Options, Choices and Treatments for Cancer Recovery| Navigating the Cancer Maze

New cancer treatments are always controversial; BUT – this method is not a treatment. It’s a smart approach. A Smart approach that utilizes all that we know so far about cancer. It works because ultimately; our innate immune system knows what to do.

Options, Choices and Treatments for Cancer Recovery: De mystifying the oscillating the immune cycle.

When my ex husband and I had the idea for starting support groups for cancer patients in the early 1980’s. cancer organizations, patients and doctors were initially not supportive. In fact they were skeptical. They could not see any possible therapeutic benefit could come from people attending a support group.  How wrong they were! Move forward Body rhythms diagram40 years! Yes this December marks my beginning working with cancer patients 40 years ago in a time when there was no support in the health system and no support groups. Now, the benefit of patients attending structured supports and the well being benefit is indisputable.

There are still many new areas to explore, which leads me to discussing the immune cycle. It would seem that during 2014 on Navigating the Cancer Maze – we uncovered and delivered some significant “missing” pieces of the cancer treatment puzzle. It is my hope that as 2014 comes to an end – that 2015 will truly usher in a new paradigm in cancer treatments. The foundation has been laid, extensive research already done, the concept has been introduced worldwide – the  immune cycle measurement is here – NOW!
Now it is up to cancer patients to prove Martin Ashdown and Brendon Coventry right….or wrong. I liked it when Martin Ashdown said – “We believe this is so, a breakthrough – but we are open to being proven wrong!” As in the early days of my first charitable  foundation – it was people power – patient power that made a difference to the success of the Cancer Support Group Movement. Once told there would likely be a measured benefit from attending a support group – the press broadcast the news and the patients came on board en masse!

New cancer treatments are always controversial; BUT – this method is not a treatment. It’s a smart approach. A Smart approach that utilizes all that we know so far about cancer. It works because ultimately; our innate immune system knows what to do. It is just in temporary overwhelm. So doesn’t it make perfect sense that to find the best time to work in synch within the cycle of each person’s immune system to add the best chemotherapy or monoclonal antibody or other targeted treatment. Isn’t this the personalized approach we have been searching for? We all thought it would come in a pill – not an approach and that’s a paradigm shift that some in the world of science and medicine are struggling with.

measuring immune cycleKnowing how one’s immune cycle oscillates holds a clue, “the missing link” that can direct doctors to seek the best time to treat patients in their personal window of opportunity. Then within the parameters of what we know they will have the best chance of a good response or complete response to treatment. (CR)

When cancer cells challenge us – they are also smart. They are a part of us created by our internal systems. You could define cancer as an internal systems error!  These cancer cells cleverly recruit our intelligent mechanisms using them for their own growth and survival. It seems a bit crazy that something that wants to survive – kills its host. But – that’s life! To listen to the latest Voice America related to this blog visit:
http://www.voiceamerica.com/episode/82056/options-choices-and-treatments-for-cancer-recovery

So – I believe as do Ashdown and Coventry – that if there is enough of the immune response left in a patient – that the cycle can still be measured and timed so administer the right treatment at the right time. It is simple enough – the only real cost being a series of blood tests. Then finding a doctor who will look at the science and research and say yes – they administer treatment during the 12 hour window of opportunity. The Grace Gawler Institute is keen to let you know and experience the immune cycle for yourself. Please Read more below or join the immune cycle registry at:

http://www.gracegawlerinstitute.com/immune-cycle-registry/ also see our Next “Survivor Academy” Course!

Martin Ashdown and Brendon Coventry have built upon earlier excellent work in the study of chronobiology: Below are references given on Navigating the Cancer Maze today: I have provided abstract content as well as links.

Until next time……Grace

  • Annu Rev Pharmacol Toxicol. 2010;50:377-421. doi: 10.1146/annurev.pharmtox.48.113006.094626.
    Circadian timing in cancer treatments.
    Lévi F1, Okyar A, Dulong S, Innominato PF, Clairambault J.
    Author information
    Abstract
    The circadian timing system is composed of molecular clocks, which drive 24-h changes in xenobiotic metabolism and detoxification, cell cycle events, DNA repair, apoptosis, and angiogenesis. The cellular circadian clocks are coordinated by endogenous physiological rhythms, so that they tick in synchrony in the host tissues that can be damaged by anticancer agents. As a result, circadian timing can modify 2- to 10-fold the tolerability of anticancer medications in experimental models and in cancer patients. Improved efficacy is also seen when drugs are given near their respective times of best tolerability, due to (a) inherently poor circadian entrainment of tumors and (b) persistent circadian entrainment of healthy tissues. Conversely, host clocks are disrupted whenever anticancer drugs are administered at their most toxic time. On the other hand, circadian disruption accelerates experimental and clinical cancer processes. Gender, circadian physiology, clock genes, and cell cycle critically affect outcome on cancer chronotherapeutics. Mathematical and systems biology approaches currently develop and integrate theoretical, experimental, and technological tools in order to further optimize and personalize the circadian administration of cancer treatments.
    PMID:
    20055686
    [PubMed – indexed for MEDLINE]
  • http://www.ncbi.nlm.nih.gov/pubmed/20055686

Ann Pharm Fr. 2008 Jun;66(3):175-84. doi: 10.1016/j.pharma.2008.05.003.
[The circadian-timing system: a determinant of drug activity and a target of anticancer treatments].
[Article in French]
Lévi F.
Author information
Abstract
Cellular proliferation and drug detoxification are controlled over the 24h by the circadian-timing system, whose disruption can favor malignant processes. Thus, prolonged shift work appears to increase the risk of breast, colon or prostate cancer. Alterations in circadian physiology and/or molecular-clock genes accelerate cancer progression in experimental models and in cancer patients. In addition, anticancer treatments can also dampen or reinforce the circadian-timing system, as a function of dose and time of administration. The adjustment of anticancer-drug delivery to the circadian-timing system (chronotherapeutics) has allowed to reduce five-fold the incidence of severe adverse events as compared to constant rate infusion or wrongly-timed chronomodulated delivery in cancer patients. In experimental models, the best antitumor efficacy is usually obtained following treatment delivery near the least toxic time, a statement that also seems to apply to patients. Dedicated technologies include programmable in time pumps and rhythm monitors and are required for chronotherapeutics. Recent results have revealed that the optimal chronotherapeutic schedule could differ as a function of gender and circadian physiology. In conclusion, the circadian-timing system was shown to negatively control malignant proliferation via partly identified molecular mechanisms. The components of the circadian-timing system thus constitute new potential therapeutic targets in oncology. Mathematical models help toward a better understanding of the role of variability for the determination of the optimal chronotherapeutic schedule and constitute useful tools for the personalization of cancer chronotherapeutics.

http://www.ncbi.nlm.nih.gov/pubmed/18706346

Handb Exp Pharmacol. 2013;(217):261-88. doi: 10.1007/978-3-642-25950-0_11.
Cancer chronotherapeutics: experimental, theoretical, and clinical aspects.
Ortiz-Tudela E1, Mteyrek A, Ballesta A, Innominato PF, Lévi F.
Author information
Abstract
The circadian timing system controls cell cycle, apoptosis, drug bioactivation, and transport and detoxification mechanisms in healthy tissues. As a consequence, the tolerability of cancer chemotherapy varies up to several folds as a function of circadian timing of drug administration in experimental models. Best antitumor efficacy of single-agent or combination chemotherapy usually corresponds to the delivery of anticancer drugs near their respective times of best tolerability. Mathematical models reveal that such coincidence between chronotolerance and chronoefficacy is best explained by differences in the circadian and cell cycle dynamics of host and cancer cells, especially with regard circadian entrainment and cell cycle variability. In the clinic, a large improvement in tolerability was shown in international randomized trials where cancer patients received the same sinusoidal chronotherapy schedule over 24h as compared to constant-rate infusion or wrongly timed chronotherapy. However, sex, genetic background, and lifestyle were found to influence optimal chronotherapy scheduling. These findings support systems biology approaches to cancer chronotherapeutics. They involve the systematic experimental mapping and modeling of chronopharmacology pathways in synchronized cell cultures and their adjustment to mouse models of both sexes and distinct genetic background, as recently shown for irinotecan. Model-based personalized circadian drug delivery aims at jointly improving tolerability and efficacy of anticancer drugs based on the circadian timing system of individual patients, using dedicated circadian biomarker and drug delivery technologies.
http://www.ncbi.nlm.nih.gov/pubmed/23604483

Chronobiol Int. 2002 Jan;19(1):1-19.
From circadian rhythms to cancer chronotherapeutics.
Lévi F.
Author information
Abstract
Mammalian circadian rhythms result from a complex organization involving molecular clocks within nearly all “normal” cells and a dedicated neuroanatomical system, which coordinates the so-called “peripheral oscillators.” The core of the central clock system is constituted by the suprachiasmatic nuclei that are located on the floor of the hypothalamus. Our understanding of the mechanisms of circadian rhythm generation and coordination processes has grown rapidly over the past few years. In parallel, we have learnt how to use the predictable changes in cellular metabolism or proliferation along the 24h time scale in order to improve treatment outcome for a variety of diseases, including cancer. The chronotherapeutics of malignant diseases has emerged as a result of a consistent development ranging from experimental, clinical, and technological prerequisites to multicenter clinical trials of chronomodulated delivery schedules. Indeed large dosing-time dependencies characterize the tolerability of anticancer agents in mice or rats, a better efficacy usually results from treatment administration near the least toxic circadian time in rodent tumor models. Programmable in time multichannel pumps have allowed to test the chronotherapy concepts in cancer patients and to implement chronomodulated delivery schedules in current practice. Clinical phase I and II trials have established the feasibility, the safety, and the activity of the chronotherapy schedules, so that this treatment method has undergone further evaluation in international multicenter phase III trials. Overall, more than 2,000 patients with metastatic disease have been registered in chronotherapy trials. Improved tolerability and/or better antitumor activity have been demonstrated in randomized multicenter studies involving large patient cohorts. The relation between circadian rhythmicity and quality of life and even survival has also been a puzzling finding over the recent years. An essential step toward further developments of circadian-timed therapy has been the recent constitution of a Chronotherapy cooperative group within the European Organization for Research and Treatment of Cancer. This group now involves over 40 institutions in 12 countries. It is conducting currently six trials and preparing four new studies. The 19 contributions in this special issue reflect the current status and perspectives of the several components of cancer chronotherapeutics.
PMID:
11962669
[PubMed – indexed for MEDLINE]

http://www.ncbi.nlm.nih.gov/pubmed/11962669
Cancer Causes Control. 2006 May;17(4):611-21.
Chronotherapeutics: the relevance of timing in cancer therapy.
Lévi F.
Author information
Abstract
BACKGROUND:
Cell physiology is regulated along the 24-h time scale by a circadian timing system composed of molecular clocks within each cell and a central coordination system in the brain. The mammalian molecular clock is made of interconnected molecular loops involving at least 12 circadian genes. The cellular clocks are coordinated by the suprachiasmatic nuclei, a hypothalamic pacemaker which also helps the organism adjust to environmental cycles. The rest-activity rhythm is a reliable marker of the circadian system function in both rodents and man. This circadian organization is responsible for predictable changes in the tolerability and efficacy of anticancer agents, and possibly also in tumor promotion or growth.
METHODS:
Expected least toxic times of chemotherapy were extrapolated from experimental models to human subjects with reference to the rest-activity cycle. The clinical relevance of the chronotherapy principle, i.e. treatment administration as a function of rhythms, has been demonstrated in randomized multicenter trials.
RESULTS:
Chronotherapeutic schedules have been used to safely document the activity of the association of oxaliplatin, 5-FU and leucovorin against metastatic colorectal cancer and to set up a new medicosurgical management of this disease which achieved unprecedented long term survival.
CONCLUSION:
The chronotherapy concept offers further promises for improving current cancer treatment options as well as for optimizing the development of new anticancer or supportive agents.
PMID:
16596317
[PubMed – indexed for MEDLINE]

Mol Med. 2012 Dec 6;18:1249-60. doi: 10.2119/molmed.2012.00077.
Circadian rhythm disruption in cancer biology.
Savvidis C1, Koutsilieris M.
Author information
Abstract
Circadian rhythms show universally a 24-h oscillation pattern in metabolic, physiological and behavioral functions of almost all species. This pattern is due to a fundamental adaptation to the rotation of Earth around its own axis. Molecular mechanisms of generation of circadian rhythms organize a biochemical network in suprachiasmatic nucleus and peripheral tissues, building cell autonomous clock pacemakers. Rhythmicity is observed in transcriptional expression of a wide range of clock-controlled genes that regulate a variety of normal cell functions, such as cell division and proliferation. Desynchrony of this rhythmicity seems to be implicated in several pathologic conditions, including tumorigenesis and progression of cancer. In 2007, the International Agency for Research on Cancer (IARC) categorized “shiftwork that involves circadian disruption [as] probably carcinogenic to humans” (Group 2A in the IARC classification system of carcinogenic potency of an agent) (Painting, Firefighting, and Shiftwork; IARC; 2007). This review discusses the potential relation between disruptions of normal circadian rhythms with genetic driving machinery of cancer. Elucidation of the role of clockwork disruption, such as exposure to light at night and sleep disruption, in cancer biology could be important in developing new targeted anticancer therapies, optimizing individualized chronotherapy and modifying lighting environment in workplaces or homes.
PMID:
22811066
[PubMed – indexed for MEDLINE]
PMCID:
PMC3521792
Free PMC Article

Chronobiol Int. 2012 Apr;29(3):227-51. doi: 10.3109/07420528.2012.658127.
Clock genes and clock-controlled genes in the regulation of metabolic rhythms.
Mazzoccoli G1, Pazienza V, Vinciguerra M.
Author information
Abstract
Daily rotation of the Earth on its axis and yearly revolution around the Sun impose to living organisms adaptation to nyctohemeral and seasonal periodicity. Terrestrial life forms have developed endogenous molecular circadian clocks to synchronize their behavioral, biological, and metabolic rhythms to environmental cues, with the aim to perform at their best over a 24-h span. The coordinated circadian regulation of sleep/wake, rest/activity, fasting/feeding, and catabolic/anabolic cycles is crucial for optimal health. Circadian rhythms in gene expression synchronize biochemical processes and metabolic fluxes with the external environment, allowing the organism to function effectively in response to predictable physiological challenges. In mammals, this daily timekeeping is driven by the biological clocks of the circadian timing system, composed of master molecular oscillators within the suprachiasmatic nuclei of the hypothalamus, pacing self-sustained and cell-autonomous molecular oscillators in peripheral tissues through neural and humoral signals. Nutritional status is sensed by nuclear receptors and coreceptors, transcriptional regulatory proteins, and protein kinases, which synchronize metabolic gene expression and epigenetic modification, as well as energy production and expenditure, with behavioral and light-dark alternance. Physiological rhythmicity characterizes these biological processes and body functions, and multiple rhythms coexist presenting different phases, which may determine different ways of coordination among the circadian patterns, at both the cellular and whole-body levels. A complete loss of rhythmicity or a change of phase may alter the physiological array of rhythms, with the onset of chronodisruption or internal desynchronization, leading to metabolic derangement and disease, i.e., chronopathology.
PMID:
22390237
[PubMed – indexed for MEDLINE]

An Answer to Cancer – How Your Immune Body-Clock can assist Complete Remission | Navigating the Cancer Maze

Cancer affects everyone around the world in some way. Friends, relatives, children, mums and dads, grans and grandpas! It does not discriminate. It causes as much or perhaps even more misery than war because it reaches into every race, culture and country! If there was just one thing we could add to the recipe for Curing cancer or extending life with quality and well-being – wouldn’t we all be excited and interested?Do you want to know one important missing piece of the cancer puzzle? Two cancer researchers Martin Ashdown & Brendon Coventry have explored that question and yes they are excited!

How Your Immune Body-Clock can assist Complete Remission: (Please pass on the link to this blog to those in need)

Cancer affects everyone around the world in some way. Friends, relatives, children, mums and dads, grans and grandpas! It does not discriminate. It causes as much or perhaps even more misery than war because it reaches into every race, culture and country!  If there was just one thing we could add to the recipe for Curing cancer or extending life with quality and well-being – wouldn’t we all be excited and interested? Do you want to know one important missing piece of the cancer puzzle?  Listen to today’s show at: http://www.voiceamerica.com/episode/81479/an-answer-to-cancer-how-your-immune-body-clock-can-assist-complete-remission

Measuring immune cycles
Measuring immune cycles may be one missing piece of the cancer cure puzzle!

The show is free to air on the internet – live streaming listening at any time- free download – archived indefinitely.

Two cancer researchers Martin Ashdown & Brendon Coventry have explored that question and yes they are excited! So am I and so are some doctors and oncologists! Testing patients to map their immune cycle is not a complex exercise, but to do this, a system needs to be changed. All discoveries of worth seem to be hobbled for while – then accepted – struggling across the finish line…sometime after decades!

In 1983, Australian doctors J. Robin Warren and Barry Marshall isolated Helicobacter pylori, the bacterial cause of peptic ulcer disease. When the H. pylori hypothesis was developed, the doctors were certain that it would immediately gain universal acceptance and that within two years peptic ulcer therapy would be essentially an antimicrobial regimen”. This was far from the case. A 1986 book on Peptic Ulcer and its Drug Causation lends a page to the bacterial hypothesis, noting, “Whether these bacteria have an aetiological role in peptic ulcer gastritis is unknown”. At this time, doctors still prescribed drugs to reduce stomach acidity and monitored patients for complications. The story of Helicobacter pylori’s acceptance as a pathogenic agent reveals the issues with the acceptance of new thought even when there is validation and justification. http://www.jyi.org/issue/delayed-gratification-why-it-took-everybody-so-long-to-acknowledge-that-bacteria-cause-ulcers/

There are ethical laws in place; essential for the safety of humans in medicine. Changed laws of medical ethics, prevent a modern reprise of Pasteur’s heroic demonstration of his rabies vaccine through the vaccination of an infected boy. Measuring each cancer patients immune cycle and timing their treatment at the right time –  is nothing akin to that! It simply makes sense!

Perhaps one can understand the caution in prescribing an antibiotic. Measuring immune cycles and timing treatment for a better outcome? Now to my way of thinking this fulfills the old Hippocratic oath – “Above all, do no harm!”

The Grace Gawler Institute has a history of wanting to procure the best treatment options for cancer patients. We feel that by educating patients about their immune cycle and taking this material to their doctor – they can help change the face of cancer treatment in a risk free experiment to prove (or not) the research work of Martin Ashdown & Brendon Coventry.  This is why we have created the Cancer Immune Registry:

world cancer
Cancer affects everyone around the globe- it does not discriminate!

Background –  A cancer drug used for more than 20 years that is now providing oncologists with new information about how to best help patients achieve complete remission. The drug called interleukin-2, is providing cancer researchers with something akin to how the “Rosetta Stone” was used to unlock historical script; the outcome; mapping the immune cycle!

To understand how this is possible – join me with guest Martin Ashdown on Navigating the Cancer Maze on Voice America’s Health and Wellness channel ( internet radio)  to hear the full story of this amazing breakthrough.

Learn how you can access info about your immune cycle to assist cancer treatment efficacy.

RESOURCES:

1. http://www.voiceamerica.com/episode/81479/an-answer-to-cancer-how-your-immune-body-clock-can-assist-complete-remission

2. http://www.gracegawlerinstitute.com/immune-cycle-registry/

3. Martin Ashdown Window of Opportunity1 article: Australasian Science

4. MARTIN ASHDOWN A Matter of Time_AS_Article: article Australasian Science

5. VIDEO: Treatment of Metastatic Melanoma: Could Timing Be Everything? http://www.youtube.com/watch?v=yXX-9t8xiAo

6. CLICK  HERE FOR PRESS RELEASE VOICE AMERICA

7. CLICK HERE FOR VOICEAMERICA PRESS PASS RELEASE

An Answer to Cancer – How Your Immune Body-Clock can assist Complete Remission Grace Gawler with Martin Ashdown

Could timing of cancer treatments be the missing link in delivery of cancer therapies? Sounds too simple to be true? Two cancer researchers Martin Ashdown & Brendon Coventry are “immunological explorers” who not only unearthed a buried “treasure”; but they have also created a map for other innovative cancer “explorers” to follow. The “treasure” is a cancer drug used for more than 20 years that is now providing oncologists with new information about how to best help patients achieve complete remission. The drug called interleukin-2, is providing cancer researchers with something akin to how the “Rosetta Stone” was used to unlock historical script; the outcome; mapping the immune cycle!

An Answer to Cancer – How Your Immune Body-Clock can assist Complete Remission

Be sure to mark this coming weekend in your diary (7,8 November) to listen to this inspiring and significant edition of Navigating the Cancer Maze.

The Cancer Immune Cycle - A Window of Opportunity in Treatment Efficacy
The Cancer Immune Cycle – A Window of Opportunity in Treatment Efficacy

The show can be downloaded on itunes or reached at any time live streaming at the link below.
http://www.voiceamerica.com/episode/81479/an-answer-to-cancer-how-your-immune-body-clock-can-assist-complete-remission

The show is broadcast by Voice America on internet radio – but is distributed world wide and is a must for all cancer patients. Please select link at bottom of page to be directed to the eCard for this weeks edition. You can also sign up with Voice America to receive notice of ongoing shows. You can also sign up and follow this blog ( in the right side bar)  to receive weekly invaluable cancer information and Navigating the Cancer Maze links direct to your email inbox.

We know you will be inspired and encouraged by this show – so we have a call to action page on our website where cancer patients can be involved.

To join or read about the Cancer Immune Cycle Registry
please visit: http://www.gracegawlerinstitute.com/immune-cycle-registry/

 

This week……..An Answer to Cancer – How Your Immune Body-Clock can assist Complete Remission

Could timing of cancer treatments be the missing link in delivery of cancer therapies? Sounds too simple to be true? Two cancer researchers Martin Ashdown & Brendon Coventry are “immunological explorers” who not only unearthed a buried “treasure”; but they have also created a map for other innovative cancer “explorers” to follow. The “treasure” is a cancer drug used for more than 20 years that is now providing oncologists with new information about how to best help patients achieve complete remission. The drug called interleukin-2, is providing cancer researchers with something akin to how the “Rosetta Stone” was used to unlock historical script; the outcome; mapping the immune cycle! Join me with guest Martin Ashdown on Navigating the Cancer Maze to hear the story of this amazing breakthrough. Learn how you can access info about your immune cycle to assist cancer treatment efficacy.            Please Remember to like us on Facebook!

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How Surgeons can Help you Navigate the Colorectal Cancer Maze | Dr Francis Seow Choen with Grace Gawler

Dr Francis Seow Choen is himself a medical miracle. As a 7 year old he recovered from major surgery for a cancer in his small intestine after facing a horrendous 6 months of radiation treatment and chemotherapy back in 1964 when treatments were harsh. He survived! Dr. Seow-Choen graduated from the National University of Singapore in 1981 & obtained his higher surgical qualifications in 1987. He sub-specialised in colorectal surgery in 1989 where he worked with the world-class surgeons of St Marks’ Hospital in London. He is a remarkable CR surgeon.

Part 2 – How Surgeons can Help you Navigate the Colorectal Cancer Maze

Dr Francis Seow Choen MBBS (Spore), FRCS (Edin), FAMS

Dr Francis Seow Choen Fortis Surgical Hospital Singapore
Dr Francis Seow Choen Fortis Surgical Hospital Singapore

Dr Francis Seow Choen is himself a medical miracle. As a 7 year old he recovered from major surgery for a cancer in his small intestine after facing a horrendous 6 months of radiation treatment and chemotherapy back in 1964 when treatments were harsh. He survived! Interview CLICK HERE

Dr. Seow-Choen graduated from the National University of Singapore in 1981 & obtained his higher surgical qualifications in 1987. He sub-specialised in colorectal surgery in 1989 where he worked with the world-class surgeons of St Marks’ Hospital in London. He is a remarkable CR surgeon.

I have interviewed Dr Francis Seow Choen previously on my internet radio show Navigating the Cancer Maze at Voice America. This time however, we touch on more details about the surgical techniques available for anyone dealing with colorectal cancer today.

As well, speaking as CR surgeon and recovered patient; he had a powerful message to cancer patients. Listen to this short excerpt from his interview: Select the icon below right to hear Dr Seow Choen’s message.

A personal message to cancer patients from Dr Francis Seow Choen
A personal message to cancer patients from Dr Francis Seow Choen

I have tremendous respect for the art and science of surgery. My own introduction to surgery came when I was 15 years of age. I began working in a veterinary clinic after school, then during holidays and for while as permanent staff. I was fortunate that the owner took me on as an apprentice as he knew my passion was to become a veterinarian. So, not only did I learn “hands-on” labrador retriever at the vetsurgery at an early age – I also was involved in co-performing post postmortems on animals which has served as a treasured learning field for understanding anatomy, physiology and pathology – many older dogs and cats who succumbed to an advanced and previously undiagnosed cancer that became a postmortem exercise; allowed me to see a wide range of cancers in vivo.

On the other hand, I was also impressed in how quickly animals responded to surgery for cancer and that for a high percentage of our animal clients – of those  caught early in diagnosis; few had a recurrence. There were also cases where enormous tumour loads were surgically removed, and the dog lived a long life afterwards! It was here that I developed a tremendous respect for surgical skills and the associated healing potential and regenerative powers that along with our animal friends, we all possess. However, surgery has come a long way since those days when robotic surgery entered the arena a few years ago.

You will find today’s interview with Dr Seow Choen informative, especially regarding the techniques using the new DaVinci Robotic surgery technology. You can read more about this technique as well as listening to the interview with Dr Seow Choen at: http://www.voiceamerica.com/episode/80875/how-surgeons-can-help-you-navigate-the-colorectal-cancer-maze-part-2

Singapore Fortis surgical Hospital da-Vinci-Robotic-Surgery equipment
Singapore Fortis surgical Hospital da-Vinci-Robotic-Surgery equipment

 

Dr. Seow-Choen helped establish the first colorectal surgery department in Asia at Singapore General Hospital (SGH) and is considered a leader in the development in CR surgery and approaches to treatment.

In this interview with Dr Seow Choen he also comments on diet and nutrition for cancer patients from the viewpoint of an experienced CR surgeon.

You may be surprised what he says……

 In the last segment of today’s show, I provide an overview on treatments available for CR cancer in 2014. A not to be missed show!

DaVinci robotic surgery technology
DaVinci robotic surgery technology

Resources:

Contact: www.fortissurgicalhospital.com to learn more…..

Or visit Dr Seow Choen’s website:

http://www.colorectalcentre.com/eng/index.html 

Don’t miss reading the informative medical media articles  at……….

http://www.colorectalcentre.com/eng/media_articles.html

If you missed last weeks interview with Dr Seow Choen’s colleague Dr Lim Jit Fong –

CLICK HERE TO LISTEN

Remember all interviews on Navigating the Cancer Maze are free to air (on live streaming and available from the archives anytime) and can be downloaded for free on itunes.

The show is not copyright and is available to distribute in the interest of cancer education and public awareness.

The show is available globally and is sponsored by donations to the Grace Gawler Institute a registered NFP Health Promotion Charity with DGR status based in Australia with a global outreach.

Introducing Health Intelligence Australia-A new Model of Healthcare Grace Gawler and Dr Bruce Whelan

On this week’s Navigating the Cancer Maze on Voice America radio, I presented an encore broadcast of a special interview with my colleague GP Dr Bruce Whelan: “Spinning Gold from Straw: How trauma transformed a Doctor’s Life and Practice”. This year, Dr Whelan and I have forged a very special medical partnership to help patients Navigate the Cancer Maze – Health Intelligence Australia.

On this week’s Navigating the Cancer Maze  on Voice America radio, I presented an encore broadcast of a special interview with my colleague GP Dr Bruce Whelan: “Spinning Gold from Straw: How trauma transformed a Doctor’s Life and Practice”. This year, Dr Whelan and I have forged a very special medical partnership to help patients Navigate the Cancer Maze – Health Intelligence Australia.
Last week a patient asked me what makes Dr. Bruce Whelan unique in terms of the type of medicine he practises? The answer came Health intelligence australiaeasily. In the past 10 years Bruce has become involved with and specialized in management of addictions, mental health and severe and chronic pain as well as general medicine. These are also all important aspects of cancer management. They are the areas of medicine that tend to be under-serviced by GPs due to time constraints or lack of training. But there is more that makes Dr Bruce Whelan uniquely suited to the new Health Intelligence Australia group.
Another area of Dr Bruce Whelan’s expertise is in the area of trauma. He knows a lot about trauma at a very personal level because in 2002 he was summoned to Bali from Sri Lanka, where he was working.  He was given the unspeakably grim task of identifying bodies after the bombing at the Sari Club in Bali. His task was made even worse when he spent two days unsuccessfully trying to find and identify the body of his son-in-law Shane – killed in the bombing along with a partner of his daughter’s friend. As luck had it the girls were going to be late getting to the Sari Club that night. But lucky as they were to escape; the trauma of the incident lived on and shaped their future.
When Bruce graduated  from the University of Queensland in 1967, like many of us, he had no idea what life had in store for him. As a doctor, Bruce Whelan had already seen lot of suffering, but the post-traumatic stress affect that the Bali incident produced, had long lasting effects. The product of uninvited change!  Bruce fought a battle he could not win; to have bodies quickly identified, stored appropriately and repatriated to Australia.

Dr Bruce Whelan
Dr Bruce Whelan

This intensified the trauma, grief and loss experienced by many. However, being a resourceful doctor, eventually he was able to spin gold from straw as they say, and today, 14 years later; the experience brings with it a man who is the wounded healer who serves his patients with a rare quality of directness and authenticity. He is someone who deeply understands trauma and depression in another human being.

There is no substitute for this type of life experience. This type of experience can’t be learned in any university except in the university of life!
It is recognized by psycho-oncologists that a diagnosis of cancer is also a traumatic event and many patients experience PTSD (post traumatic stress disorder) that often remains undiagnosed and untreated throughout the course of the illness. Some patients have experienced trauma before diagnosis and it may not have been dealt with. Unrecognized trauma can play a complicated role in the ongoing management of illness. Major life traumas can  impact every treatment approach that a cancer patient will try during their recovery….. it can even affect patients who are survivors of the physical illness, but who did not have the opportunity to deal with the psychological impact of the illness at the time.  This often plays out as depression, memory loss or dissociative disorders.
To make an appointment for a consultation to see either myself or Dr Whelan, or for a team consultation,  please visit:
RESOURCES:   Check out the following resources to understand more about PTSD and the brain:The Biology of Trauma           http://www.natal.org.il/english/?CategoryID=232
Article Psychology Today:   The Anatomy of Post traumatic Stress Disorder
Listen to interviews with Dr Bruce Whelan on Voice America – at http://www.drbrucewhelan.com/about-dr-bruce/

Navigating the Immune System | The Key to Future Cancer Therapies

Today on Voice America’s Navigating the Cancer Maze, I interview Professor Mark Smyth who is regarded as an international leader in tumour immunology, immunotherapy and natural killer (NK) cell biology. My co-host is Dr Bruce Whelan, GP.We are nk-cells-(green)-attack-diseased-human-cellsaware there is a great need for cancer education in the community. By understanding the intricacies of the immune system in parallel with the biological nature of cancer; we believe that patients will make better informed decisions regarding their choice of cancer treatment.

Prof Mark Smyth and Dr Bruce Whelan GP
Prof Mark Smyth and Dr Bruce Whelan GP

 

Today on Voice America’s Navigating the Cancer Maze, I interview Professor Mark Smyth who is regarded as an international leader in tumour immunology, immunotherapy and natural killer (NK) cell biology. My co-host is Dr Bruce Whelan, GP.

Episode Description

Today I interview Professor Mark Smyth who is regarded as an international leader in tumour immunology, immunotherapy and natural killer (NK) cell biology. My co-host is Dr Bruce Whelan, GP. Dr Whelan and I see cancer patients in our practices.

We are aware there is a great need for cancer education in the community. By understanding the intricacies of the immune system in parallel with the biological nature of cancer; we believe that patients will make better informed decisions regarding their choice of cancer treatmentProfessor Smyth is a person of influence who has made key discoveries in his field.

A number of those discoveries have led to new clinical trials in cancer immunotherapy. Professor Smyth relocated to the QIMR nk-cells-(green)-attack-diseased-human-cellsBerghofer in Brisbane (2013) as Senior Scientist and NH&MRC Australia Fellow.

He is a Senior Editor at Cancer Research, & a member of the Scientific Advisory Board of the Cancer Research Institute (USA).

Learn More:  www.qimrberghofer.edu.au

Professor Mark Smyth

Professor Mark Smyth  received his PhD from the University of Melbourne in 1988 & trained at the National Cancer Institute (USA) 1988-1992.

After 8 years at Austin Research Institute Melbourne, working on mechanisms of lymphocyte-mediated cytotoxicity, he relocated to Peter Macallum where his studies on effector molecules collectively rekindled world-wide interest in cancer immune surveillance. A number of his discoveries have led to new clinical trials in cancer immunotherapy.

Professor Smyth relocated to QIMR Berghofer, Brisbane (2013) as a Senior Scientist and NH&MRC Australia Fellow. He is a Senior Editor at Cancer Research, and a member of the Scientific Advisory Board of the Cancer Research Institute (USA).

Summary

The Immunology in Cancer and Infection Laboratory currently focuses upon advancing our understanding of the basic principles underlying an immune response to cancer and infection.

A Natural Killer cell (yellow) attacks a cancer cell. The NK cell reaches out and delivers the “kiss of death.”
A Natural Killer cell (yellow) attacks a cancer cell.
The NK cell reaches out and delivers the “kiss of death.”

 We aim to further understand these processes at the molecular level, with particular emphasis on the role of the innate immune system, in particular, NK cells, NKT cells and gamma-delta T cells.

Our laboratory is building a detailed picture of how networks of immune cells function to recognise, respond to, and destroy tumour cell masses and metastases. We are interested in defining the importance, timing, and nature of the natural immune response to transformation.

We are also using new antigens (including glycolipids), antibodies, and cytokines in combination to stimulate strong innate and lasting adaptive immunity to cancer.

Our findings are being used to develop more effective biological and cellular therapies for human cancer, in particular, melanoma, breast and prostate cancer, and haematological cancers.

Learn more about Prof Smyth’s research

at http://www.qimrberghofer.edu.au/page/Lab/Immunology_Cancer_Infection

 

One of QIMR Berghofer’s three Research Programs is cancer, one of the major causes of illness and death in Australia and the developed world.   In 2012, it is estimated that more than 120,700 Australians were diagnosed with cancer (excluding non-melanoma skin cancer). Cancer accounted for about 3 in 10 deaths in Australia, making it the second most common cause of death, exceeded only by cardiovascular diseases. Cancer is a disease which is caused by abnormal cell growth and eventually spreads to other parts of the body. Some cancers are common within a family history and are clearly inherited, while others are caused by factors in the environment interacting with genetic susceptibilities. Many forms of cancer can be treated successfully if detected early.

Cancer types researched by QIMR Berghofer Medical Research Institute

  • Blood cancers (including leukaemia, lymphoma and myelomas)
  • Brain cancer (glioblastoma)
  • Breast cancer
  • Colorectal (bowel) cancer
  • Endometrial cancer
  • Lung cancer
  • Melanoma
  • Multiple endocrine neoplasia type 1 (endocrine cancer)
  • Nasopharyngeal carcinoma (nose and throat cancer)
  • Non-melanoma skin cancer (actinic solar keratosis, squamous cell carcinoma, basal cell carcinoma)
  • Oesophageal cancer (including Barrett’s oesophagus)
  • Ovarian cancer
  • Pancreatic cancer
  • Prostate cancer
  • Stomach (gastric) cancer

Learn More:  www.qimrberghofer.edu.au Navigating the Cancer Maze is presented by the Grace Gawler Institute for Integrated Cancer Solutions, Gold Coast Australia. We are a not for profit health promotion charity.

Promising Results from World-First Brain Cancer Trials Professor Rajiv Khanna | Grace Gawler on Navigating The Cancer Maze

It is imperative that breakthroughs in cancer treatments are known to the world. Worldwide, there are an estimated 240,000 cases of brain and nervous system tumors diagnosed each year; GBM is the most common, and the most lethal of these tumors. People speak of the War on Cancer, but it is our bodies that are at war with cancer cells via our immune system and its responses. Utilizing the immune system principle, scientists at the QIMR Berghofer Medical Research Institute, Australia, have used immunotherapy to create a major breakthrough in the treatment of the brain cancer known as Glioblastoma Multiforme (GBM).

Free informational cancer seminars Brisbane June 15 – 21 2014 Brisbane.

Click the link below to see other events presented by QIMR – for immunology week June 15 – 21 2014 Brisbane.

How your body can fight cancer Seminars

cancer-lambert_2469736bPromising Results from World-First Brain Cancer Trials Professor Rajiv Khanna Joins Grace Gawler on Navigating The Cancer Maze To Talk about a Brain Cancer breakthrough.

Phoenix, AZ — 06/13/2014 — Voice America Talk Radio Network, Internet broadcasting pioneer, producing and syndicating online audio and video, today announced that Professor Rajiv Khanna QIMR Berghofer Medical Research Institute Australia will join Grace Gawler host of Navigating the Cancer Maze program on the VoiceAmerica Health and Wellness Channel (http://www.voiceamerica.com/show/2125/navigating-the-cancer-maze) Friday, June 13, 2014 at 12 noon Pacific Time.

NOTE: show goes live to air 5 am Brisbane Australia time Saturday 14 June 2014. Available streaming audio any time after 9 am this Saturday and available to download on itunes indefinitely.

