagnosis of cancer is also a traumatic event and many patients experience PTSD (post traumatic stress disorder) that often remains undiagnosed and untreated throughout the course of the illness. Some patients have experienced trauma before diagnosis and it may not have been dealt with. Unrecognized trauma can play a complicated role in the ongoing management of illness. Major life traumas can impact every treatment approach that a cancer patient will try during their recovery….. it can even affect patients who are survivors of the physical illness, but who did not have the opportunity to deal with the psychological impact of the illness at the time. This often plays out as depression, memory loss or dissociative disorders.
To make an appointment for a consultation to see either myself or Dr Whelan, or for a team consultation, please visit: