Grace Gawler Learning the Art of Survivorship | How to Navigate the Cancer Maze

The cancer journey begins with one step – diagnosis. Learn how to walk the path to Survivorship. Remember that there is no substitute for early diagnosis and intervention in Survivorship. The aim of today’s Navigating the Cancer Maze internet radio show is to help you find a path through the cancer maze by learning how to become an exceptional patient with the possibility of living through and beyond cancer.

The cancer journey begins with one step – diagnosis. Learn how to walk the path to Survivorship. Remember that there is no substitute for early diagnosis and intervention in Survivorship. The aim of today’s Navigating the Cancer Maze internet radio show is to help you find a path through the cancer maze by learning how to become an exceptional patient with the possibility of living through and beyond cancer. Like many of life’s major crisis events; cancer is a daunting prosjourney of a thousand miles begins with one small steppect. In order to survive and thrive; a cancer diagnosis requires you to learn & develop a new skill set; a new way of prioritizing self, time to deal with the trauma of diagnosis and what it might mean for you in terms of accepting change, being adaptable and flexible. Decisions can feel overwhelming because your life depends upon those decisions & the consequences of making them.
There is an immediate need to focus, plan, question, set goals, prepare for setbacks etc.

Whether or not you are first time cancer patient or dealing with a second or third recurrence, if you have been battling on your own – there can still be much to learn.

Find an experienced cancer navigator to help you along the way.

Be effectively  case managed and take the extra stress out of cancer.

FREE chapter download: As mentioned on today Navigating the Cancer Maze.
The Three Essential Stages of healing:  Select URL below for PDF
Insights of a Survivor who has known Survivors as mentioned on today Navigating the Cancer Maze internet radio.

Defining Survivorship
Surviving cancer or “survivorship” can be defined in different ways. Two common definitions include:
• Being disease-free after the completion of treatment,
• Living with, through, and beyond cancer includes people who continue to have treatments to either reduce risk of recurrence or to manage chronic disease. By this definition, cancer Survivorship begins at diagnosis and survivorship is a state that continues throughout your life.
• Bernie Siegel described this group as EXCEPTIONAL Cancer Patients.

Because we are talking about the precious lives of cancer patients – as a part of today’s subject, I hasten to add here that it is important for those interested in surviving cancer that I discuss where NOT to put your energy if you want to be a survivor. Yes modern medicine is not perfect – but it is the best we have and it it is improving all the time.

If you are seeking Survivorship through and beyond cancer – please use every means possible from the best that conventional medicine has to offer in combination with the best of scientific complementary medicine and complementary therapies.

baby-bathwaterPlease “Don’t throw the baby out with the bathwater”! Conventional medicine is a gift. Cancer is tricky – you can’t outsmart it with juices, meditation and positive thinking. How “you be” with a cancer diagnosis – i.e. – your attitude, strategies, will to live and will to heal – contribute tremendously – but you need to partner with the best that conventional medicine has to offer. If cancer patients understood the scientific basis of cancer – how it behaves and operates for it’s own survival; different choices might be made- conquering cancer is not that simple!

 I must mention Jess Ainscough here because of the influence she has had on cancer patients young and old in terms of promoting one type of Survivorship approach. Surviving through and beyond cancer is not the simple 123 steps that entrepreneurs such as Jess promoted.

Cancer entrepreneurs like Jessica Ainscough AKA The Wellness Warrior has influenced thousands, maybe millions to take the alternative path to cancer healing. Sadly it all went wrong for her mother who had breast cancer. She died last year. Jess remained struggling with advancing fungating cancer until this week when she died from her epitheloid sarcoma. Sadly I see patients like Jess every week. I conduct an Alt med cancer rescue practice with my Specialist GP colleague Dr Whelan. We see so many scales-of-justicepatients influenced to take the natural path to cancer recovery – influenced by Dr Google and the plethora of misleading books by cancer entrepreneurs.

Jess became a crusader for the Gerson diet and might I add, was also influenced by my ex-husbands ‘cancer recovery’ story. During the past few years his story has been challenged by myself and more recently; by two Melbourne oncologists who published their findings in the internal Medicine Journal. Once they discovered there was no biopsy performed for Ian’s condition at the time which was thought to be secondary bone cancer they began an independent investigation into why he recovered. In 1978, here was no other explanation offered and to all and sundry it appeared as though the impossible had been achieved – a full remission from metastatic osteogenic sarcoma. However with a thorough review and missing pieces of the Gawler healing puzzle put in place – a new diagnosis was suggested.  IMJ HAINES AND LOWENTHAL

Jess Ainscough’s approach to her cancer was clearly influenced by Ian Gawler’s recovery, the diagnosis which was highly likely to have been advanced TB with calcified abscesses – not metastatic bone cancer as had been reported over the decades. (see the menu for more on this subject).

The late Jess Ainscough wellness warrior gawler gerson
The late Jess Ainscough wellness warrior

 Importantly –  If that is so – then the basic premise and promise upon which Jess Aincough based her recovery from cancer plan was false. Jess was quoted as saying: ” Ian Gawler was diagnosed with bone cancer and had his right leg was amputated in 1975. However, the disease recurred later that year and began ravaging his body. Ian’s story of recovery, employing an integrated approach driven predominantly by dedicated meditation, is truly remarkable. It was my anchor to a future the doctors had pretty much ruled me out of having. I thought, If Ian can do it, so can I. His book, You Can Conquer Cancer, was my Bible”. Source:  JESS ainscough Gawler healthtalks;

Clearly patients like Jess are looking for options and they will often choose the seemingly softer options that the one size fits all alternative approach offers. Cancer education is imperative and sadly lacking in the patient world. Cancer is not a generic disease that can be simplistically tackled with food and copious juices. I think this is a very sad indictment of what true Survivorship is really all about. Like many of the patients I see in my practice, Jess Ainscough only embraced conventional medicine when the path she had followed failed her.
It is my hope that Jess Ainscough’s story and life serves as a teaching story for all who want to walk the path to cancer Survivorship – please use critical thinking to assess information on the internet and consider a best of both worlds approach for best outcome.

More on Wellness Warrior: ORAC ( Oncology surgeon) – Science based Medicine Below:
http://scienceblogs.com/insolence/2014/12/16/jess-ainscough-finally-admits-her-condition-is-deteriorating/

http://scienceblogs.com/insolence/2013/10/17/sharyn-ainscough-dies-tragically-because-she-followed-the-example-of-her-daughter-the-wellness-warrior/#comment-297256

http://scienceblogs.com/insolence/2015/02/27/the-wellness-warrior-jess-ainscough-has-passed-away/

The following Survivorship links will be helpful:

 http://www.cancerbridges.ca/

http://www.amazon.com/Survivorship-Living-During-After-Cancer/dp/1938170350

SURVIVOR TRAINING COURSE: Queensland

http://www.gracegawlerinstitute.com/survivor-training/

Listen to Navigating the Cancer Maze – Today’s show.
http://www.voiceamerica.com/episode/83721/learning-the-art-of-survivorship-how-to-navigate-the-cancer-maze

Until next time – Be safe in your choices – cancer is a tough opponent- choose your course wisely!

Grace

Which Scan should I have – Navigating the Medical Imaging Maze

Each week in my team consultation practice with specialist GP Dr Bruce Whelan; we hear grave concerns from patients about the radiation risks from diagnostic scans. Unfortunately many cancer patients say no to two imperative diagnostics tools; biopsies and scanning procedures.

Each week in my team consultation practice with specialist GP Dr Bruce Whelan; we hear grave concerns from patients about the radiation risks from diagnostic scans. Unfortunately many cancer patients say no to two imperative diagnostics tools; biopsies and scanning procedures. Usually this is a result of consulting the doctor who never sees a patient and offers a one size fits all approach – yes it’s Dr Google! It is true that medical scans are a source of radiation – however the Health intelligence australiabenefits of knowing as much as possible about your cancer and where it might be located in your body far outweigh the risks. Death from Cancer is not such a great option either I tell my clients.

This is why I interviewed Dr Nevil Chimon on Navigating the Cancer Maze internet radio Select this link to listen

Dr Nevil Chimon researches and develops radio tracers for medical imaging. The science, processes & advances of imaging techniques, & the radio-pharmaceuticals that magically make our inner parts visible to doctors for more accurate diagnosis; is the topic for today’s Navigating the Cancer Maze. Dr Nevil Chimon shares his passion and invaluable information for cancer patients about the different types of cancer & the best medical imaging to assist diagnosis. This is information that you need to know! All patients become intimately involved with the process of cancer imaging, & the relationship often lasts for 5 or more years.

BIOGRAPHY:  Dr Chimon is a medical science graduate of UCLAN, BSc (Hons), Manchester University, MSc & NUS, PhD, with Post-Doctoral training in Molecular Imaging & Radiochemistry completed at the Paterson Institute for Cancer Research & Wolfson Molecular Imaging Centre, UK. Nevil has over 10 years of experience within the pharmaceuticals industry. Holding positions of increasing responsibility within MNCs and SMEs has provided him with broad exposure to projects involving drug discovery & imaging diseases, including cancer & dementia. Strategically, he recognizes an opportunity exists to leverage on molecular imaging technology to both accelerate drug discovery and improve the healthcare of patients by using PET-CT and PET-MRI multi-modality imaging.

Dr Nevil Chimon BSc (Hons), MSc and NUS, PhD,
Dr Nevil Chimon BSc (Hons), MSc and NUS, PhD,

During his 7-years based in Singapore, Dr Chimon has established the first Preclinical CRO imaging facility, obtained GMP licensing for the RadLink cyclotron facility, performed the first clinical trial with a proprietary radio-tracer for Bayer Pharmaceuticals, & manufactured new tracers to detect cancer. To Listen to my interview with Dr Nevil Chimon: CLICK HERE

As a Cancer Patient – You need to Know your imaging options so you make an informed choice:

Different imaging methods use different technology and provide different types of images. This means they have different benefits for showing what is happening inside the body (e.g. for showing bone, soft tissue or tumours). Imaging methods also have different potential advantages and disadvantages, including exposure to radiation.

Here are just a few of the New Scanning devices and procedures  you need to know about:
Prostate CancerPSMA (Prostate Specific Membrane Antigen) PET-CT – A PSMA study, also called a ProstaScint® scan, is an imaging test to locate and determine the extent of prostate cancer. PSMA studies are performed on newly diagnosed prostate cancer patients to determine if the disease has spread to pelvic lymph nodes. The study is also performed on patients who have had their prostate gland removed (prostatectomy) and have an increase in prostate-specific antigen (PSA) blood levels.

The study involves a special molecule called a monoclonal antibody developed in a laboratory and designed to bind to the prostate-specific membrane antigen on cancer cells. This antibody is paired with a radioactive material called Indium-111 that can be detected by a gamma camera. When injected into the patient’s bloodstream, the radioactive antibody travels and attaches to cancer cells. The gamma camera then produces three-dimensional images of the tumor and its location inside the body. This study is performed over as many as three days. On the first day, the patient first receives an intravenous (IV) injection of the radioactive antibody. Imaging is performed in two sessions, separated by 24 or more hours. Each imaging session will last between two and four hours. The camera rotates around the patient, who remains still.

  • Molecular imaging and prostate cancer? Molecular imaging is used to:
    stage treatment: by determining the exact location of a tumor, the extent or stage of the disease and whether the cancer has spread in the body and plan treatment by selecting the most effective therapy based on the unique molecular properties of the disease and of the patient’s genetic makeup
  • Choline C-11 PET scan is an imaging test used to help detect sites of prostate cancer that have returned despite treatment (recurrent prostate cancer). It may be used when other imaging has not been helpful. Choline C-11 PET scan is a positron emission tomography (PET) scan that uses a special chemical tracer called Choline C-11 Injection.
  • Valuable links:
    11E_The use of Choline PET_CT in prostate cancer imaging_Tara Barwick
    SCANNING FOR PROSTATE CANCER

    Targeted therapies offer new options for prostate cancer treatment
  • Breast Cancer:  MRI:  Some women, particularly those under the age of 50 and who are at high risk of developing breast cancer due to a strong family history or a genetic mutation, are encouraged to undergo annual breast Magnetic Resonance Imaging (MRI) as part of their regular screening routine. MRI is sometimes a more effective screening tool for younger women, especially those with dense breasts. MRI scans are very expensive — up to $700 AUD per scan. There is a Medicare rebate for women at high risk of developing breast cancer.
  • Mammograms A mammogram is an X-ray of the breast and is the most common form of breast imaging. There are two types of mammogram — screening and diagnostic.
    Screening mammograms: Screening mammograms are used for women who do not have any symptoms of breast cancer and who have not had breast cancer in the past. If you are aged 40 or over, have never been diagnosed with breast cancer and currently have no symptoms of breast cancer, you can be screened free of charge at a BreastScreen Australia clinic.
    Diagnostic Mammograms Diagnostic mammograms are recommended for women who have a previous history of breast cancer or who are at high risk of developing breast cancer. Several X-rays are taken in order to obtain views of the breast/s from different angles. You will need a referral from a doctor for a diagnostic mammogram.
  • More info at http://www.bcna.org.au/living-breast-cancer/follow-care/breast-imaging

Diagnosing NETS (neuroendocrine tumours).

  • Ga68 DOTATE is a somatostatin receptor agent used in the imaging of well-differentiated neuroendocrine tumours. For poorly differentiated neuroendocrine tumours; standard F18 FDG-PET remains the imaging of choice for diagnosis. Dr Nevil Chimon discusses NET imaging options and the latest developments in my interview with him on Voice America.

Different types of imaging

  • X-rays (plain radiography) – Uses X-rays to show images of bones, tumours and other dense matter
  • Advantages: Quick, non-invasive and painless
    Can help diagnose various diseases and injuries, including broken bones, cancer and infections
    Disadvantages: Very small increased risk of cancer in future from exposure to ionising radiation (x-rays). Risk is greater for children
  • Computed tomography (CT scans) Uses multiple X-rays to produce cross-sectional layers that show detailed images inside the body, including bones, organs, tissues, and tumours.
    Advantages*Quick and painless
    *Can help diagnose and guide treatment for a wider range of conditions than plain X-rays
    *Can detect or exclude the presence of more serious problems
    *Can be used to check if a previously treated disease has recurred
    Disadvantages*Small increased risk of cancer in future from exposure to ionising radiation (X-rays). Risk is greater for children
    *Uses higher doses of radiation, so the risks (while still small) are in general greater than other imaging types
    *Injection of a contrast medium (dye) can cause kidney problems or result in allergic or injection-site reactions in some people -Some procedures require anaesthesia.
  • Nuclear medicine imaging including positron-emission tomography (PET) Involves injecting, inhaling or swallowing a radioactive ‘tracer’. The gamma-rays emitted by this material are used by the scanner to show images of bones and organs:
    Advantages*Usually painless
    *Can help diagnose, treat, or predict the outcome for a wide range of conditions
    *Unlike most other imaging types, can show how different parts of the body are working and can detect problems much earlier
    *Can check how far a cancer has spread and how well treatment is working
    *Involves exposure to ionising radiation (gamma-rays)
    Disadvantages A PET scan can take 3 to 4 hrs from arrival to departure
  • *Radioactive material may cause allergic or injection-site reactions in some people
    *PET scanners cause some people to feel claustrophobic, which may mean sedation is required
  • Magnetic resonance imaging (MRI) Uses magnetic fields and radio waves to show detailed images of organs, soft tissues, bones, ligaments and cartilage
  • Advantages*Usually non-invasive and painless
    *Uses no ionising radiation
    *Can help diagnose and guide treatment for a wide range of conditions
    *Can provide similar information to CT in some types of investigations
    Disadvantages*Can be a lengthy and noisy procedure
    *Slight movement can ruin the image, requiring retesting
    *Can make some people feel claustrophobic
    *Sedation or anaesthesia may be required for young children or others who can’t remain still
    *Injection of a contrast medium (dye) if needed can cause kidney problems or result in allergic or injection-site reactions in some people
    Can’t be undertaken in some situations (e.g. when a heart pacemaker is present)
  • Ultrasound Uses high-frequency sound waves to produce moving images onto a screen of the inside of the body, including organs, soft tissues and bones
  • Advantages*Usually non-invasive, safe and relatively painless
    *Uses no ionising radiation
    *Does not usually require injection of a contrast medium (dye)
    *Can help diagnose a range of conditions in different parts of the body, such as the abdomen, pelvis, blood vessels, breast, kidneys, muscles, bones and joints
    Disadvantages*Quality and interpretation of the image highly depends on the skill of the person doing the scan
    *Other factors can affect image quality, including the presence of air and calcified areas in the body (e.g. bones, plaques and hardened arteries), and a person’s body size
    *Use of a special probe (e.g. for the oesophagus, rectum or vagina) is required in some ultrasounds
    *Special preparations may be required before a procedure (e.g. fasting or a full bladder)
  • Bone scan? A bone scan is a diagnostic imaging test used to determine whether cancer has spread to the skeleton. A tiny amount of radio-tracer is injected into the patient’s bloodstream and accumulates predominantly in the bones where it can be detected by a specialized imaging device called a gamma camera. The resulting two-dimensional or three-dimensional images can reveal various processes such as bony fractures, infection or inflammation or the likely presence of cancer cells.

Select the following URL to learn about the impact of radiation from Medical Scanning:
http://www.radiologyinfo.org/en/safety/?pg=sfty_xray

Medical imaging and Theranostics (developing molecular diagnostic tests in tandem with targeted therapeutics) are medical sciences that are moving forward at a rapid pace.  Ask your oncologist/radiologist for the latest information about new  scanning machines and techniques for your particular type of tumour.

We see many patients who have foregone critical diagnostic scans due to fears about radiation from scanning devices; mainly after reading  poorly researched information on Dr Google. All cancer situations need proper diagnosing and monitoring. Most medical scans carry a small long term risk from radiation exposure – but to not know about a burgeoning cancer is a far greater risk to life and longevity.

If you need assistance and case management – you can consult with myself and specialist GP Dr Bruce Whelan in a team consultation at our Gold Coast, Qld Practice. I am also available for Skype consultations for distance Clients – We are able to offer world-wide referrals. To Contact myself and Dr Whelan:  Email institute@gracegawler.com

Until next Time….

Grace

How to ride the new wave of immune therapies | Prof Brendon Coventry and Jill O’Donnell-Tormey PhD Show the Way

Good news on cancer: There is a definite change in the wind! The face of oncology is changing. Both cancer patients and oncologists are undergoing a cancer metamorphosis. Treatments are moving – albeit slowly from a killing cancer focus to a focus on retraining the body’s own immune system to seek and destroy cancer cells.

Good news on cancer: There is a definite change in the wind! The face of oncology is changing. Both cancer patients and oncologists are undergoing a cancer metamorphosis. Treatments are moving – albeit slowly from a killing cancer focus to a focus on retraining the body’s own immune system to seek and destroy cancer cells.

Riding the wave of new immune therapies. Pic: ABC News
Riding the wave of new immune therapies. Pic: ABC News

Last week on Navigating the Cancer Maze internet radio Prof Brendon Coventry spoke about cancer vaccines and in particular about his success treating advanced melanoma.

He also spoke about the importance of measuring a patient’s immune cycle as a new approach to that value-adds to the “New Wave” of immunotherapy treatments against cancer.

Click here to listen to that interview if you missed it – (live streaming or download on itunes to listen later at no cost).

Questions from cancer patients clearly demonstrate a thirst for knowledge about immune therapies.

Therefore – today – I have replayed my interview from mid last year(2014) with Cancer Research Institute’s CEO Jill O’Donnell-Tormey PhD.  Click Jill’s name to be redirected to the interview on Voice America internet radio. In this interview Jill provided a clear picture of where immune therapies are headed and what they actually do and where you can find trials and treatments.
VISIT:  http://www.theanswertocancer.org/

Jill talks about the new immunotherapy pharmaceuticals – an innovative class of drugs that block PD-1.  (Stands for programmed cell death protein 1). PD-1 inhibitors, activate the immune system to attack tumors and are therefore used to treat cancer.  These drugs have complex names such as nivolumab successfully used in non-small-cell lung cancer, melanoma, and renal-cell cancer; Pembrolizumab; intended for use in treating metastatic melanoma; to name but a few. Then there are CTLA-4 antibodies such as Ipilimumab; a fully human, monoclonal antibody that overcomes CTLA-4–mediated T-cell suppression to enhance the immune response against tumors.

Anti-PD-1 and Anti-PD-L1 Antibodies – Unlike CTLA-4 antibodies, the PD-1/PD-L1 antibodies aim to potentiate the antitumor T-cell response at a tumor-specific level, by impairing the interaction of the inhibitory receptor PD-1 on T cells with PD-L1 expressed on tumor cells

Cancer patients as well as doctors and oncologists are having to learn a new language and a new way of thinking about cancer. The process is slow – but the most important people in cancer medicine –  patients; need to know the basics and what to ask of their oncologists because these new immune drugs, cancer vaccines and immune timing of treatments, appears to hold the key to curing cancers.

As I see it – the only caution right now is that patients may be rushing to overseas alternative clinics who promote the new elaborate cocktails of immune therapies. Skill and experience is required in using these new immune treatments- best to ask an expert.

Now – back to Prof Coventry and Martin Ashdown’s work for some additional information….
There are many studies that demonstrate that conclusions made by Prof Brendon Coventry and Martin Ashdown that propose that our immune system has a rhythm that can be measured especially when a patient has advancing cancer.

T lymphocytes (orange colour) assembling to kill cancer
T lymphocytes (orange colour) assembling to kill cancer

 It is known that Cytokines (cell signalling molecules that aid cell to cell communication in immune responses and stimulate the movement of cells towards sites of inflammation, infection and trauma), are crucial mediators for shaping immune responses. Cytokines are important regulators of both the innate and adaptive immune response.

The following from the Journal of Immunology Research 2014 – states that Several parameters of the immune system exhibit oscillations with a period of approximately 24 hours that refers to “circadian rhythms.” Such daily variations in host immune system status might evolve to maximize immune reactions at times when encounters with pathogens are most likely to occur. However, the mechanisms behind circadian immunity have not been fully understood. Recent studies reveal that the internal time keeping system “circadian clock” plays a key role in driving the daily rhythms evident in the immune system. Importantly, several studies unveil molecular mechanisms of how certain clock proteins (e.g., BMAL1 and CLOCK) temporally regulate expression of cytokines. Since cytokines are crucial mediators for shaping immune responses, this review mainly summarizes the new knowledge that highlights an emerging role of the circadian clock as a novel regulator of cytokines. Continue reading “Review Article
Temporal Regulation of Cytokines by the Circadian Clock” at: http://www.hindawi.com/journals/jir/2014/614529/

Research such as the above; should encourage us to support the important work on immune synchronization and timing of cancer treatments recently pioneered by Prof Brendon Coventry (and Martin Ashdown) as featured on my internet radio show: Navigating the Cancer Maze 23 January 2015; please see interviews and links below.

Biological_clock_human_svgProfessor Coventry’s first interview listed on the Science show with Robin Williams was broadcast : Saturday 17 April 2010 !! At last there is an intervention that can positively impact outcomes of treatments and that is relatively non invasive (apart from a series of blood tests over a 2 week period).

The information graphed from results can tell you when your window of opportunity for optimum response from your cancer treatments will be. It is my hope that patients will take the time to read and understand the research on both the immune system and immune synchronization of cancer treatments and its exciting implications and begin to ask for their immune systems rhythm to be measured and evaluated.

Prof Brendon Coventry Adelaide, South Australia
Prof Brendon Coventry Adelaide, South Australia

Prof Brendon Coventry says immune system rhythm, may be a fundamental discovery. Implications are better health and reduced costs for the health system. A survey showed that tumours disappear completely in just 7% of patients when treated with chemotherapy. Did the time of administering chemotherapy have an effect? Daily blood measurements show fluctuation in inflammatory markers in the blood. A cycle emerged. It’s now thought the immune system is being regulated, being switched on and off against the tumour. The periodicity is roughly 7 days. This matters, as hitting the immune system with chemicals when it isn’t receptive might be ineffective.

For more information visit the following URLs

Melanoma Study:

http;//www.immunotherapyofcancer.orgcontentpdf2051-1426-2-9.pdf

Immune System pulsing – Timing of Treatment

Martin Ashdown Window of Opportunity1

Be a particicipant in the medicines and approaches that could save your life!

until next time…..
Grace

Why Innovative Oncology is an Effective Way to Tackle Cancer

Today on Navigating the Cancer Maze I speak with Prof Brendon Coventry about melanoma and in particular, vaccines against melanoma. But more than a melanoma treatment, Cancer Vaccines are showing up as not only as a part of innovative and integrated oncology approaches; but as likely treatments for other types of cancers that have failed conventional treatments such as radiation and chemotherapy protocols.

Today on Navigating the Cancer Maze I speak with Prof Brendon Coventry about melanoma and in particular, vaccines against melanoma. But more than a only a melanoma treatment, Cancer Vaccines are showing up as not only as a part of innovative and integrated oncology approaches; but as likely treatments for other types of cancers that have failed conventional treatments such as radiation and chemotherapy protocols. For example Jeffrey Deslandes, who after 4 recurrences of NH lymphoma – found his success with cancer vaccines. He is 9 years clear of the disease.

Prof Brendon Coventry with Grace Gawler
Prof Brendon Coventry with Grace Gawler

 The combination of Surgical Oncologist  in combination with a PhD in Immunology – is rare; but this is what Prof Coventry brings to the cancer “treatment table”. He has many years experience in cancer research, vaccine therapies and the role of the immune system in cancer control.

To Listen to audio of show – 4 sessions – select  each link below

Listen to Navigating the Cancer Maze-with Prof Brendon Coventry

Sessions one to four  with

Remember the show is for you and sponsored by our charity – The Grace Gawler Institute. It is free to air and free to listen live streaming within an hour of live broadcast. It is archived indefinitely on my Voice America Page. Crucial to the shows intention – to educate patients and families about the availability of  scientifically valid cancer treatments and safe and effective complementary medicine; we ask that you forward the ecard (available on the website) or URL to those you know who are trying to navigate the increasingly complex cancer maze.

Every week, some 160,000 people die of advanced cancer around the world, despite our best attempts at cancer treatment globally. Some $32 billion is being spent on oncology drugs and the USA National Cancer Institute/ NIH spends about $5.2 billion on cancer research, per annum. Sadly, cancer has remained a tremendously costly public health problem of major proportions for over 5 decades, and our progress has been puzzling slow towards solving this using standard methods.

On today’s show, Navigating the Cancer Maze, my guest Professor Brendon Coventry, an Adelaide-based oncology surgeon suggests there may be another way to approach the problem and shows that the immune system my hold the answer. With a special interest in Melanoma Surgery, he is a clinical researcher whose interests include anti-tumour immune response in human malignancies, tumour Immunology and cancer vaccine treatments.

His group’s research paper, published in 2014, entitled “Vaccinia Melanoma Cell Lysate Vaccine (VMCL) Trial for treatment of advanced Stage IV Melanoma with and without Chemotherapy”, captured the attention of medical and scientific community. Trial conclusions reported high complete response rates (where all cancer disappears) of 17%, with useful clinical responses occurring in nearly 80% of patients overall (slowing the disease), and over 15% of patients experiencing survivals past 5-years, with essentially no toxicity. The longest survivor now remains alive for over 14 years. These response rates and survivals are unusual for advanced melanoma. The researchers reason that the repetitive and prolonged delivery of the vaccine therapy might hold part of the clue, because this was a strikingly different approach to that used in other trials.

At this weeks Meeting of Minds in Brisbane Prof Coventry with Grace Gawler and Martin Ashdown
At this weeks Meeting of Minds in Brisbane (LtoR) Martin Ashdown with Grace Gawler and Prof Coventry

Prof Coventry with colleague Martin Ashdown, have now developed a remarkable understanding of how the human immune system continuously oscillates in a dynamic fashion. The timing of ‘when’ the therapy dose is precisely delivered in synchrony with each individual patient’s own immune system waveform or cycle might hold the very key to improving cancer treatment, thus leading to better survival.

Martin Ashdown says: …..”The concept of immune monitoring and accurately synchronizing therapy (immune synchronization), brings a new level of science to oncology. The published mouse experiments and human clinical trials, together with our knowledge of physiology tells us this is the way forward, particularly with the new cancer immunotherapies. This approach potentially has the triple benefit of increasing efficacy, lowering toxicity and substantially reducing the cost of treatment”

Professor Brendon Coventry is well crendentialled

Professor Brendon Coventry BMBS, PhD, FRACS, FACS, FRSM is an Associate Professor of Surgery at the University of Adelaide and Senior Consultant Surgeon (General, Breast-Endocrine, Surgical Oncology & Trauma Surgery) at the Royal Adelaide Hospital since 1993.

He holds a PhD in cancer immunology.

Positions:
• Immediate Past Chairman, Surgical Oncology Section, Royal Australasian College of Surgeons;
• Research Director, Australian Melanoma Research Foundation & Board Member;
• Past Chairman, Melanoma and Skin Cancer Group, Clinical Oncological Society of Australia;
• Foundation Chairman, Multidisciplinary Melanoma Management Group, Royal Adelaide Hospital
• Senior Examiner, Australian Medical Council
• Board Member of Cancer Care Centre, Unley

Fellowships:
• Royal Australasian College of Surgeons,
• American College of Surgeons
• Royal Society of Medicine.

Research:
• Over 85 journal publications; including New England Journal of Medicine, British Journal of Cancer, Journal of Clinical Oncology, Lancet Oncology; widely published topics including surgical treatment for melanoma and breast cancer, sentinel node surgery, sarcoma surgery, adjuvant radiation therapy, melanoma vaccine therapies,laparoscopic spleen surgery techniques, neuroscience, microscopic methods, high-sensitivity tissue immunochemistry, public health,
medical education, internet learning.
• NIH Principal Investigator: Multicenter Selective Lymphadenectomy Trial (MSLT-I) surgical sentinel node; C-Vax melanoma vaccine studies (x2).
• Editor-in-Chief, 7-Volume international textbook series “Surgery: Complications, Risks and Consequences” published by Springer; general adult, paediatric and cardio-vascular surgery.
Current Research:
• Surgical Complications, Safety and Quality improvement
• Vaccine Therapies for Advanced Melanoma, novel findings from repetitive dosing where 5-year survival and Complete Response rates have been significantly improved
• Timing of Therapies is novel collaborative work with Martin Ashdown concerning serial blood biomarker monitoring for advanced cancer patients for more accurate timing to improve therapy dose delivery and clinical efficacy further, which is gaining recognition

 

More on Vaccine successes – listen to Jeffrey Deslandes interviewed on Juice radio – Gold Coast yesterday 16 January 2015. https://soundcloud.com/juice-107-3/cancer-survivor-jeffrey-deslandes

Sometimes we can’t make financial donations for a cause – but we can use the internet, emails social media and word of mouth to help bring about change. Patient demand through critical need will make a difference- but voices are required! Please spread the word about this interview and the show and make your contribution to change the paradigm of treating cancer for the benefit of humanity.

Until next time
Grace

Cancer Experts Discuss Cancer Vaccines and Immune Cycle Timing of Treatments in Brisbane

Cancer vaccines and immune cycle timing: Hear Prof Brendon Coventry and Martin Ashdown on 612 ABC radio Brisbane, Queensland with Steve Austin today 10.30am Tuesday 13 January 2015. State-wide broadcast. Listen or Download later as a podcast at: http://www.abc.net.au/brisbane/programs/612_morning/

Cancer vaccines and immune cycle timing: Hear Prof Brendon Coventry and Martin Ashdown on 612 ABC radio Brisbane, Queensland with Steve Austin today 10.30am Tuesday 13 January 2015. State-wide broadcast. Listen or Download later as a podcast at:

http://www.abc.net.au/brisbane/programs/612_morning/

A MEETING OF MINDS – EXPLORING FURTHER RESEARCH & DEVELOPMENT OF • Cancer Vaccines in

Prof Brendon Coventry Adelaide, South Australia
Prof Brendon Coventry Adelaide, South Australia

Australia & Immune Synchronisation of Cancer treatments is organised by my Institute. The Grace Gawler Institute is always looking for better ways to assist cancer patients to navigate the increasingly complex cancer maze.

We have invited a group of Medical scientists and clinicians to come together in Brisbane to discuss new ways to tackle the issue of improvements in the medical treatments of cancer. Conventional cancer treatments often get bad press, but the fact is they save lives, true not all lives; but significant enough particularly in some areas of medicine. As one solution to the growing swell of alternative cancer treatments; this group are looking at what can be done to improve conventional cancer medicine by extending the scientific knowledge of our immune system; utilising its inbuilt power and ability to “remember” pathogens, and invaders like cancer cells and proactively destroy them.

GG and Martin AShdown 31 Oct 14 interview  - Copy (2)
Martin Ashdown Melbourne University & Grace Gawler

Immune therapies and the discovery of the immune cycle in cancer patients to help better time delivery of treatments with potentially better outcomes and less side effects; is worthy of attention and research funding in the current climate.

Jeffrey Deslandes – recovered patient using cancer vaccines after 4th recurrence stage 4 lymphoma and now 8.5 years clear will also be in Brisbane this week. His book “From Cancer Good things Grow” tells his story of recovery using cancer vaccines made from his own tissue. All proceeds from the book go to research & Development and clinical application of cancer vaccines in Australia.

I will also be interviewing Prof Brendon Coventry on this weeks Navigating the Cancer Maze internet radio show.
Stay tuned for more updates…..

Until next time…

Grace

Can Fibre Diffraction Diagnosis Detect Cancer Years Before its Onset | Yes says Professor Veronica James

Navigating the Early Detection Maze! Just imagine if cancer could be detected long before the process of a mammogram or PSA test or scan discovered advanced disease? According to Physicist, Professor Veronica James who has devoted her life to Scientific Research in the area of early diagnosis; the answer is a resounding YES!

Navigating the Early Detection Maze! Just imagine if cancer could be detected long before the process of a mammogram or PSA test or scan discovered advanced disease?

Fibre Diffraction Diagnosis
Professor Veronica James

According to Physicist, Professor Veronica James who has devoted her life to Scientific Research in the area of early diagnosis; the answer is a resounding YES! Just imagine if she is right and there is a strong probability she is; earlier cancer diagnosis than we currently have access to, is possible! Interview Voice America:

Prof James has worked on breast cancer since the 1980s & developed Fibre Diffraction Diagnosis”, a method to detect cancer using x-rays of nail clippings, hair or skin. An unusual concept; but this almost 80 year old Australian scientist has the science and credibility to back up her research results.

One of the fears and anxieties amongst cancer patients I see, is their concern that they may have somehow passed on their cancer genes to the children or grandchildren. Wouldn’t it be wonderful for them to know there was a test that could lead to a clean bill of health or an early diagnosis?

Prof Veronica James is not a name that one recognizes unless you are in the academic research field; and so the question that begs to be asked is – Why Not? What happened to her research and findings and why hasn’t she had the funding to continue her work? These questions that require an answer.

I visited Veronica at her home this week to record an interview for my Voice America Internet Radio Show that aired today on Navigating the Cancer Maze. I was horrified to hear about her battles to get this invaluable contribution to cancer research recognised. Despite her credentials, she has had to fight tremendous battles to assert her research findings in Science. A snippet of the issues she has had to endure are to be found in the Herald-Sun article January 06, 2010!  Titled Professor Veronica James’s quest to shield others by Olga Galacho.  Well worth a read! Here is someone who I consider is a Grand Dame of Science in Australia, a National Treasure. Please contact me via the contact page on the menu if you would like to support Prof James research.

Her research and results from studying early diagnosis of breast cancer using Fibre Diffraction Diagnosis, is astounding.

This story of discovery is amazing and somewhat serendipitous. In 1996, Veronica reported to the medical personnel at Christie’s Hospital Manchester, the 4 changes she had observed in the collagenous ductal tissue of the breast that precede breast cancer noting that, in the final stage, the breast tissue had reversed to foetal tissue.

Rings identified by Prof Veronica James as disease states
Rings identified by Prof Veronica James as disease states

Veronica was asked whether she had observed similar foetal tissue in the skin as had been reported in breast cancer. A subsequent study at the local Daresbury synchrotron of 14 skin samples did show a possible foetal-like change similar to the penultimate change in the breast. Christie’ Hospital Oncologists agreed to provide 200 samples to confirm these results but when she arrived in England to collect them, the samples had disappeared from their freezer. As Veronica had already studied changes in hair in insulin dependent diabetes and was due in Japan the following day, she asked if a clinic was in progress and being told that it was asked if a hair sample could be taken from each of the participants. With hoots of laughter they agreed asking her what she thought she would find. Veronica told them nothing but that she would not be in disgrace in Japan for arriving without any samples. They were still laughing when she collected these samples the next day. When Veronica started to look at the samples the following day in Japan, she found strange rings superimposed on the normal hair patterns and after blaming and reassembling the machine she finally found out that only 8 of the 19 samples showed this ring.

Veronica sent back to England the numbers of these samples thinking that they might have something in common – same family, same shampoo, same hairdressers etc. Their return email stated simply that Veronica had picked out all the breast cancer patients. This was confirmed by taking these and further blinded sets to other synchrotrons. The changes relating to other cancers and Alzheimer’s Disease, were found in the 4000 subsequent blinded tests from 14 different international sources when patients with other cancers were included to prove that the discovered change was specific to breast cancer. As each new change was identified, further studies were undertaken to verify the specificity of each new change.

Professor Veronica James maintains that her results can be easily duplicated if the correct procedures are followed. Basically what Veronica is doing is taking a sample of skin, nail or hair and shining an x-ray beam through it. Upon examination of the x-ray one can observe rings which in their various positions indicate if the patient is developing a particular type of cancer. An absence of rings indicates the patient is healthy. Veronica claims that cancer can be detected very early using her method.

To see a short video with explanations of the test; Fiber Diffraction Diagnosis (FDD) with Prof Veronica James-Please visit the link below. ABC TV – Australia -“The Inventors”.

http://www.abc.net.au/tv/newinventors/txt/s2919200.htm

Research Gate – a portal for academic research lists 52 Publications for Professor James. Her areas of expertise include: Biological Physics, Medical Biochemistry: Proteins And Peptides (Incl. Medical Proteomics), Structural Chemistry And Spectroscopy, Physical Chemistry Of Materials, Medicinal & Bio-molecular Chemistry, Oncology & Carcinogenesis.

AWARDS: Prof James has an Order of Australia Medal for her services to the deaf. 1992 Quota South Pacific Breast Cancer Research Award, 1999 American Biographical Institute Woman of the Year and 2004 International Scientist of the Year IBC Cambridge. She has recently been awarded an honorary doctorate of Science from Cambridge.

There is an annual two day camp called the Veronica James Science Challenge for Hearing Impaired Children supported by the University of Sydney’s Faculty of Medicine through its department of pathology.

DOWNLOAD PUBLICATIONS:

1. extremely early diagnosis of prostate cancer veronica james – Prof Veronica James

2. The Connection Between Presence of Melanoma and changes in Fibre Diffraction Patterns Prof V James

Prof James has had a distinguished university teaching career progressing to Associate Professor, UNSW. She has been Visiting Fellow, Research School of Chemistry ANU, Visiting Fellow, Dep’t of Pathology UWA. Semi retired, she is presently Adjunct Professor, Research School of Chemistry ANU and wishes to continue cancer research to further develop her methods to help humanity. Thank you to Prof James for her permission to use her research and  images on this blog.

Until Next Time……..

Grace

Cancer Vaccines | A survivors story|From Cancer Good Things Grow Grace Gawler

I encored a recent interview with Jeffery Deslandes on my Voice America Internet radio show today for the Christmas period for a special reason. Because his story is both true and inspirational.

I encored a recent interview with Jeffery Deslandes on my Voice America Internet radio show today for the Christmas period for a special reason. Because his story is both true and inspirational. As Jeffrey quotes in his recently released ;  book; “From Cancer Good Things Grow”;  there are about 4,000 new cases of NHL each year in Australia. 1600 Australian die from NHL each year. If this were our road toll and there was an effective way of preventing deaths of even half of that number – there would be campaigns and lots of public and political interest. Why is there such little  interest in cancer immunotherapies? Jeffrey Deslandes is just one of many who have had success with vaccine treatments.

The questions begs – Have we become so conditioned to believing that cancer is a one-way ticket and there’s nothing we can do apart from try alternative medicine and throw out the “conventional medicine” baby with the bathwater?  Have we been convinced that conventional cancer medicine doesn’t work and that all big Jeffrey Deslandes Book 001pharma wants you to do is stay sick to garnish the pockets of doctors?  Have we bought into the rumour that the war on cancer is lost?  These are common statements from the Google cancer entrepreneurs whose aim is to convince patients to follow them, buy their “one size fits all” cancer products and……… take no responsibility for patient outcomes.

I know of far too many  patients who are not here to be with their families this Christmas because they used “faceless” advice from books, CDs or the internet – leaving aside treatable and potentially curable treatments for their cancer until it became obvious that their attempts to replicate the “cures” they have read about; ultimately failed them. This year I have experienced a new phenomenon, receiving many emails from parents who have taken the natural cancer “healing” path with their children using bizarre nutritional regimens, GcMAF, Budwig and Gerson Diets to name a few – most read about these treatments on blogs. Some of these children have been 3 and 5 years of age.  I try my best to influence them towards excellent sources of conventional medicine – but after a few emails – I never hear from them again. This is truly exasperating!!

Genuine, well documented  stories of cancer treatment successes are much needed. Such is the story of how Melbournian Jeffery Deslandes recovered from Stage 4 recurrent lymphoma that had grown resistant to conventional treatment found his remission – now eight and a half years clear. Jeffery did not seek Alternative medicine treatments when his lymphoma recurred again and again; rather he looked outside the conventional box to see what else science-based medicine could offer.

By purchasing Jeffrey Deslandes book (soft Cover /eBook) – you can help to promote the immune therapy he had right here in Australia. All proceeds go toward making this treatment more available for those in our region. PLEASE spread the good news. Vaccine therapies as immunotherapies go wider than just lymphoma. Successes are appearing from many cancer types including melanoma, prostate cancer and many more. If these therapies can be investigated alongside immune cycle research; we may indeed have a two incredibly power non invasive cancer treatment allies. Scroll to end of blog to see the effect of melanoma vaccine.**

Excerpts from Jeffrey Deslandes book “From Cancer Good things Grow”.

 

Chapter 7 -The cancer Returns Again and Again

Non-Hodgkin’s lymphoma is a bit like buffalo grass; it is hard to get out all of the roots and it tends to grow back. I had been informed that my cancer was incurable. It was a real shock at the time.
Non-Hodgkin’s lymphoma (NHL) is Australia’s fifth most common cancer, yet has a very low profile, compared to more publicised cancers such as breast, ovarian, bowel, melanoma and leukaemia. There are about 4,000 new cases of NHL each year in Australia, with about 1,600 deaths each year. That’s about the same as the National Road Toll in this country. Each year we spend billions trying to stop idiots killing each other on the road, yet comparatively little on a disease which is poorly understood. While Australia’s economy is soon to be taxed with the introduction of a Carbon Tax to combat Climate Change. Funny that, I have never known anyone who has died from Climate Change, but I have known scores and scores of people who have succumbed to cancer. We need Governments to spend serious money on cancer research.

After my cancer had returned for the fourth time in 2006, the next mainstream cancer treatment outlined by my specialist, was an autologous stem cell transplant. An autologous stem cell transplant, refers to your own body’s stem cells being first harvested, you are then given high-dose chemotherapy to hopefully kill all cancer in your body, and your stem cells

Jeffrey Deslandes
Jeffrey Deslandes

are then re-infused to build up your white cells, which have been decimated by the chemotherapy. The other option was an allogeneic stem cell transplant; the same procedure but the stem cells are used from a matched donor who is obviously free from cancer. However, for this we would need to find a matched donor, since my brother Ron was not a match, and other brother David was no longer with us. I decided not to take the recommendation of my highly trained lymphoma specialist. I decided that I would need to take charge of my treatment, and find something with a different mode of attack. If something is not working, you don’t keep hitting it with the same old stick! Read on,,,,,,,,

Chapter 8 – Vaccine Therapy–The New Beginning

Through my association with Lymphoma Australia, a fine not-for-profit organisation dedicated to raising awareness and supporting lymphoma patients, I became aware of work being done on vaccines for cancer treatment. This work was still experimental or being proven in clinical trials, but it was not quackery, it was being carried out by highly qualified haematologists and scientists.

My diseased lymph node, and my immature dendritic cells, were processed in the laboratory to manufacture a dendritic cell idiotype vaccine to fight the cancer. It is termed idiotype, because the vaccine is grown from my own cancer cells, and is thus specifically tailored to the idiosyncrasies of my cancer. It is worth noting that there are over 30 sub-types of lymphoma alone, and it is my understanding that each and every lymphoma is going to be somewhat different in its individual characteristics. By using my own lymphoma, we got a perfect match, the exact antibody to my cancer. The laboratory grew the vaccine formulation to make 33 doses of vaccine, which were stored at minus 196 °C in liquid nitrogen, and could be kept for perpetuity. Each dose of vaccine is about 1 ml, about a fifth of a teaspoon, but it contains about five million cells. Yes, that’s five million cells, each with a message for my immune system. The message was “this is what the cancer looks like, now do your job like you are supposed to, and go seek and destroy”.  Excerpt: “From Cancer Good Things Grow”

Help save a life ……… Readers of this blog – please help us to help others through cancer education. By passing on this blog or an episode from Voice America – you could also help cancer patients to re-frame their cancer experience and learn about the nature of cancer and how to outsmart it with science-based medicine.

May your Christmas season be filled with joy, love, passion and compassion….

Until next time….

Grace

**Warning:  Below – graphic image melanoma – positive results from repeated vaccine cancer treatments.

Conclusions: Prolonged, repetitive VMCL vaccination immunotherapy appears to be a clinically effective means
of generating relatively high CR rates, useful clinical responses and long-term survivals, with little toxicity, but
remains notably under-explored. Successive immunomodulation might explain the results. Closer analysis of
repetitive dosing is required.

Melanoma vaccines
Successful application of repeated dosing with Melanoma vaccines. Research- Brendon Coventry

Cancer Doesn’t Stop for Christmas | Dealing with the Challenges-Grace Gawler Voice America

Navigating the Cancer Maze represents the culmination of my 40 years experience working at the coalface of cancer in what I call cancer supportive care medicine. As a young girl of about 8 years of age – I had two ambitions in life; to research cancer or become a veterinary surgeon. The universe works in mysterious ways. In 1976 I married a veterinarian who had cancer.

LISTEN TO GRACE GAWLER  VOICE AMERICA AUDIO
Click headphones to listen to today’s show at Voice America

Today’s Navigating the Cancer Maze, covers several areas important to Cancer patients.

In addition to this blog – gracegawlermedia – on Sunday 21st December 2014 – I will be launching a new blockbuster or should I say myth-buster blog – Grace Gawler Blog: The Thinking Person’s Guide to the Truth behind Common Cancer Mythology.

Navigating the Cancer Maze represents the culmination of my 40 years experience working at the coalface of cancer in what I call cancer supportive care medicine. As a young girl of about 8 years of age – I had two ambitions in life; to research cancer or become a veterinary surgeon. The universe works in mysterious ways. In 1976 I married a veterinarian who had cancer.

It happened just a few days before Christmas in 1974 – 40 years ago when I had just turned 21. Suddenly I became a carer of a cancer patient who was my boyfriend and employer.

My wedding day 28 Feb 1976 - 21 years and full-time carer
My wedding day 28 Feb 1976 – 21 years and full-time carer

 Like many today I had no experience in how to cope personally or how to help the patient who was my charge. I had to improvise and learn along the way. Added to this, my boyfriend, who later became my husband when he was given a prognosis 6 weeks to live; was an amputee. He had lost his leg to bone cancer just after Christmas, January 1975. He survived, we had 4 children and now 4 grandchildren. I learned a lot during that “hands-on period” that added to later qualifications. My story of those times is recorded in my Memoirs: Grace Grit and Gratitude. (2008 – eBook available)

See You tube: Grace Grit and Gratitude  Also visit on the menu of this blog –  “Ian Gawler Cancer?”

Moving forward to 2012 I realised that consulting with patients and public speaking was not enough. With cancer incidence rising, what I had learned needed a Global voice; an opportunity to take what I had learned so far and add medical expertise in current cancer treatments and research combined with patients’ experiences.

Available eBook - buy soft cover Australia only
Available eBook – buy soft cover Australia only

Patient’s need reliable and genuine information when they are in the fight for their lives! 2014 marks 2 years on air with Voice America’s Health and Wellness Channel hosting ‘Navigating the Cancer Maze’. We want as many people as possible to know about Navigating the Cancer Maze internet radio because my Charity The Grace Gawler Institute sponsors this show to provide education and information free to all in need. Please visit the Website for our Christmas Fundraiser to support the show for 2015: “Move the World with Grace”

On this week’s pre-Christmas show I discuss key issues for cancer patients that have been highlighted by our guests on Navigating the Cancer Maze throughout 2014; a year of challenges and excitements in the Global Cancer Community. We will take a look at the impact of some of cancer’s entrepreneurs Including Wellness Warrior-Jess Ainscough, who has influenced many patients to follow the natural path to cancer healing, albeit encouraged by the Ian Gawler recovery story, which as you know, was highly likely to have been a misdiagnosis.

Unfortunately, but as expected; Jess’s Epithelioid sarcoma, a cancer that moves slowly has now progressed to a serious degree. Her mum recently died from breast cancer doing the same regimen. Entrepreneurial patients like Jess Ainscough have a huge influence on cancer patient’s treatment decisions. I truly despair at these stories. I hear from cancer patients like Jess daily and see them in my practice with the most horrendous fungating cancers that one would would expect to see in a third world country. I am passionate to educate cancer patients about the dangers of taking the 100% natural therapies approach. As a trained naturopath and herbalist-I am horrified by what I see hear and read about natural cancer cures!
More on this visit-Science -based Medicine Blog and See  Jessica Ainscough Wellness Warrior

Finally….Cancer Doesn’t Stop at Christmas:While for some this is a happy time of year – for others Christmas and New Year celebrations can be very a difficult & emotional time for those currently dealing with life challenging illness, including patients’ families. Also challenging is the person who may be missing from this year’s Christmas table. Please see helpful resources below – also listen to today’s show for helpful tips
Many of my Guests on Navigating the Cancer Maze have authored some fine books. I have listed them below. These are books of substance that contain valid and useful information for patients and families. Recommended for Christmas gifts or personal reading

Resources/Books mentioned on today’s show from my 2014 Guests:
BOOKS

  1. From Cancer Good Things Grow Jeffrey Deslandes – 8.5 year survivor of stage 4 lymphoma after failed treatments – 4 recurrences. Success with Dendritic cell vaccines. Pub  Balboa Pressall proceeds go to R& D Of DC Vaccines.
  2. “Three Months: A Caregiving Journey from Heartbreak to Healing” by Dietrich Stroeh Buy at Amazon
  3.  Recent Release-” Survivorship: Living Well During and After Cancer” by Dr Barrie Cassileth –
    Buy at:  http://www.cancercarestore.com/survivorship-living-well-during-and-after-cancer
  4. “Bad to the Bone: the True Story of David Tuccaro, Jr” – by David Tuccaro, Jr successful leukemia treatment- Buy at Amazon
  5. “Lead With Your Heart: Creating a Life of Love, Compassion, and Purpose”  by Regina Cates Buy at Amazon
  6. “The Man who Saved a Million Lives” – by Prof Ian Frazer Buy at Amazon
  7. Spontaneous Remission: An Annotated Bibliography by Caryle Hirshberg and Brendon O’Regan – Access this via IONS- Free chapter downloads:
    http://noetic.org/library/publication-books/spontaneous-remission-annotated-bibliography/

Movies:

Debbie Franke Ogg had a Hollywood Movie made about her life and recovery from Stage 4 Lymphoma. It starred Sam Neil and Anne Archer. First titled “A Leap of Faith” – the movie was later titled a “Question of Faith”. Debby is perhaps one of the few of millions who had a spontaneous remission from her cancer without medical treatment. The movie can be found online by typing the title into Google. Now a therapist in NY USA – Watch Movie online   Contact Debby.

Cancer Doesn’t Stop at Christmas: Help for those who may have lost a loved one this year. Resources provided by Beth O’Brien: a guest on this year’s Navigating the Cancer Maze.
http://seasonsofgrief.com.au/about-beth/
www.australiancelebrations.com.au
http://deathcafe.com/
https://www.suicidecallbackservice.org.au
http://www.livingisforeveryone.com.au
http://suicidepreventionaust.org/resources/
BOOK recommended by Beth:
Dying to be Free: A healing guide for families after a suicide (Beverly Cobain, Jean Larch) buy at Amazon
The Grief Recovery Handbook: The action program for moving beyond Death, Divorce and other losses by John W James and Russell Friedman Buy at Amazon

Listen to today’s show at
http://www.voiceamerica.com/episode/82356/cancer-doesnt-stop-for-christmas-dealing-with-the-challenges

Join Voice America for free: http://www.voiceamerica.com/member/register

OR Join this blog for weekly updates delivered to your email box.

Until next time – Compliments of the Christmas Season

Grace

From Cancer Good Things Grow – A Survivor’s Story|Grace Gawler Interviews Jeffrey Deslandes

Jeffrey Deslandes thought he had it all. The father of five children, he had his whole life ahead of him. But on one fateful day in 1999, he believed it was all over when he was diagnosed with an aggressive form of cancer. He was wrong. His life had just begun!

from cancer good things growA true story of survival: Share the good news. Listen to Navigating the Cancer Maze: From Cancer Good Things Grow.  If you know someone with lymphoma, leukaemia, melanoma or other cancers – you need to tell them about Jeffrey Deslandes and how he survived and thrive thanks to cancer vaccines. They need to read his story.

Jeffrey Deslandes thought he had it all. The father of five children, he had his whole life ahead of him. But on one fateful day in 1999, he believed it was all over when he was diagnosed with an aggressive form of cancer. He was wrong. His life had just begun!

His diagnosis, B cell non-Hodgkin’s lymphoma, follicular mixed small and large cell, Stage IV, with bcl-2 gene translocation, with spleen and bone marrow involvement. His prognosis; poor.

His is an inspiring, positive, and true story about surviving cancer—and the things it teaches you. You grow as a person. You learn what is really important in life. You discover who your true friends are. Listen to my interview with Jeffrey on Voice America’s Health & Wellness Channel – Navigating the Cancer Maze: From Cancer Good Things Grow.  (Note: The show is sponsored by the Grace Gawler Institute. Free to listen – live stream on demand – select link above or download and listen another time – share with friends and fellow patients. Live broadcast 12 noon Friday – USA time(PST) – Australia – 6 am Qld time.

After traditional treatments, such as chemotherapy, failed to control his cancer, Jeffrey started looking for emerging therapies. When he learned of an experimental treatment involving a personalised vaccine protocol, he pursued it. It is now feasible to have something good—a personalised cancer vaccine—created from something bad—your cancer. This one-of-a-kind vaccine reeducated his immune system so that it could identify and destroy his cancer.

Jeffrey’s story is not a gloom-and-doom tale of yet another poor soul enduring cancer treatment. Instead, he shares his story in the hope of reaching and inspiring other cancer patients who may have given up. Some of the stories in this book come from his deep spiritual core, but he is not a “religious” man. He doesn’t require you to believe these stories, only to know that everything detailed in this book is true.

See Press pass info – share this link to others.

ABOUT Jeffrey Deslandes: Jeffrey is a native of Melbourne, Australia. He has a Masters in Engineering Science, and is a Doctor of Philosophy, attained at the University of Melbourne. He has been married twice and has five children.  His is an inspiring, positive, and true story about surviving cancer—and the things it teaches you. You grow as a person. You learn what is really important in life. Compelled to write about his experience. “From Cancer Good Things Grow” was published recently. Available as ebook and soft cover.(Balboa Press) BUY online at: Balboa Press:

All proceeds from the sale of this book go directly to cancer vaccine research in Brisbane where Jeffrey had his treatment. He wants more people to know about his doctor and the the hope that vaccines bring for recovery. For more information about Jeffrey’s treatment – please contact me via the contact page on this BLOG or via www.gracegawlerinstitute.com

Note: Dendritic cell vaccines are highly technical and need rigorous quality control and expertise. Ask me for further information on how to access this treatment.

VOICE AMERICA LINK to listen to audio:

http://www.voiceamerica.com/episode/82217/from-cancer-good-things-grow-a-survivors-story

Until next time…… Grace

Options, Choices and Treatments for Cancer Recovery| Navigating the Cancer Maze

New cancer treatments are always controversial; BUT – this method is not a treatment. It’s a smart approach. A Smart approach that utilizes all that we know so far about cancer. It works because ultimately; our innate immune system knows what to do.

Options, Choices and Treatments for Cancer Recovery: De mystifying the oscillating the immune cycle.

When my ex husband and I had the idea for starting support groups for cancer patients in the early 1980’s. cancer organizations, patients and doctors were initially not supportive. In fact they were skeptical. They could not see any possible therapeutic benefit could come from people attending a support group.  How wrong they were! Move forward Body rhythms diagram40 years! Yes this December marks my beginning working with cancer patients 40 years ago in a time when there was no support in the health system and no support groups. Now, the benefit of patients attending structured supports and the well being benefit is indisputable.

There are still many new areas to explore, which leads me to discussing the immune cycle. It would seem that during 2014 on Navigating the Cancer Maze – we uncovered and delivered some significant “missing” pieces of the cancer treatment puzzle. It is my hope that as 2014 comes to an end – that 2015 will truly usher in a new paradigm in cancer treatments. The foundation has been laid, extensive research already done, the concept has been introduced worldwide – the  immune cycle measurement is here – NOW!
Now it is up to cancer patients to prove Martin Ashdown and Brendon Coventry right….or wrong. I liked it when Martin Ashdown said – “We believe this is so, a breakthrough – but we are open to being proven wrong!” As in the early days of my first charitable  foundation – it was people power – patient power that made a difference to the success of the Cancer Support Group Movement. Once told there would likely be a measured benefit from attending a support group – the press broadcast the news and the patients came on board en masse!

New cancer treatments are always controversial; BUT – this method is not a treatment. It’s a smart approach. A Smart approach that utilizes all that we know so far about cancer. It works because ultimately; our innate immune system knows what to do. It is just in temporary overwhelm. So doesn’t it make perfect sense that to find the best time to work in synch within the cycle of each person’s immune system to add the best chemotherapy or monoclonal antibody or other targeted treatment. Isn’t this the personalized approach we have been searching for? We all thought it would come in a pill – not an approach and that’s a paradigm shift that some in the world of science and medicine are struggling with.

measuring immune cycleKnowing how one’s immune cycle oscillates holds a clue, “the missing link” that can direct doctors to seek the best time to treat patients in their personal window of opportunity. Then within the parameters of what we know they will have the best chance of a good response or complete response to treatment. (CR)

When cancer cells challenge us – they are also smart. They are a part of us created by our internal systems. You could define cancer as an internal systems error!  These cancer cells cleverly recruit our intelligent mechanisms using them for their own growth and survival. It seems a bit crazy that something that wants to survive – kills its host. But – that’s life! To listen to the latest Voice America related to this blog visit:
http://www.voiceamerica.com/episode/82056/options-choices-and-treatments-for-cancer-recovery

So – I believe as do Ashdown and Coventry – that if there is enough of the immune response left in a patient – that the cycle can still be measured and timed so administer the right treatment at the right time. It is simple enough – the only real cost being a series of blood tests. Then finding a doctor who will look at the science and research and say yes – they administer treatment during the 12 hour window of opportunity. The Grace Gawler Institute is keen to let you know and experience the immune cycle for yourself. Please Read more below or join the immune cycle registry at:

http://www.gracegawlerinstitute.com/immune-cycle-registry/ also see our Next “Survivor Academy” Course!

Martin Ashdown and Brendon Coventry have built upon earlier excellent work in the study of chronobiology: Below are references given on Navigating the Cancer Maze today: I have provided abstract content as well as links.

Until next time……Grace

  • Annu Rev Pharmacol Toxicol. 2010;50:377-421. doi: 10.1146/annurev.pharmtox.48.113006.094626.
    Circadian timing in cancer treatments.
    Lévi F1, Okyar A, Dulong S, Innominato PF, Clairambault J.
    Author information
    Abstract
    The circadian timing system is composed of molecular clocks, which drive 24-h changes in xenobiotic metabolism and detoxification, cell cycle events, DNA repair, apoptosis, and angiogenesis. The cellular circadian clocks are coordinated by endogenous physiological rhythms, so that they tick in synchrony in the host tissues that can be damaged by anticancer agents. As a result, circadian timing can modify 2- to 10-fold the tolerability of anticancer medications in experimental models and in cancer patients. Improved efficacy is also seen when drugs are given near their respective times of best tolerability, due to (a) inherently poor circadian entrainment of tumors and (b) persistent circadian entrainment of healthy tissues. Conversely, host clocks are disrupted whenever anticancer drugs are administered at their most toxic time. On the other hand, circadian disruption accelerates experimental and clinical cancer processes. Gender, circadian physiology, clock genes, and cell cycle critically affect outcome on cancer chronotherapeutics. Mathematical and systems biology approaches currently develop and integrate theoretical, experimental, and technological tools in order to further optimize and personalize the circadian administration of cancer treatments.
    PMID:
    20055686
    [PubMed – indexed for MEDLINE]
  • http://www.ncbi.nlm.nih.gov/pubmed/20055686

Ann Pharm Fr. 2008 Jun;66(3):175-84. doi: 10.1016/j.pharma.2008.05.003.
[The circadian-timing system: a determinant of drug activity and a target of anticancer treatments].
[Article in French]
Lévi F.
Author information
Abstract
Cellular proliferation and drug detoxification are controlled over the 24h by the circadian-timing system, whose disruption can favor malignant processes. Thus, prolonged shift work appears to increase the risk of breast, colon or prostate cancer. Alterations in circadian physiology and/or molecular-clock genes accelerate cancer progression in experimental models and in cancer patients. In addition, anticancer treatments can also dampen or reinforce the circadian-timing system, as a function of dose and time of administration. The adjustment of anticancer-drug delivery to the circadian-timing system (chronotherapeutics) has allowed to reduce five-fold the incidence of severe adverse events as compared to constant rate infusion or wrongly-timed chronomodulated delivery in cancer patients. In experimental models, the best antitumor efficacy is usually obtained following treatment delivery near the least toxic time, a statement that also seems to apply to patients. Dedicated technologies include programmable in time pumps and rhythm monitors and are required for chronotherapeutics. Recent results have revealed that the optimal chronotherapeutic schedule could differ as a function of gender and circadian physiology. In conclusion, the circadian-timing system was shown to negatively control malignant proliferation via partly identified molecular mechanisms. The components of the circadian-timing system thus constitute new potential therapeutic targets in oncology. Mathematical models help toward a better understanding of the role of variability for the determination of the optimal chronotherapeutic schedule and constitute useful tools for the personalization of cancer chronotherapeutics.

http://www.ncbi.nlm.nih.gov/pubmed/18706346

Handb Exp Pharmacol. 2013;(217):261-88. doi: 10.1007/978-3-642-25950-0_11.
Cancer chronotherapeutics: experimental, theoretical, and clinical aspects.
Ortiz-Tudela E1, Mteyrek A, Ballesta A, Innominato PF, Lévi F.
Author information
Abstract
The circadian timing system controls cell cycle, apoptosis, drug bioactivation, and transport and detoxification mechanisms in healthy tissues. As a consequence, the tolerability of cancer chemotherapy varies up to several folds as a function of circadian timing of drug administration in experimental models. Best antitumor efficacy of single-agent or combination chemotherapy usually corresponds to the delivery of anticancer drugs near their respective times of best tolerability. Mathematical models reveal that such coincidence between chronotolerance and chronoefficacy is best explained by differences in the circadian and cell cycle dynamics of host and cancer cells, especially with regard circadian entrainment and cell cycle variability. In the clinic, a large improvement in tolerability was shown in international randomized trials where cancer patients received the same sinusoidal chronotherapy schedule over 24h as compared to constant-rate infusion or wrongly timed chronotherapy. However, sex, genetic background, and lifestyle were found to influence optimal chronotherapy scheduling. These findings support systems biology approaches to cancer chronotherapeutics. They involve the systematic experimental mapping and modeling of chronopharmacology pathways in synchronized cell cultures and their adjustment to mouse models of both sexes and distinct genetic background, as recently shown for irinotecan. Model-based personalized circadian drug delivery aims at jointly improving tolerability and efficacy of anticancer drugs based on the circadian timing system of individual patients, using dedicated circadian biomarker and drug delivery technologies.
http://www.ncbi.nlm.nih.gov/pubmed/23604483

Chronobiol Int. 2002 Jan;19(1):1-19.
From circadian rhythms to cancer chronotherapeutics.
Lévi F.
Author information
Abstract
Mammalian circadian rhythms result from a complex organization involving molecular clocks within nearly all “normal” cells and a dedicated neuroanatomical system, which coordinates the so-called “peripheral oscillators.” The core of the central clock system is constituted by the suprachiasmatic nuclei that are located on the floor of the hypothalamus. Our understanding of the mechanisms of circadian rhythm generation and coordination processes has grown rapidly over the past few years. In parallel, we have learnt how to use the predictable changes in cellular metabolism or proliferation along the 24h time scale in order to improve treatment outcome for a variety of diseases, including cancer. The chronotherapeutics of malignant diseases has emerged as a result of a consistent development ranging from experimental, clinical, and technological prerequisites to multicenter clinical trials of chronomodulated delivery schedules. Indeed large dosing-time dependencies characterize the tolerability of anticancer agents in mice or rats, a better efficacy usually results from treatment administration near the least toxic circadian time in rodent tumor models. Programmable in time multichannel pumps have allowed to test the chronotherapy concepts in cancer patients and to implement chronomodulated delivery schedules in current practice. Clinical phase I and II trials have established the feasibility, the safety, and the activity of the chronotherapy schedules, so that this treatment method has undergone further evaluation in international multicenter phase III trials. Overall, more than 2,000 patients with metastatic disease have been registered in chronotherapy trials. Improved tolerability and/or better antitumor activity have been demonstrated in randomized multicenter studies involving large patient cohorts. The relation between circadian rhythmicity and quality of life and even survival has also been a puzzling finding over the recent years. An essential step toward further developments of circadian-timed therapy has been the recent constitution of a Chronotherapy cooperative group within the European Organization for Research and Treatment of Cancer. This group now involves over 40 institutions in 12 countries. It is conducting currently six trials and preparing four new studies. The 19 contributions in this special issue reflect the current status and perspectives of the several components of cancer chronotherapeutics.
PMID:
11962669
[PubMed – indexed for MEDLINE]

http://www.ncbi.nlm.nih.gov/pubmed/11962669
Cancer Causes Control. 2006 May;17(4):611-21.
Chronotherapeutics: the relevance of timing in cancer therapy.
Lévi F.
Author information
Abstract
BACKGROUND:
Cell physiology is regulated along the 24-h time scale by a circadian timing system composed of molecular clocks within each cell and a central coordination system in the brain. The mammalian molecular clock is made of interconnected molecular loops involving at least 12 circadian genes. The cellular clocks are coordinated by the suprachiasmatic nuclei, a hypothalamic pacemaker which also helps the organism adjust to environmental cycles. The rest-activity rhythm is a reliable marker of the circadian system function in both rodents and man. This circadian organization is responsible for predictable changes in the tolerability and efficacy of anticancer agents, and possibly also in tumor promotion or growth.
METHODS:
Expected least toxic times of chemotherapy were extrapolated from experimental models to human subjects with reference to the rest-activity cycle. The clinical relevance of the chronotherapy principle, i.e. treatment administration as a function of rhythms, has been demonstrated in randomized multicenter trials.
RESULTS:
Chronotherapeutic schedules have been used to safely document the activity of the association of oxaliplatin, 5-FU and leucovorin against metastatic colorectal cancer and to set up a new medicosurgical management of this disease which achieved unprecedented long term survival.
CONCLUSION:
The chronotherapy concept offers further promises for improving current cancer treatment options as well as for optimizing the development of new anticancer or supportive agents.
PMID:
16596317
[PubMed – indexed for MEDLINE]

Mol Med. 2012 Dec 6;18:1249-60. doi: 10.2119/molmed.2012.00077.
Circadian rhythm disruption in cancer biology.
Savvidis C1, Koutsilieris M.
Author information
Abstract
Circadian rhythms show universally a 24-h oscillation pattern in metabolic, physiological and behavioral functions of almost all species. This pattern is due to a fundamental adaptation to the rotation of Earth around its own axis. Molecular mechanisms of generation of circadian rhythms organize a biochemical network in suprachiasmatic nucleus and peripheral tissues, building cell autonomous clock pacemakers. Rhythmicity is observed in transcriptional expression of a wide range of clock-controlled genes that regulate a variety of normal cell functions, such as cell division and proliferation. Desynchrony of this rhythmicity seems to be implicated in several pathologic conditions, including tumorigenesis and progression of cancer. In 2007, the International Agency for Research on Cancer (IARC) categorized “shiftwork that involves circadian disruption [as] probably carcinogenic to humans” (Group 2A in the IARC classification system of carcinogenic potency of an agent) (Painting, Firefighting, and Shiftwork; IARC; 2007). This review discusses the potential relation between disruptions of normal circadian rhythms with genetic driving machinery of cancer. Elucidation of the role of clockwork disruption, such as exposure to light at night and sleep disruption, in cancer biology could be important in developing new targeted anticancer therapies, optimizing individualized chronotherapy and modifying lighting environment in workplaces or homes.
PMID:
22811066
[PubMed – indexed for MEDLINE]
PMCID:
PMC3521792
Free PMC Article

Chronobiol Int. 2012 Apr;29(3):227-51. doi: 10.3109/07420528.2012.658127.
Clock genes and clock-controlled genes in the regulation of metabolic rhythms.
Mazzoccoli G1, Pazienza V, Vinciguerra M.
Author information
Abstract
Daily rotation of the Earth on its axis and yearly revolution around the Sun impose to living organisms adaptation to nyctohemeral and seasonal periodicity. Terrestrial life forms have developed endogenous molecular circadian clocks to synchronize their behavioral, biological, and metabolic rhythms to environmental cues, with the aim to perform at their best over a 24-h span. The coordinated circadian regulation of sleep/wake, rest/activity, fasting/feeding, and catabolic/anabolic cycles is crucial for optimal health. Circadian rhythms in gene expression synchronize biochemical processes and metabolic fluxes with the external environment, allowing the organism to function effectively in response to predictable physiological challenges. In mammals, this daily timekeeping is driven by the biological clocks of the circadian timing system, composed of master molecular oscillators within the suprachiasmatic nuclei of the hypothalamus, pacing self-sustained and cell-autonomous molecular oscillators in peripheral tissues through neural and humoral signals. Nutritional status is sensed by nuclear receptors and coreceptors, transcriptional regulatory proteins, and protein kinases, which synchronize metabolic gene expression and epigenetic modification, as well as energy production and expenditure, with behavioral and light-dark alternance. Physiological rhythmicity characterizes these biological processes and body functions, and multiple rhythms coexist presenting different phases, which may determine different ways of coordination among the circadian patterns, at both the cellular and whole-body levels. A complete loss of rhythmicity or a change of phase may alter the physiological array of rhythms, with the onset of chronodisruption or internal desynchronization, leading to metabolic derangement and disease, i.e., chronopathology.
PMID:
22390237
[PubMed – indexed for MEDLINE]