It is imperative that breakthroughs in cancer treatments are known to the world. Worldwide, there are an estimated 240,000 cases of brain and nervous system tumors diagnosed each year; GBM is the most common, and the most lethal of these tumors. People speak of the War on Cancer, but it is our bodies that are at war with cancer cells via our immune system and its responses.  Utilizing the immune system principle, scientists at the QIMR Berghofer Medical Research Institute, Australia, have used immunotherapy to create a major breakthrough in the treatment of the brain cancer known as Glioblastoma Multiforme (GBM). Study leader, Professor Rajiv Khanna, said most of the study participants lived much longer than the six-month prognosis normally given to a patient with recurrent GBM, and some patients showed no signs of disease progression. “It is early days, but this is exciting,” Professor Khanna said.

“Survival rates for this aggressive cancer have barely changed in decades. There is an urgent clinical need for new treatments. “If this treatment can buy patients more time, then that is a big step forward.”

GBM
Image of Brain GBM

GBM is the most common malignant brain cancer, diagnosed in about 800 Australians every year.  Despite surgery, radiotherapy and chemotherapy, less than 10% of patients survive beyond five years. This study built on previous research which found that many brain tumours carry cytomegalovirus (CMV). About half of all Australians have the virus, but usually show no symptoms.

Professor Khanna developed a technique to modify the patients’ T-cells in the laboratory, effectively “train” them to attack the virus, and then return them to the patient’s body.  When the killer T-cells destroyed the virus, they also destroyed the cancer. “It’s becoming increasingly clear that immunotherapy – manipulating a person’s own immune system – is a rich new frontier for cancer treatment,” Professor Khanna said.

The QIMR is celebrating their research findings by hosting a series of immunology and cancer presentations between June 15 and June 21 in Brisbane. For those people who cannot attend, watch out on the websites for more information. www.qimrberghofer.edu.au   or  www.gracegawlermedia.com

The Phase I trials were conducted at Brisbane’s Wesley Hospital, under the leadership of neurosurgeon Professor David Walker.  “Working with patients with malignant brain tumors can be distressing, because we know so many will succumb,” Professor Walker said. “But this new branch of therapy lets us offer some hope that the future is going to be brighter, that new and innovative treatments mean things will hopefully improve in the future. “We have a long way to go, and there is hard work to be done, but we seem to be on the right track, and it is a pleasure to work with scientists at QIMR Berghofer to try to make a real difference.”

The research team is now keen to begin the next phase of trials, involving patients at an earlier stage of the cancer’s development. “These would be patients who have just been diagnosed and are about to start the standard treatments – surgery, then radiotherapy or chemotherapy.  We would generate the T cell therapy before their standard treatment, and then administer T cells in conjunction with the standard therapy,” Professor Khanna said.

“We hope that the treatment can be even more effective if given at an earlier stage of the disease.”

This study is published online in the prestigious US journal Cancer Research and can be viewed at http://cancerres.aacrjournals.org/content/early/recent

The research was funded by Flagship Funding from the Rio Tinto Ride to Conquer Cancer, the NHMRC and private donors.

The QIMR Berghofer Medical Research Institute is a world leading translational research institute focused on cancer, infectious diseases, mental health and a range of complex diseases. Working in close collaboration with clinicians and other research institutes, our aim is to improve health by developing new diagnostics, better treatments and prevention strategies.

For more information about QIMR Berghofer Visit: www.qimrberghofer.edu.au

Immunology and Cancer Survival | Navigating the Cancer Maze| Grace Gawler

QIMR Berghofer Medical Research Institute is hosting Immunotherapy week: Get updated about Immunotherapies. Next week QIMR presents a series of lectures about the latest developments in Cancer Immune therapies. QIMR’s Professor Khanna, has been researching immunotherapies and has had a major breakthrough in the treatment of the aggressive brain cancer Glioblastoma Multiforme (GBM).

ATTENTION Queenslanders interested in immune-based Cancer Therapies:  Cancer Immunotherapy Week Brisbane

QIMR Berghofer Medical Research Institute is hosting Immunotherapy week: Get updated about Immunotherapies. Next week QIMR presents a series of lectures about the latest developments in Cancer Immune therapies.

Scientists at the QIMR Berghofer Medical Research Institute have used immunotherapy to make a major breakthrough in the treatment of the aggressive brain cancer Glioblastoma Multiforme (GBM). There will be a presentation on Tuesday evening and other presentations throughout the week.

CLICK HERE FOR MORE INFORMATION

QIMR IMMUNOTHERAPY WEEK
Later this week on Navigating the Cancer Maze I will be interviewing…Professor Rajiv Khanna a leading researcher at The QIMR Berghofer Medical Research Institute, Brisbane, Australia; a world progressive translational research institute focused on cancer, infectious diseases, mental health and a range of complex diseases. Professor Khanna has been researching immunotherapies and has had a major breakthrough in the treatment of the aggressive brain cancer Glioblastoma Multiforme (GBM). Professor Khanna developed a technique to modify the patients’ T-cells in the laboratory, effectively “train” them to attack the virus, and then return them to the patient’s body.  When the killer T-cells destroyed the virus, they also destroyed the cancer. “It’s becoming increasingly clear that immunotherapy – manipulating a person’s own immune system – is a rich new frontier for cancer treatment,” Professor Khanna said. Be informed about the answer to cancer. Support Immunotherapy week- Brisbane Qld. More info at http://www.qimrberghofer.edu.au/

All shows are available in the content Library at Navigating the Cancer Maze on The VoiceAmerica Variety Channel for on-demand and pod cast download. The Grace Gawler Institute is a not for profit health promotion charity providing global access to free information for cancer patients about the latest in cancer information and treatments from experts, patients, caregivers and researchers.

Visit:  http://www.gracegawlerinstitute.com

Black Salve|Holistic or Hole-istic? – Naturopathic Medicine was Never Meant to do This! Grace Gawler

In the Australian Media this week, Medical Reporter Julia Medew writes: A 55-year-old man recently presented to a Brisbane hospital with a black hole in his temple after applying an unproven alternative medicine known as “black salve” to a lesion on his face, which he believed was cancerous. I discussed this media piece and so called remedy in my last segment of Navigating the Cancer Maze on Voice America today.

Holistic or Hole-istic? – Naturopathic Medicine was Never Meant to do This!

In the Australian Media this week, Medical Reporter Julia Medew writes: A 55-year-old man recently presented to a Brisbane hospital with a black hole in his temple after applying an unproven alternative medicine known as “black salve” to a lesion on his face, which he believed was cancerous. I discussed this media piece and so called remedy in my last segment of Navigating the Cancer Maze on Voice America today.

BLACK SALVE
Results of Using Black Salve

Writing in the Medical Journal of Australia, doctors from the Princess Alexandra Hospital said the man had been applying the unlicensed product, which is sold online as an alternative skin cancer treatment, to his face for four months.

The doctors, Natalie Ong, Eric Sham and Brandon Adams, said black salve preparations often contained an alkaloid derived from bloodroot and zinc chloride which could both eat away at tissue, leading to significant scarring and disfigurement. “In the absence of a biopsy, some patients may commence alternative treatment before attaining a diagnosis of skin cancer, and a very real risk of recurrence and metastasis (cancer spreading) remains….

Having worked with cancer patients for most of my naturopathic life; I am well aware of the nature of cancer and the inherent dangers in applying Black Salve to human or animal tissues. Far too many times I have seen first hand the destruction caused by this so called natural remedy.

( Folks there is nothing natural about zinc chloride which is often compounded with Bloodroot to create the paste – that is recommended to be applied to many different types of skin lesions). Zinc Chloride is an escharotic and tissue fixative; not to messed with! It is claimed by proponents that “the cancer salve made from zinc Chloride and Bloodroot is safe and effective, and has never harmed anyone, in thousands of years of use”.

The photograph above is just one small example of the damage I have seen from applying this paste. Cancer patients have used it on breast tumors, all kinds of skin tumors malignant and benign. One client used it on her genital area for an SCC ( squamous cell carcinoma)! The erosion and pain was horrendous. My own patient records with photographs of tissue damage are vile viewing. Many melanoma patients are delaying treatment  due to this remedy and their belief in it to “cure cancer”. Professor Dr Alexander Herzog, Germany keeps a photo album of the black salve disasters he has to try to repair when it all goes belly-up for patients. Gaping holes in breast tissue, some  large enough to insert a fist are displayed page after page…and then there is the mother who applied the Black Salve paste to a  melanoma located on her son’s skull. She used the paste for 6 months – you could see his brain through the hole! Professor Herzog says he cant understand why cancer patients are using this paste.

The whole history of  Moh’s chemo-surgery – margin controlled microscopic surgery using zinc Chloride – an interesting read.

http://www.skincancer.org/skin-cancer-information/mohs-surgery/evolution-of-mohs

What is about this preparation that gives it allure? Is it the mystique of purported native American history? Is it the supposed safety level that is claimed? Is it because a former Hollywood movie star has promoted it?  Is it because we hate science and love cottage medicines?

Scab created by black salve
Scab created by black salve

The allure has even defied logic as many of Naturopathic friends, not only cancer patients believed in the salve to the extent that the paste “got it all” only to die from their metastatic melanoma and squamous cell carcinomas. Why is it that even bringing science and logic to this preparation will generate hate mail?

Personally I am tired of attending Black Salve funerals. I am glad it is banned in Australia however you can find it all around the internet still and even in the back end under the counter of some health food stores! My best advice – DON’T GO THERE! First and foremost – Find out what you are dealing with before embarking upon any treatment and please realize that this can be a sinister remedy with associated complications that make chemotherapy side effects look like a walk in the park!

In 2012, the Therapeutic Goods Administration warned people to avoid black salve, which is also known as red salve, Cansema, or Bloodroot.

More coming soon about discussions from today’s Navigating the Cancer Maze on Voice America- please visit again……

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Learning from True Survivors|Marala Scott Oprah’s Ambassador for Hope and David Tuccaro Jr.

We can learn from true survivors. It does not have be a cancer crisis – any crisis will do! When we learn from true survivors; we make deposits into our “Life Bank Account”. When in “credit” we have either acquired or learned skills as resources to help us navigate life’s crisis maze. Marala Scott is a storyteller and recently she authored the story of David Tuccaro Jr in Bad to the Bone whom I interviewed on Navigating the Cancer Maze Voice America Radio. Marala Scott has also shared her unimaginable life story to help others learn to forgive, accept challenges and adapt to changes in life, chronicled in her bestselling memoir, In Our House: Perception vs. Reality (an Amazon Best Seller).

What can we learn from true survivors? It does not have be a cancer crisis – any crisis will do!

David Tuccaro Jr and Marala Scott Oprah's Ambassador for Hope
David Tuccaro Jr and Marala Scott Oprah’s Ambassador for Hope

When we learn from true survivors; we are enabled and empowered to make deposits into our “Life Bank Account”. Crises can occur at any time in our life. We are often unprepared. When our “Life Bank Account” is in “credit”; we have either acquired or learned skills that we can access and utilize as resources, if and when we need to navigate life’s crisis maze. Without these skills, crises can become deep seated traumas that affect quality of life.

Marala Scott is a storyteller and recently she authored the story of David Tuccaro Jr in Bad to the Bone. If you missed the interview with David on Voice America Radio CLICK HERE TO LISTEN:

Marala Scott is a Multi Award-winning Author, Motivational Speaker, Ghostwriter and Oprah’s Ambassador of Hope who shares powerful words of inspiration wherever she goes.

Marala has shared her unimaginable life story to help others learn to forgive, accept challenges and adapt to changes in life, chronicled in her bestselling memoir, In Our House: Perception vs. Reality (an Amazon Best Seller) and Surrounded By Inspiration. The newly released book, Bad to the Bone: The True Story of David Tuccaro Jr. (an Amazon Best Seller) is a heart-wrenching story that inspires you to believe when there is no evidence of hope.

Marala Scott speaks from the heart with her life-changing words of faith and strength. Her efforts caught the attention of Oprah Winfrey, who honored her as one of her five Ambassadors of Hope in 2009 and stated, “A childhood of abuse almost kept Marala Scott from a life of happiness…until she discovered how to use her story to help others.” Ms. Scott is also a recipient of a Congressional award, among many others, for her humanitarian efforts for sharing her prolific life story in efforts to help and inspire others. Ms. Scott is a widely sought after Ghostwriter at Seraph Books that helps share the inspiration others have experienced with their power and passion.

More about David Tuccaro Jr’s Story: http://www.davidtuccaro.com/#

READ PRESS RELEASE AT:

http://vapresspass.com/2014/03/26/david-tuccaro-leukemia-survivor-talks-bad-bone-memoir-marala-scott-navigating-cancer-maze-grace-gawler/ 

Voice America Grace Gawler